Haemaphysalis concinna, a three-host tick vector of several pathogens, poses high risk to the health humans and livestock. However, knowledge seasonal activities, relative density other ecological characteristics this is quite limited fragmentary. This gap represents bottleneck in our understanding risks associated with tick-borne pathogens.We conducted two-year study from April 2012 March 2014 Northern Inner Mongolia situated on China-Russia border, China, investigate activities three...

Curcumin, a natural plant extract from Curcuma longa , is known for its anti‐carcinogenic and chemopreventive effects on variety of experimental cancer models. In this study, we evaluated the curcumin elucidated mechanism in human colorectal carcinoma cells. Cell viability assay showed that significantly inhibited growth LoVo Curcumin treatment induced apoptosis accompanied by ultra‐structural changes release lactate dehydrogenase dose‐dependent manner. Moreover, with 0–30 µg/mL decreased...

Abstract Background As ectotherms that spend most of their life in the environment (off-host), ticks face challenges maintaining water balance, and some species must cope with severe low winter temperatures. Aquaporins (AQPs) are essential membrane proteins enhance cold tolerance many animals by regulating homeostatic processes. However, dynamic expressions involvement aquaporins stress remain unclear. Methods In present study, three AQP genes, HlAQP2 , HlAQP3 HlAQP5 belonging to major...

There has been increasing interest in the role of human activities disseminating antibiotic-resistance genes (ARGs) aquatic ecosystems. However, influence pollutant accumulation on anthropogenic pollutant-ARG synergistic actions is limited. This study explored association net cages with propagation pollutants and their consequences for influencing enrichment ARGs using high-throughput metagenomic sequencing. We showed that could substantially impact ecology freshwater systems by enhancing i)...

Abstract Background Glutathione S-transferases (GSTs) are a superfamily of multifunctional enzymes in living organisms with metabolic and detoxification functions, which can detoxify exogenous endogenous compounds thereby reduce the damage caused by toxic substances to body. Ticks obligate blood-sucking ectoparasites that transmit various pathogens, characterization tick-derived GSTs may help improve current understanding molecular mechanism tick resistance insecticides. In this study, novel...

The survival of overwintering ticks, is critical for their subsequent population dynamics in the spring, and consequent transmission tick-borne diseases. Survival largely influenced by severity winter temperatures degree cold hardiness at stage. bush tick Haemaphysalis longicornis, widely distributed China, can transmit various pathogens that pose serious medical/veterinary problems. In present study we investigated effect low temperature stress to survival, super-cooling point body content...

Abstract Background The tick Haemaphysalis longicornis (Neumann) is a well-known vector of numerous pathogens veterinary and medical importance. Various control strategies, including the use synthetic pesticides, have been developed to this species. However, demand for effective safe alternative pesticides increasing due adverse effects associated with intensive injudicious which include undesirable on non-target species environmental pollution. Hence, acaricidal activity extract essential...

Chemical acaricides are mainly used in traditional tick control, which leads to the emergence of resistance and concurrently results environmental pollution. In present study, chemical constituents essential oils (EOs) from Thymus mongolicus, Cinnamomum verum, Origanum vulgare was analyzed, their potential application evaluated control vector Haemaphysalis longicornis, is widely distributed over vast areas Eurasia, Australia, New Zealand. Gas chromatography-mass spectrometry analysis...

Close relationships between ticks and microbial communities are important for tick fitness pathogen colonization transmission. Haemaphysalis longicornis, distributed widely in China, can carry transmit various pathogens pose serious damages to public health economics. However, little is known about the broader array of symbionts H. longicornis under natural conditions. In present study, we investigated composition bacterial associated with evaluated putative symbionts. The eubacterial 16S...

Studies have shown chemopreventive and/or chemotherapeutic effects of several curcumin-based combinatorial treatments on colorectal cancer cells. However, their in vivo remain unclear. This study has demonstrated the therapeutic effect curcumin and oxaliplatin, alone or combination, subcutaneously xenografted LoVo human cells immunodeficient (nu/nu) mice vivo. Combinatorial administration oxaliplatin evidently inhibited growth nude mice, which was significantly more effective than either...

This paper studies the pattern and determinants of contractual projects by Chinese contractors in Africa. Contracts Africa are a dominant component China’s economic relations with They exceed foreign direct investment While similar to investments, contracts based on some different considerations are, therefore, subject from investment. work is first empirical study conducted overseas. It explores three models: economic, political, resource based. Of three, resource-based model best explains...

The important roles of microbial flora in tick biology and ecology have received much attention. Dermacentor marginatus reticulatus are known vectors various pathogens across Europe, including Slovakia. However, their bacterial microbiomes poorly explored. In this study, field-collected D. from Slovakia were characterized using 16S rRNA high-throughput sequencing. Different analyses demonstrated that the differ diversity taxonomic structures. Furthermore, species- sex-specific bacteria...

Chaos has been widely used in image encryption due to its rich properties. However, it remains an irreconcilable contradiction for security and implementation efficiency schemes. In this paper, a novel chaos-based scheme proposed, where the Lorenz chaotic system is applied generate pseudorandom sequences with good randomness, random switch control mechanism introduced ensure of scheme. Experimental results demonstrate effectiveness superiority algorithm.

is a native but endangered plant species in China, with high ornamental value and adaptability to drought cold. The relationship between the soil community structure endophytic microbes tissues of