A5073829389- Lichen and fungal ecology
- Botany and Plant Ecology Studies
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Mycorrhizal Fungi and Plant Interactions
- Bryophyte Studies and Records
- Forest Ecology and Biodiversity Studies
- Species Distribution and Climate Change
- Biocrusts and Microbial Ecology
- Ecology and Vegetation Dynamics Studies
- Heavy metals in environment
- Cancer Treatment and Pharmacology
- Lung Cancer Treatments and Mutations
- Metastasis and carcinoma case studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Mediterranean and Iberian flora and fauna
- Genetic factors in colorectal cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Geology and Paleoclimatology Research
- Building materials and conservation
- Plant and animal studies
- Allergic Rhinitis and Sensitization
- Plant Ecology and Soil Science
- Lung Cancer Research Studies
- Colorectal Cancer Surgical Treatments
University of Genoa
2016-2025
Universität Hamburg
2022
University of Florence
2022
University of Bologna
2022
University of Minnesota, Duluth
2022
Ospedali Riuniti Marche Nord
2011-2021
Azienda Ospedaliera Sant'Andrea
2021
San Salvatore Hospital
2004-2019
University of Siena
2017
Fondazione Poliambulanza Istituto Ospedaliero
2016
PURPOSE: We performed a randomized, double-blind, placebo-controlled trial to assess the efficacy of glutathione (GSH) in prevention oxaliplatin-induced neurotoxicity. PATIENTS AND METHODS: Fifty-two patients treated with bimonthly oxaliplatin-based regimen were randomized receive GSH (1,500 mg/m 2 over 15-minute infusion period before oxaliplatin) or normal saline solution. Clinical neurologic evaluation and electrophysiologic investigations at baseline after four (oxaliplatin dose, 400 ),...
Biodiversity continues to decline in the face of increasing anthropogenic pressures such as habitat destruction, exploitation, pollution and introduction alien species. Existing global databases species' threat status or population time series are dominated by charismatic The collation datasets with broad taxonomic biogeographic extents, that support computation a range biodiversity indicators, is necessary enable better understanding historical declines project - avert future declines. We...
The objective is to investigate whether polymorphisms with putative influence on fluorouracil/oxaliplatin activity are associated clinical outcomes of patients advanced colorectal cancer treated first-line oxaliplatin, folinic acid, and fluorouracil palliative chemotherapy.Consecutive were prospectively enrolled onto medical oncology units in Central Italy. Patients required have cytologically/histologically confirmed metastatic disease at least one measurable lesion. Peripheral blood...
The objective of this study was to investigate the efficacy first-line chemotherapy containing irinotecan and/or oxaliplatin in patients with advanced mucinous colorectal cancer. Prognostic factors associated response rate and survival were identified using univariate multivariate logistic Cox proportional hazards analyses. population included 255 patients, whom 49 (19%) had 206 (81%) non-mucinous overall rates for tumours 18.4 (95% CI, 7.5–29.2%) 49% 42.2–55.8%), respectively (P=0.0002)....
The European biodiversity and forest strategies rely on sustainable management (SFM) to conserve biodiversity. However, current sustainability assessments hardly account for direct indicators. We focused multi-taxon to: i) gather map the existing information; ii) identify knowledge research gaps; iii) discuss its potential. established a network fit data species, standing trees, lying deadwood sampling unit description from 34 local datasets across 3591 units. A total of 8724 species were...
To investigate whether polymorphisms with putative influence on fluorouracil/cisplatin activity are associated clinical outcomes of patients advanced gastric cancer (AGC).Peripheral blood samples from 175 prospectively enrolled AGC treated palliative chemotherapy were used for genotyping 13 in nine genes (TS, MTHFR, XPD, ERCC1, XRCC1, XRCC3, GSTPI, GSTTI, GSTMI). Genotypes correlated to response and survival.The overall rate was 41%, the median progression-free survival (PFS) 24 weeks...
No established second-line chemotherapy is available for patients with advanced gastric cancer failing to respond or progressing first-line chemotherapy. However, 20-40% of these commonly receive We evaluated the influence clinico-pathologic factors on survival 175 patients, who received at three oncology departments. Univariate and multivariate analyses found five which were independently associated poor overall survival: performance status 2 (hazard ratio (HR), 1.79; 95% CI, 1.16-2.77;...
This work provides the ethnobotanical data concerning traditional use of medicinal plants in Macedonia region (Northern Greece), which has, up to now, been poorly investigated. The aim present study was collect, analyze, and evaluate information on among different population groups living Central Macedonia. carried out area two small cities, Edessa Naoussa, nearby villages. were gathered through extensive semistructured interviews. informants belonged areas involved, at least partially,...
Ifosfamide and cisplatin cause urinary loss of carnitine, which is a fundamental molecule for energy production in mammalian cells. We investigated whether restoration the carnitine pool might improve chemotherapy-induced fatigue non-anaemic cancer patients. Consecutive patients with low plasma levels who experienced during chemotherapy were considered eligible study entry. Patients excluded if they had anaemia or other conditions thought to be causing asthenia. Fatigue was assessed by...
Patients with advanced gastric cancer unresponsive or progressing after PELF chemotherapy (5-fluorouracil, leucovorin, cisplatin and epidoxorubicin) received paclitaxel at the dose of 225 mg/m2 every 3 weeks, over h infusion. Thirty-six patients entered study, all them were evaluable for response toxicity. Toxicity was mild: apart from alopecia, grade toxicities leukopenia thrombocytopenia in six patients, 2 neurotoxicity seven patients. Eight (22.2%, 95% CI: 9-35%) achieved an objective...
The interpretation of lichen bioaccumulation data is paramount importance in environmental forensics and decision-making processes. By implementing basic ideas underlying previous interpretative scales, new dimensionless, species-independent “bioaccumulation scales” for native transplanted lichens are proposed. Methodologically consistent element concentration datasets were populated with from biomonitoring studies relying on lichens. scale was built up by analyzing the distribution ratios...