A5101874880- Obstructive Sleep Apnea Research
- Neurobiology and Insect Physiology Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Retinal Development and Disorders
- Airway Management and Intubation Techniques
- Heat shock proteins research
- Neuroinflammation and Neurodegeneration Mechanisms
- Nanoplatforms for cancer theranostics
- Cellular transport and secretion
- Total Knee Arthroplasty Outcomes
- Cardiovascular Effects of Exercise
- Heart Rate Variability and Autonomic Control
- Pediatric health and respiratory diseases
- Cardiovascular Health and Disease Prevention
- TGF-β signaling in diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Bone Metabolism and Diseases
- Neurogenesis and neuroplasticity mechanisms
- Anesthesia and Neurotoxicity Research
- Cardiovascular and exercise physiology
- Tracheal and airway disorders
- Cancer, Hypoxia, and Metabolism
- Genetics, Aging, and Longevity in Model Organisms
- Bone health and osteoporosis research
- Circadian rhythm and melatonin
Shandong University of Traditional Chinese Medicine
2008-2021
Shanghai University of Sport
2021
Shanghai Normal University
2020
Louisiana State University Health Sciences Center New Orleans
2014
Chinese Academy of Medical Sciences & Peking Union Medical College
2011
Abstract Exercise training is believed to have a positive effect on cardiac hypertrophy after hypertension. However, its mechanism still not fully understood. Herein, our findings suggest that heat shock transcription factor 1 (HSF1) improves exercise‐initiated myocardial angiogenesis pressure overload. A sustained narrowing of the diagonal aorta (TAC) and moderately‐ intense exercise protocol were imposed HSF1 heterozygote (KO) their littermate wild‐type (WT) male mice. After two months,...
During synaptic development, presynaptic differentiation occurs as an intrinsic property of axons to form specialized areas plasma membrane [active zones (AZs)] that regulate exocytosis and endocytosis vesicles. Genetic biochemical studies in vertebrate invertebrate model systems have identified a number proteins involved AZ assembly. However, elucidating the molecular events assembly spatiotemporal manner remains challenge. Syd-1 (synapse defective-1) Liprin-α been two master organizers...
Photodynamic therapy (PDT) is a promising treatment on neoplastic pathologic tissues, which involves the administration of photosensitizing agent followed by exposure tissue to visible non-thermal light. In our previous findings MPPa was showed be good photosensitizer candidature, because it can lead PC-3M cell line death mainly via apoptotic way. this study, we studied effect overexpression hypoxia inducible factor-1α (HIF-1α) MPPa-PDT. Over expression HIF-1α induced cobalt chloride (CoCl2)...
To investigate the effect of aquaporin-1 (AQP1) on heart edema induced by transverse aortic constriction (TAC) in mice, and to explore whether inhibiting expression AQP1 could attenuate myocardial improve cardiac function.The C57BL/6 mice were divided into four groups: (1) sham group; 2) + acetazolamide group: orally gavaged with (20 mg/kg/day) after operation; (3) TAC a mouse model pressure overload for two weeks; (4) TAC. Cardiac function was detected echocardiography 2 weeks' The ratio...
Background. Aerobic exercise has been proven to have a positive effect on cardiac function after hypertension; however, the mechanism is not entirely clarified. Skeletal muscle mass and microcirculation are closely associated with blood pressure function. Objective. This study was designed investigate effects of aerobic skeletal capillary mass, explore possible mechanisms involved in exercise-induced mitigation dysfunction overload mice. Methods. In this study, 60 BALB/C mice aged 8 weeks...
Aim: To determine whether early exercise in the form of instinctive upward walking can mitigate negative effects cardiac aging Drosophila with cardiac-specific Nmnat Knockdown and overexpression. Methods: Flies were given periods 2 h per day, 5 days a week for 3 weeks starting when they old. The heart model was used conjunction M-mode echocardiography traces to analyze function. Exercise capacity assessed using climbing index, survival rate calculated respect age each subject upon death....
Abstract Background : Jingui Shenqi （JGSQ for short）pills is a traditional Chinese medicine formula, which has the functions of warming and tonifying kidney-yang, generating essence filling marrow, tendons veins bones, improving bone mineral density. The aim this study was to investigate effect mechanism JGSQ pills in preventing treating postmenopausal osteoporosis. Methods Twelve-week-old SPF female SD rats (n=48) were used study. Following ovariectomy operation (n=40), randomly divided...