A5026132977- Global Maternal and Child Health
- Vaccine Coverage and Hesitancy
- Child Nutrition and Water Access
- Pneumonia and Respiratory Infections
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Breastfeeding Practices and Influences
- Bacterial Infections and Vaccines
- Malaria Research and Control
- Streptococcal Infections and Treatments
- Poisoning and overdose treatments
- Infant Nutrition and Health
- Respiratory viral infections research
- Neonatal and Maternal Infections
- Epilepsy research and treatment
- Emergency and Acute Care Studies
- Child and Adolescent Health
- Sepsis Diagnosis and Treatment
- Antimicrobial Resistance in Staphylococcus
- Immune responses and vaccinations
- Pregnancy and preeclampsia studies
- Autopsy Techniques and Outcomes
- Hepatitis Viruses Studies and Epidemiology
- Child Nutrition and Feeding Issues
- Global Health Care Issues
Ekiti State University
2016-2025
Afe Babalola University
2023
Federal University Oye Ekiti
2021
University Teaching Hospital
2017-2019
MRC Unit the Gambia
2012-2019
Obafemi Awolowo University
2009-2019
Medical Research Council
2014
Federal Medical Centre
2013
Vaccination has been shown to reduce mortality and morbidity due vaccine-preventable diseases. However, these diseases are still responsible for majority of childhood deaths worldwide especially in the developing countries. This may be low vaccine coverage or delay receipt age-appropriate vaccines. We studied timeliness routine vaccinations among children aged 12–59 months attending infant welfare clinics semi-urban areas The Gambia, a country with high coverage. A cross-sectional survey was...
Conserved pneumococcal proteins are potential candidates for inclusion in vaccines against diseases. In the first part of a two-part study, an investigational vaccine (PHiD-CV/dPly/PhtD-30) containing 10 serotype-specific polysaccharide conjugates (10VT) combined with pneumolysin toxoid and histidine triad protein D (30 μg each) was well tolerated by Gambian children. Part two, presented here, assessed efficacy two PHiD-CV/dPly/PhtD formulations nasopharyngeal carriage (NPC) prevalence...
We evaluated the candidate tuberculosis vaccine M72/AS01 in Bacille-Calmette-Guérin (BCG)-vaccinated infants after or concomitantly with Expanded-Programme-on-Immunization (EPI) vaccines.In a Phase-II study The Gambia (NCT01098474), 2 cohorts of 150 BCG-vaccinated each were randomized 1:1:1. 'Outside-EPI' cohort received one two doses, meningitis vaccine, 1-2 months primary EPI vaccination. 'Within-EPI' doses third last their EPI-regimen, respectively, vaccines alone. Safety, M72-specific...
Neonatal Sepsis remains a major cause of morbidity and mortality in neonates despite great advances antimicrobial therapy life support measures.To compare the aetiology, risk factors, presentation outcomes care between early onset neonatal sepsis (EOS) late (LOS).Bacterial isolates were identified using blood cultures antibiotic susceptibility testing was done disc diffusion method. The clinical presentation, laboratory findings babies with EOS compared LOS. Statistical significance set at P...
Introduction: dog bites in humans are a major public health problem. Globally, millions of people bitten by dogs but most the fatal cases occur children. There is paucity data on bite related diseases among Nigerian Objectives: to determine pattern injuries and associated problems children seen at Ekiti State University Teaching Hospital.
Despite the global increase in awareness of prostatic diseases resulting from widespread availability screening tools, there is no evidence that knowledge, attitudes and practices Nigerian men have improved regarding diseases.A descriptive cross-sectional study amongst 305 community-dwelling men. Respondents were selected using multi-staged sampling techniques. Knowledge, determined based on responses to a semi-structured KAP questionnaire. Data analyzed SPSS version 18. Pearson's chi-square...
To determine the prevalence of benign prostatic hyperplasia (BPH) and correlates International Prostate Symptom Score (IPSS), peak/maximum flow rate (Qmax), quality life (QoL) score prostate volume (PV) amongst male adults in a rural setting Nigeria. This is community-based cross-sectional survey conducted 615 men. Subjects selected using multi-staged sampling technique were interviewed for presence lower urinary tract symptoms (LUTS) their houses. Severity was assessed (IPSS) questionnaire....
The aim of this study was to determine the prevalence lower urinary tract symptoms (LUTS) and factors influencing healthcare-seeking behavior men with LUTS.A cross-sectional survey performed 658 selected using multi-staged sampling techniques. They were interviewed about LUTS their behavior. data analysed PASW Statistics ver. 18. Associations between specific examined chi-square Fisher exact tests.The overall 59.1%. Storage (48.2%) more prevalent than voiding (36.8%) or post-micturition...
To describe the incidence, and sociodemographic clinical factors associated with preterm birth perinatal mortality in Nigeria.
Background: Neonatal sepsis is a major cause of morbidity and mortality in low- middle-income countries where healthcare resources are often limited. Objectives: This study utilizes machine learning (ML) algorithms to identify determinants neonatal outcomes enhance prediction accuracy. Methods: Data on cases were gathered from the Intensive Care Unit (NICU) at Ekiti State University Teaching Hospital. The target variable was outcome, with predictor variables including weight admission, sex,...
<title>Abstract</title> The full text of this preprint has been withdrawn, as it was submitted in error. Therefore, the authors do not wish work to be cited a reference. Questions should directed corresponding author.
Acute kidney injury (AKI) in children is a disease entity resulting from acute insult to both kidneys leading reduced glomerular filtration rate, impairment of fluid and electrolyte homeostasis the body, accumulation waste product metabolism. It recognized cause morbidity mortality children. Aim: This study aims detect risk factors prevailing causes AKI presenting at tertiary hospital South West Nigeria, identify various intervention/treatment modalities determine predictors outcome....
Two conserved pneumococcal proteins, pneumolysin toxoid (dPly) and histidine triad protein D (PhtD), combined with 10 polysaccharide conjugates from the non-typeable Haemophilus influenzae D-conjugate vaccine (PHiD-CV) in two investigational (PHiD-CV/dPly/PhtD) formulations were immunogenic well-tolerated when administered to Gambian children. Here, we report immunogenicity of conjugates, reactogenicity co-administered routine vaccines. In this phase II, controlled, observer-blind,...
Background: Little information is available about the aetiology and epidemiology of serious bacterial infections in Nigeria. This study determined isolates from blood cerebrospinal fluid (CSF) children presenting emergency room a teaching hospital Method: From October 2005 to December 2006, aged two 60 months with signs acute systemic were recruited. Blood culture CSF specimens collected processed using standard microbiological protocols. Data analysed SPSS version 11 software. Results: Two...
BACKGROUND: Prompt and accurate diagnosis is needed to prevent the untoward effects of anaemia on children. Although haematology analyzers are gold standard for measurement haemoglobin or haematocrit diagnosis, they often out reach most health facilities in resource-poor settings thus creating a care gap. We conducted this study examine agreement between point-of-care device analyzer determining levels children determine its usefulness diagnosing settings.METHODS: EDTA blood samples...
Early sickle cell disease (SCD) diagnosis has shown promise in combating SCD many countries. The aim of this study was to assess the practice and perception early among a group parents physicians Nigeria. Patients Methods. This cross-sectional descriptive conducted opinions 135 caring for patients 164 mothers children with southwestern state Nigeria.Most 132 (97.8%) were aware prenatal diagnosis, but only 51 (37.8%) would recommend it. Most 129 (95.6%) routinely premarital genetic counseling...
Child sexual assault (CSA) is a global health problem which affects many children and often under-reported in developing countries. Data on CSA are few these countries.This study aimed to review the pattern medical care of victims tertiary hospital over 39-month period.This retrospective, descriptive study. Case files 28 cases were retrieved from those 6535 patients seen paediatric out-patient department Ekiti State University Teaching Hospital between 1 January 2010 31 March 2013.Victims...
Introduction: Poisoning is a preventable cause of childhood morbidity and mortality. Information on poisoning in the developing world scanty. This study describes profile third hospital.Materials Methods: Children admitted with over 48-months period at Ekiti State University Teaching Hospital Ado-Ekiti, Southwest Nigeria, were reviewed.Results: It was found that 81 5256 admissions representing 1.54% total due to poisoning. Kerosene, Drugs, Alcohol based herbal concoction, pesticides,...
Background: Human milk bank is a sustainable source of donor human (DHM) which an acceptable alternative to the mother’s and it not routinely available in Nigeria, multi-ethnically diverse country. The study aimed assess willingness donate or accept among pregnant women mothers attending antenatal, immunization, outpatient, under-five, neonatal follow-up clinics selected health facilities Ekiti State, Southwest Nigeria. Study Design Methods: A descriptive cross-sectional, mixed methods...
Mother-to-child transmission remains an important mode of hepatitis B infection particularly in endemic areas. The knowledge and practices pregnant women about mother-to-child (MTCT) virus (HBV) may influence the uptake strategies to reduce infection.This study assessed willingness preventive services among Ado-Ekiti, Nigeria.This was a cross-sectional that involved 373 at Ekiti State University Teaching Hospital (EKSUTH) Maternal Child Specialist Clinics, Nigeria. A structured questionnaire...
To determine the prevalence of primary postpartum haemorrhage (PPH), risk factors, and maternal neonatal outcomes in a multicentre study across Nigeria.