A5101650236- Wound Healing and Treatments
- Atrial Fibrillation Management and Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Cardiac Ischemia and Reperfusion
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Nanoplatforms for cancer theranostics
- Organ Transplantation Techniques and Outcomes
- Surgical Sutures and Adhesives
- Cardiac Valve Diseases and Treatments
- Intensive Care Unit Cognitive Disorders
- RNA regulation and disease
- Brain Metastases and Treatment
- Dielectric materials and actuators
- Nerve injury and regeneration
- Transplantation: Methods and Outcomes
- Conducting polymers and applications
- Cardiac Structural Anomalies and Repair
- Ocular Oncology and Treatments
- Pericarditis and Cardiac Tamponade
- Lung Cancer Treatments and Mutations
- Kawasaki Disease and Coronary Complications
- Mitochondrial Function and Pathology
- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
Sichuan University
2017-2024
West China Hospital of Sichuan University
2019-2024
China Medical University
2022
Lanzhou University
2021-2022
Dalian Medical University
2022
Conductive hydrogel sensors have attracted attention for use in human motion monitoring detection, but integrating excellent biocompatibility, mechanical, self-adhesive, and self-healing properties, high sensitivity into a remains challenge.
Burn trauma is generally associated with profound inflammation and organ injuries, especially the lung. Damage-associated molecular patterns (DAMPs), such as mitochondrial DNA (mtDNA), released after tissue play a crucial role in development of inflammation. The aim our study was to investigate protective profiles cyclosporine-A (CsA) murine models thermal injury. We studied 24 C57BL/6 mice which were randomly subjected four groups: sham-operation group (SO group, n = 6), an experiment (a...
Developing a self-healing hydrogel wound dressing with intrinsic antibacterial and on-demand dissociable properties is highly desired yet challenging in clinician applications to enhance angiogenesis collagen growth for rapid healing. Herein, we present thermoresponsive antimicrobial property based on poly(N-isopropylacrylamide)-derived ABA triblock copolymer (TNOTN) an aldehyde β-cyclodextrin (ACD) healing of full-thickness infected wounds. The prepared TNOTN–ACD exhibits excellent thermal...
In recent years, colchicine has been used to reduce the risk of cardiovascular events; in particular, it effectively for treatment atrial fibrillation (AF). We first discovered that can treat AF a rat model and reverse effects fibrosis. To illustrate potential therapeutic mechanism against AF, we performed comparative transcriptome analyses; our aim was elucidate so as improve prognoses AF. Genomics bioinformatics analyses revealed IL-17 signaling pathway, renin secretion pathway are...
In order to explore the possible mechanism of curcumin in treatment AF, we focused on myocardial fibrosis pathogenesis atrial fibrillation whether could play a role AF by reducing fibrosis.Rats were given daily gavage saline (control and groups) or (4 mL/kg, concentration: 50 mg/mL, during days 4–28. The rat model was induced Ach - CaCl2, evaluate therapeutic effect duration rhythm, degree secretion inflammatory factors serum. RNA-seq alleviating AF. significantly inhibits reduces left...
Lungs are easily damaged by the inflammatory responses induced after extensive burns. The aim here was to investigate protective role of epigallocatechin gallate (EGCG) in mitochondrial DNA (mtDNA)-mediated and acute respiratory distress syndrome (ARDS) a rat model thermal injury. Male Sprague-Dawley rats were randomly assigned five groups. In first experiment, full-thickness injury or control procedure, covering 30% TBSA, inflicted on three groups designated as injury, EGCG, sham second...
BACKGROUND Lipopolysaccharide (LPS) is generally associated with sepsis, which causes multiple system injuries and systemic inflammatory response. Mitochondrial DNA (mtDNA) of great importance in mediation inflammation. The aim this study was to investigate the protective profiles Cyclosporine-A (CsA) LPS-induced acute lung injury (ALI) inflammation by inhibition mtDNA Toll-like receptor. MATERIAL AND METHODS Twenty-four C57BL/6 mice were randomly assigned 4 groups: a sham group (n=6); an...
BACKGROUND Lung ischemia/reperfusion injury (LIRI) is a medical problem featuring pulmonary dysfunction and damage. The present study aimed to investigate the protective effects of erythropoietin (EPO), which has been reported be an anti-inflammatory agent, on LIRI through inhibiting TLR-4/NF-κB signaling pathway. MATERIAL AND METHODS All rats were randomly divided into 3 groups (n=8): control group, vehicle+LIRI EPO+LIRI group. included 90-min ischemia 120-min reperfusion, while RhEpo was...
1. Wańkowicz P, Nowacki Gołąb-Janowska M. (2019). Risk factors for ischemic stroke in patients with non-valvular atrial fibrillation and therapeutic international normalized ratio range Arch Med Sci. 15: 1217-22. Google Scholar
Carbon ion therapy (CIT) is a form of particle therapy, which not only spares normal tissues but may also improve local control recurrent intracranial tumours. Cerebral radiation necrosis (RN) one the most serious adverse reactions brain tumours following reirradiation, lead to neurological decline or even death. Bevacizumab an anti‑vascular endothelial growth factor antibody, has been used treat symptomatic RN. However, studies on bevacizumab for treatment CIT‑induced RN are sparse. The...
The occurrence of a giant ruptured aneurysm originating from the noncoronary sinus Valsalva in right atrium is extremely rare. Herein, case presented (SVA) that was protruding into atrium, which almost completely occupied by an aneurysm. A 61-year-old female referred to hospital for exertional palpitation and dyspnea. While surgical repair performed resection remodeling with patch fresh bovine pericardium, very rare observed. It difficult distinguish coronary also believed various imaging...
Abstract Background: To investigate the characteristics of sleep cycle in children with severe acute bronchopneumonia treated invasive mechanical ventilation at different sedation depths. Methods： We included 35 pediatric patients using Pediatric Intensive Care Unit Shengjing Hospital China Medical University. They were divided into deep group (n=21; ramsay score 5-6) and light (n=14; score3-4) based on depth achieved during ventilation. Long-term video electroencephalography (EEG)...
Tricuspid valve replacement is becoming more and popular at various medical centres due to the increase in numbers of patients with tricuspid regurgitation. We report on a case 59-year-old man who had undergone preservation native leaflets two years earlier, developed early prosthetic dysfunction, which may have been caused by fusion leaflets. The experience this informs us that preserving subvalvular apparatus impede motion prosthesis, adapting individual morphology during could benefit...