A5042328089- Reconstructive Surgery and Microvascular Techniques
- Organ and Tissue Transplantation Research
- Organ Donation and Transplantation
- Trauma and Emergency Care Studies
- Bone fractures and treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hip and Femur Fractures
- Wound Healing and Treatments
- Surgical Sutures and Adhesives
- Transplantation: Methods and Outcomes
- Trauma Management and Diagnosis
- Surgical site infection prevention
- Cleft Lip and Palate Research
- Pelvic and Acetabular Injuries
- Orthopedic Surgery and Rehabilitation
- Traumatic Ocular and Foreign Body Injuries
- Lymphatic System and Diseases
- Craniofacial Disorders and Treatments
- Tracheal and airway disorders
- Organ Transplantation Techniques and Outcomes
- Diagnosis and Treatment of Venous Diseases
- Burn Injury Management and Outcomes
- Body Contouring and Surgery
- COVID-19 and healthcare impacts
- Vagus Nerve Stimulation Research
The University of Texas Health Science Center at San Antonio
2023-2025
The University of Texas Health Science Center at Houston
2024-2025
University of Oxford
2019-2020
Nuffield Orthopaedic Centre
2020
Oxford University Hospitals NHS Trust
2019-2020
John Radcliffe Hospital
2019-2020
United States Army Institute of Surgical Research
2013-2019
Chang Gung University
2019
Chang Gung Memorial Hospital
2019
Taoyuan Chang Gung Memorial Hospital
2018
The aim of this study was to report the pattern severe open diaphyseal tibial fractures sustained by military personnel, and their orthopaedic–plastic surgical management.The United Kingdom Military Trauma Registry searched for all such between 2006 2010. Data were gathered on demographics, injury, management preliminary outcome, with 49 patients 57 identified in-depth study. median total number orthopaedic plastic procedures per limb three (2 8). Follow-up 12 months complete in 52 tibiae...
The aim of this study was to characterise severe open tibial shaft fractures sustained by the UK military personnel over 10 years combat in Iraq and Afghanistan. Joint Theatre Trauma Registry searched for all such injuries, clinical records were reviewed patients. One hundred Gustilo-Anderson III tibia 89 patients identified year period; majority injuries through explosive weapons (63, 68 %) with remainder being injured from gunshot wounds. Three not followed up 12 months therefore excluded....
Vascularized submental lymph node flap transfer to the wrist is an effective treatment for breast cancer-related lymphedema. Dorsal placement was hypothesized offer superior outcomes due favorable venous drainage; however, more visible in this position compared with volar side and a cosmetic concern patients. This study response of lymphedema vascularized flaps at wrist, between dorsal recipient sites.A retrospective longitudinal examined 15 patients receiving performed by single surgeon...
Summary: When squamous cell carcinoma necessitates mandibular resection, the resultant defect can be complex. An osteocutaneous fibula free flap is an effective reconstruction option, typically supplied by peroneal artery for both and skin flap. In this case report, anatomical variation was found: paddle soleus musculocutaneous perforators of posterior tibial artery, whereas artery. The perforator vessels from were anastomosed to distal end vessels. left superior thyroid a branch internal...
Background: The potential of artificial intelligence (AI) to support physician evidence-based medicine is vast. We compared AI’s ability perform a systematic review the literature that human investigators. Negative-pressure wound therapy (NPWT), mainstay management with large but varied body evidence, was therefore chosen as subject this investigation. Producing high-level evidence NPWT’s impact on healing has been challenging due trial design issues, making important and challenging. In...
Background Currently, patients receiving vascularized composite allotransplantation (VCA) grafts must take long-term systemic immunosuppressive therapy to prevent immunologic rejection. The morbidity and mortality associated with these medications is the single greatest barrier more being able receive life-enhancing transplants. In contrast solid organs, VCA, exemplified by hand or face transplants, allow visual diagnosis of clinical acute rejection (AR), directed biopsy targeted graft...
Background: Patient-reported outcome measures are an important metric in evaluating treatment efficacy of reconstructive surgery. Toe-to-hand transfer can restore vital prehensile function; however, this surgery is complex, extensive rehabilitation required, and there concerns about donor-site morbidity. This study longitudinally explores the benefits procedure, from patient’s perspective, using patient-reported measures. Methods: Twenty-three patients who underwent free toe-to-hand...
Devastating extremity injuries are prevalent but often survivable on the modern battlefield. These complex require advanced methods of reconstruction, involving prolonged ischemic periods and reperfusion injury. Using our group's validated porcine model gracilis myocutaneous flap transplantation, this study demonstrates that an interim perfusion hydrogen sulfide (H2S) mitigates effects injury in setting delayed restoration blood flow.A (200-400 g; surface area, 250 cm²) was procured from...
Free tissue transfer is a powerful reconstructive surgical technique. The ischemia reperfusion injury (IRI) at revascularization affects the flap and patient; reducing this insult could improve outcomes. This study evaluated effect of C1 esterase inhibitor (C1-inh) on IRI in porcine musculocutaneous model.A was transferred from limb to neck 12 swine. Flaps underwent 3-hour ischemic interval prior revascularization. Intervention group flaps (n = 6) were perfused intra-arterially with 100U...
Abstract Purpose Deferring cancer surgery can have profound adverse effects including patient mortality. During the COVID-19 pandemic, departmental reorganisation and adherence to evolving guidelines enabled provision of uninterrupted surgical care patients with bone soft tissue tumours (BST) in need surgery. We reviewed outcomes surgeries on BST during first two months pandemic at one tertiary centres UK. Materials methods Between 12 March 2020 May 2020, 56 a median age 57 years (18–87)...
Background: The restoration of complex tissue deficits with vascularized composite allotransplantation is a paradigm shift in reconstructive surgery. Clinical adoption limited by the need for systemic immunosuppression, associated morbidity and mortality. Small-animal models lack biological fidelity preclinical relevance to enable translation immunologic insights humans. Large-animal have been described; however, limitations persist, including inability heterotopic evaluate functional nerve...