A5101775425- Dental materials and restorations
- Oral microbiology and periodontitis research
- Bone Tissue Engineering Materials
- Dental Erosion and Treatment
- Dental Health and Care Utilization
- Bone and Dental Protein Studies
- Endodontics and Root Canal Treatments
- Dental Implant Techniques and Outcomes
- Dental Radiography and Imaging
- Dental Anxiety and Anesthesia Techniques
- Dental Trauma and Treatments
- Graphene and Nanomaterials Applications
- Nanoplatforms for cancer theranostics
- Dental Research and COVID-19
- Laser Applications in Dentistry and Medicine
- Periodontal Regeneration and Treatments
- Salivary Gland Disorders and Functions
- Nanoparticle-Based Drug Delivery
- Dendrimers and Hyperbranched Polymers
- Phytochemicals and Antioxidant Activities
- Inflammasome and immune disorders
- Essential Oils and Antimicrobial Activity
- Supramolecular Self-Assembly in Materials
- Kawasaki Disease and Coronary Complications
- Streptococcal Infections and Treatments
Sichuan University
2016-2025
State Key Laboratory of Oral Diseases
2014-2025
Chengdu University
2015-2019
Stomatology Hospital
2016-2017
National Clinical Research
2017
University of Dental Medicine
2015
University of Amsterdam
2014
Academic Center for Dentistry Amsterdam
2014
This review focuses on the relationship between structures and properties of various polymers for different applications in dentistry.
During caries formation, dental biofilms function not only as acid producers but also reservoirs and diffusion barriers for active caries-preventive components. The aim of this study was to investigate the influence a stagnant layer on efficacy NaF nano-hydroxyapatite (nHA). Biofilms Streptococcus mutans C180-2 were formed surfaces artificially demineralized enamel in an attachment biofilm model. After 2 days model subjected pH-cycling schedule, together with control group without biofilms....
The remineralization of demineralized dentin with biomimetic templates is great interest in the fields material science and stomatology. Amine‐terminated PAMAM dendrimer (PAMAM‐NH 2 ), which possesses a highly ordered architecture many calcium coordination sites, may be desirable template for inducing remineralization. In this study, effect third generation PAMAM‐NH (G3‐PAMAM‐NH ) on investigated. Demineralized samples are treated G3‐PAMAM‐NH solution (1 mg · mL −1 then immersed artificial...
Dentin phosphoprotein (DPP) plays an extremely important role in the biomineralization of human tooth. The repetitive nucleotide sequence aspartate-serine-serine (DSS) is fundamental unit within DPP, and peptides containing 8 repeats DSS (8DSS) have been shown to possess ability induce remineralization demineralized enamel. In this work, we coated 8DSS peptide on completely dentin evaluate effect coating remineralization. Human samples were with 37% phosphoric acid for 2 min, then (1 mg...
The aim of this study was to examine the dentin remineralization extent that poly(amido amine) (PAMAM) induces quantitatively, and select most effective kind PAMAM with a certain terminal group for remineralization, both first time.
Infectious bone defects are characterized by the partial loss or destruction of tissue resulting from bacterial contaminations subsequent to diseases external injuries. Traditional transplantation and clinical methods insufficient in meeting treatment demands for such diseases. As a result, researchers have increasingly focused on development more sophisticated biomaterials improved therapeutic outcomes recent years. This review endeavors investigate specific reparative materials utilized...
Kawasaki disease (KD) primarily affects children as an acute systemic vasculitis. Numerous studies indicated elevated risk of cardiovascular due to metabolic disturbances. Despite this knowledge, the specific modes involved in KD remain unclear. We examined metabolome individuals with 108 and 52 non-KD controls (KD vs. nKD) by ultraperformance liquid chromatography (UPLC) tandem mass spectrometry (MS). Differential analysis uncovered disturbed production bile acids lipids KD. Furthermore, we...
Abstract Tea polyphenols (TP) are not only potent antimicrobial and antioxidant agents but also effective modifiers in the formation of nanosized crystals. Since nano‐hydroxyapatite (n‐HA) is known to enhance remineralization dental hard tissue, our aims were synthesize calcium phosphate particles incorporating TP test their potential as caries preventive agent. An ammonia water diffusion method was used (TP‐CaP) presence various amounts TP. The resultant products characterized by scanning...
Homeostasis of oral microbiota can be maintained through microbial interactions. Previous studies showed that Streptococcus oligofermentans, a non-mutans streptococci frequently isolated from caries-free subjects, inhibited the cariogenic mutans by production hydrogen peroxide (HP). Since pH is critical factor in caries formation, we aimed to study influence on competition between S. oligofermentans and biofilms. To this end, were inoculated alone or mixed at 1:1 ratio buffered biofilm...
Fluoride agents hold promise for the repair and prevention of caries lesions, but their interaction with enamel is often hampered diminished because dynamic wet environment in oral cavity, which affects efficacy fluoride delivery limits treatment success. We herein developed a mussel-inspired adhesive system (denoted TS@NaF) fabricated by self-assembly tannic acid (TA), silk fibroin (SF), sodium (NaF). TS@NaF demonstrated remarkable biological stability biocompatibility, showed reliable...
Photothermal therapy (PTT) encounters challenges of rapid thermal loss and potential tissue damage. In response, we propose a Heat-Boost Lock implant coating strategy inspired by the adaptation biological membranes, enabling precise local photothermal utilization. This incorporates poly(tannic acid) (pTA) bridging layer on implants, facilitating stable layer-by-layer integration black phosphorus (BP) top cell membrane layer. The significantly curtails (extending heat retention 17.62%) stores...
Remineralization and reduction of cariogenic bacteria at the tooth surface are effective ways to treat dental caries.
The targeted delivery of therapeutic drugs into cancer cells is a facile method to improve efficacy.
Abstract Objectives Bisphosphonate‐related osteonecrosis of the jaw (BRONJ) is a severe complication systemic nitrogen‐containing bisphosphonate (N‐BP) administration, which leads to osteonecrosis, pain, and infection. Despite much effort, effective remedies are yet be established. This study aimed investigate potential recovery effect borate bioactive glass (BBG) in vitro vivo. Methods The BBG on zoledronate‐treated bone marrow mesenchymal cells (BMSCs) human umbilical vein endothelial...
Lack of antibacterial properties and poor bioactivity implants' surfaces will increase the risk implant-associated infections osseointegration, subsequently leading to implant failure. In present study, an organic–inorganic coating with anti-infection osteogenesis was constructed on titanium (Ti) implants enhance osseointegration. Inspired by mussel, tannic acid (TA) abundant catechol groups chosen as a bonding medium combine inorganic hydroxyapatite nanoparticles (nHA) organic polyethylene...