A5047526729- Nutrition and Health in Aging
- Enhanced Recovery After Surgery
- Cancer survivorship and care
- Cardiac, Anesthesia and Surgical Outcomes
- Frailty in Older Adults
- Lung Cancer Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Hip and Femur Fractures
- Colorectal Cancer Surgical Treatments
- Cardiac Health and Mental Health
- Head and Neck Cancer Studies
- COVID-19 Clinical Research Studies
- Esophageal and GI Pathology
- Bladder and Urothelial Cancer Treatments
- Delphi Technique in Research
- Respiratory Support and Mechanisms
- Cancer, Stress, Anesthesia, and Immune Response
- Fiscal Policies and Political Economy
- Long-Term Effects of COVID-19
- Plant-based Medicinal Research
- Sepsis Diagnosis and Treatment
- Stoma care and complications
- Immune cells in cancer
- Hemodynamic Monitoring and Therapy
- Dysphagia Assessment and Management
Dompé (Italy)
2022-2024
McGill University
2016-2024
McGill University Health Centre
2016-2024
University of Rome Tor Vergata
2021-2024
European Investment Bank
2024
Montreal General Hospital
2018-2023
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2021
Istituti di Ricovero e Cura a Carattere Scientifico
2021
Vita-Salute San Raffaele University
2021
University of Milan
2016-2018
Research supports use of prehabilitation to optimize physical status before and after colorectal cancer resection, but its effect on postoperative complications remains unclear. Frail patients are a target for interventions owing increased risk poor outcomes.To assess the extent which program affects 30-day in frail undergoing resection compared with rehabilitation.This single-blind, parallel-arm, superiority randomized clinical trial recruited from September 7, 2015, through June 19, 2019....
Preserving functional capacity is a key element in the care continuum for patients with esophagogastric cancer. Prehabilitation, preoperative conditioning intervention aiming to optimize physical status, has not been tested upper gastrointestinal surgery date.
Colorectal cancer (CRC) is the second most prevalent type of in world. Surgery only curative option. However, postoperative complications occur up to 50% patients and are associated with higher morbidity mortality rates, lower health related quality life (HRQoL) increased expenditure care. The number severity closely preoperative functional capacity, nutritional state, psychological smoking behavior. Traditional approaches have targeted period for rehabilitation lifestyle changes. recent...
Importance Colorectal surgery is associated with substantial morbidity rates and a lowered functional capacity. Optimization of the patient’s condition in weeks prior to may attenuate these unfavorable sequelae. Objective To determine whether multimodal prehabilitation before colorectal cancer can reduce postoperative complications enhance recovery. Design, Setting, Participants The PREHAB randomized clinical trial was an international, multicenter conducted teaching hospitals implemented...
Multimodal prehabilitation is a preoperative conditioning intervention in form of exercise, nutritional assessment, whey protein supplementation, and anxiety-coping technique. Despite recent evidence suggesting that could improve functional capacity patients undergoing colorectal surgery for cancer, all studies were characterized by relatively small sample size. The aim this study was to confirm what previously found three population trials.Data 185 participants enrolled pilot single group...
Background: Prehabilitation has been previously shown to be more effective in enhancing postoperative functional capacity than rehabilitation alone. The purpose of this study was determine whether a weekly supervised exercise session could provide further benefit our current prehabilition program, when comparing standard post-surgical rehabilitation.Methods: A parallel-arm single-blind randomized control trial conducted patients scheduled for non-metastatic colorectal cancer resection....
Objective: The objective of this study was to investigate the effect prehabilitation on survival after colorectal cancer surgery. Summary Background Data: Preoperative multimodal exercise and nutritional programs (prehabilitation) improve functional capacity recovery following Exercise may also affect outcomes by mediating systemic inflammatory response. is unknown. Methods: Pooled data from 3 trials (2 randomized controlled trials, 1 cohort) in patients undergoing elective, biopsy-proven,...
BACKGROUND Multimodal prehabilitation, including exercise training, nutritional therapy and anxiety reduction, has been shown to attenuate functional decline associated with surgery. Due the growing interest in status as a targeted surgical outcome, better understanding of optimal prescription is critical. OBJECTIVE The objective compare peri-operative trajectory response two different training protocols within 4-week, supervised, multimodal prehabilitation programme. DESIGN This was single...
Chronic neuropathic pain (NP) is an increasingly prevalent disease and leading cause of disability which challenging to treat. Several distinct classes drugs are currently used for the treatment chronic NP, but each drug targets only narrow components underlying pathophysiological mechanisms, bears limited efficacy, comes with dose-limiting side effects. Multimodal therapies have been proposed as potential therapeutic approaches target multiple mechanisms nociceptive transmission modulation....
Background: Poor functional capacity (FC) is an independent predictor of postoperative morbidity. However, there still a lack evidence as to whether enhancing FC before surgery has protective effect on complications. The purpose this study was determine improvement in preoperative impacted positively surgical morbidity.Methods: This secondary analysis cohort patients who underwent colorectal resection for cancer under Enhanced Recovery After Surgery care. assessed with the 6-min walk test,...
Background Exercise training is a component of the pre‐habilitation program. While in one previous study was home‐based, subsequent investigation it supervised hospital. The hypothesis this secondary analysis two studies to determine whether exercise further accelerates return baseline walking ability. Methods Data from consecutive randomized control trials (RCT) comparing rehabilitation cancer patients scheduled for colorectal surgery were pooled analysis. interventions similar and included...
Depression and poor functional status (FS) frequently co-occur. Though both predict adverse surgical outcomes, research examining preoperative performance (FP; self-reported) capacity (FC; performance-based) measures in depressed cancer patients is lacking. Prehabilitation, a intervention including exercise, nutrition, stress-reduction, may improve FC; however, whether benefit from this remains unknown. The primary objectives were to (a) assess differences FP FC (b) explore the impact of...
We construct a new indicator of de facto financial integration for the EU. The resulting is pro-cyclical as it evolves along cyclical pattern economic activity in European Union. It then appended to set relevant and macroeconomic variables, within FAVAR framework, allow us separate impact boom-bust shocks from structural shocks. Increasing tends improve risk absorption reduce income disparities among countries. However, our analysis suggests that most movements reflect business cycle...
Optimal perioperative care envisages a multidisciplinary and integrated medical from the moment of contemplation surgery until patient-defined recovery. From patient perspective, collaborative approach, shared care, behavioral changes are reasonable expectations as part centered care. Although might be technically successful, significant proportion vulnerable high-risk patients who undergo do not meet timely patient-oriented outcomes recovery, such return to their preoperative muscle...