A5056191842- Ovarian cancer diagnosis and treatment
- Inflammatory Biomarkers in Disease Prognosis
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Maternal and Perinatal Health Interventions
- Colorectal and Anal Carcinomas
- PARP inhibition in cancer therapy
- Uterine Myomas and Treatments
- Cancer, Lipids, and Metabolism
- Maternal and fetal healthcare
- Ectopic Pregnancy Diagnosis and Management
- Reproductive System and Pregnancy
- Cell death mechanisms and regulation
- Cancer Genomics and Diagnostics
- Renal cell carcinoma treatment
- Management of metastatic bone disease
- Pregnancy-related medical research
- Integrated Circuits and Semiconductor Failure Analysis
- Gynecological conditions and treatments
- Endometriosis Research and Treatment
Catholic University of Daegu
2018-2025
Daegu Catholic University Medical Center
2021-2023
ORCID
2021
Background/Objectives: This study aimed to evaluate the association between intravascular platelet aggregation in tumors and ovarian carcinoma prognosis investigate underlying mechanisms. Methods: A retrospective analysis was conducted on 144 patients with carcinoma. Immunohistochemical staining for CD42b, hypoxia-inducible factor-1α (HIF-1α), platelet-derived growth factor (PDGF), vascular endothelial (VEGF) performed using tissue microarrays assess aggregation. Staining grades ranged from...
This study investigated whether combining niraparib and trabectedin in BRCA-proficient epithelial ovarian cancer induces deficiencies ssDNA break repair dsDNA homologous recombination, leading to synthetic lethality. A2780 SKOV3 cell lines were treated with trabectedin. Cell viability was assessed using CCK-8 assays, while RT-qPCR Western blot analyzed the expression of DNA apoptosis-related genes. Apoptosis evaluated via Annexin V/PI assays. The combination therapy exhibited a synergistic...
This study aimed to compare oncological outcomes and complication rates between radical hysterectomy (RH) concurrent chemoradiotherapy (CCRT) in patients with stage IIICr cervical cancer without parametrial invasion, based on differing treatment protocols at two institutions. A total of 106 biopsy-confirmed lymph node metastasis detected pretreatment imaging, but evidence were enrolled. Of these, 55 underwent RH, while 51 received CCRT. Oncological outcomes, rates, recurrence patterns...
The purpose of this study was to investigate whether the neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte (PLR) can be used as supplementary tools differentiate between benign, borderline, malignant ovarian tumors. patients with benign borderline tumors planned 3:1:2 considering incidence each disease. Consecutive were enrolled retrospectively. Preoperative complete blood counts differentials investigated, calculated NLRs PLRs analyzed. A total 630 in study. final histopathological...
This study aimed to develop a prognosis-predicting model based on [18F]fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and clinicopathologic factors in locally advanced cervical cancer patients treated with concurrent chemoradiotherapy (CCRT). The medical records of 270 who were CCRT collected from three institutions reviewed retrospectively. A nomogram was used for predicting 2-year disease-free survival (DFS) 5-year overall (OS) Cox proportional hazards...
Abstract Aim The purpose of this study was to evaluate the prognostic factors patients with stage IIIC1r cervical cancer who underwent concurrent chemoradiotherapy. Methods A total 134 treated chemoradiotherapy for pelvic and/or paraaortic lymph node metastasis (PALNM) were enrolled in study. Clinical variables investigated through review patients' medical records. Results 5‐year overall survival (OS) rate IIICr 70.5%. Age, PALNM, parametrial invasion, T stage, side wall differentiation,...
Background and Objectives: Menorrhagia is defined as a blood loss of more than 80 mL, which significant enough to cause anemia. Previously known methods for evaluating menorrhagia, such the alkalin-hematin method, pictograms, measuring weight sanitary products, were all impractical, complex, time-consuming. Therefore, this study aimed determine item among menstrual history taking was most associated with menorrhagia devised simple method through that can be applied clinically. Materials...
: Long and ineffective labor causes hardships for mothers doctors increases the rate of cesarean sections medical comorbidities. Several factors contribute to effective less painful labor, including maternal age, parity, fetal characteristics, medications or procedures that obstetricians use labor. We aimed study affect duration identify those make more effective.
Background: The purpose of this study was to investigate whether the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte (PLR) can be used as supplemental tools differentiate between uterine myomas sarcomas. Methods: From January 2000 May 2020, patients diagnosed with sarcoma or myoma after surgery at Catholic University Hospital Daegu were enrolled in study. age preoperative hematologic findings including hemoglobin, white blood cell count, neutrophils, lymphocytes, platelet...
This study investigated the association between maximum standardized uptake values (SUVmax) on preoperative 18-FDG PET-CT and next-generation sequencing (NGS) results in post-surgical ovarian malignant tissue patients with advanced cancer. Twenty-five stage IIIC or IV cancer who underwent both postoperative NGS for malignancies were retrospectively enrolled. Two had no detected variants, 21 of 23 any somatic variant at least one single nucleotide (SNV) insertion/deletion (indel), 10 showed...
<h3>Introduction</h3> In 2009 International Federation of Gynecology and Obstetrics (FIGO) staging, patients with stage IB or IIA lymph node metastasis (LNM) underwent operation concurrent chemoradiation (CCRT). However, in revised 2018 FIGO LNM were IIIC have been CCRT. The purpose study was to compare outcome CCRT IIIC. <h3>Methods</h3> Total 106 treated either surgical treatment for cervical cancer pelvic and/or paraaortic enrolled retrospectively study. confirmed by radiologically...
Abstract Background: The purpose of this study was to investigate whether neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte (PLR) can be supplementary tools differentiate benign, borderline, malignant ovarian tumors. Methods: This retrospective reviewed the postoperative histopathology in patients with tumors (220 59 228 malignant). White blood cell, platelet, neutrophil lymphocyte counts, percentage neutrophils lymphocytes, calculated NLR PLR were analyzed between groups using...