- Carbohydrate Chemistry and Synthesis
- Global Cancer Incidence and Screening
- Blockchain Technology Applications and Security
- Diabetes Treatment and Management
- Caveolin-1 and cellular processes
- Liver Disease Diagnosis and Treatment
- Biometric Identification and Security
- Multi-Criteria Decision Making
- Dendrimers and Hyperbranched Polymers
- RNA and protein synthesis mechanisms
- Fixed Point Theorems Analysis
- User Authentication and Security Systems
- Breast Cancer Treatment Studies
- Chemical Synthesis and Analysis
- Shoulder Injury and Treatment
- Asymmetric Synthesis and Catalysis
- Face and Expression Recognition
- Metabolism, Diabetes, and Cancer
- Phytochemical compounds biological activities
- Glycosylation and Glycoproteins Research
- MicroRNA in disease regulation
- Signaling Pathways in Disease
- Advanced Steganography and Watermarking Techniques
- Robotics and Automated Systems
- Natural Antidiabetic Agents Studies
Invertis University
2022-2025
University of Michigan
2025
University of Oklahoma Health Sciences Center
2021-2024
National Institute Of Technology Silchar
2022-2024
The University of Texas Health Science Center at Houston
2024
Southern University and Agricultural and Mechanical College
2017-2024
Pennington Biomedical Research Center
2023-2024
Teerthanker Mahaveer University
2024
The University of Texas Southwestern Medical Center
2024
Louisiana State University
2022-2024
PEGylation typically improves the systemic exposure and tumor biodistribution of polymeric drug delivery systems, but may also restrict enzyme access to peptide-based linkers. The impact dendrimer generation (G4 vs G5) PEG length (570 1100 Da) on pharmacokinetics, biodistribution, release kinetics, anticancer activity a series PEGylated polylysine dendrimers conjugated with doxorubicin via cathepsin-B cleavable valine-citrulline linker was therefore investigated in rodents. Although smallest...
Both cholesterol (Cho) and methionine (Met, a precursor for homocysteine) are risk factors fatty liver disease. Since Western diets rich in Cho Met, we investigated the hepatic effects of feeding diet enriched Met Cho. Further, based on reported anti-oxidative lipid lowering properties sitagliptin (an antidiabetic drug), tested whether it could counteract negative high Met. We therefore hypothesized that would ameliorate development pathology is produced by either Cho, or both.Male Sprague...
Abstract: Cardiovascular diseases remain a significant reason for illness and death globally. Although certain interleukins have been extensively researched about cardiovascular disease (CVD), new findings identified unique members of the interleukin family that could potentially play role in well-being ailments. This review discusses current understanding these recently interleukins, such as IL-27, IL-31, IL-32, IL-33, IL-28 group (IL-28A, IL-28B, IL-29), development diseases. Every has...
Objective Glenohumeral (GH) osteoarthritis (OA) is the third most common large joint disease, after hip and knee OA. This study aimed to identify risk factors for GH Methods We used data from Dallas Shoulder cohort, including individuals aged 40–85. Those with confirmed OA based on X-ray were cases, those without controls. Univariate, least absolute shrinkage selection operator multivariate analyses identified factors, age, body mass index (BMI), sex, work-related shoulder problems,...
The integration of AI into the design industry is transforming image generation with novel creative opportunities, alongside new difficulties for designers. This research analyses effects emerging artificial intelligence trends on user interface (UI) and experience (UX) growing role designer in an AI-enhanced workflow. development generative adversarial networks (GANs) image-to-text programs such as DALL·E Stable Diffusion has led to sophisticated personalized virtual imagery. These...
Increased breast cancer (BC) mortality risk posed by delayed surgical resection of tumor after diagnosis is a growing concern, yet the underlying mechanisms remain unknown. Our cohort analyses early-stage BC patients reveal emergence significantly rising when biopsy-to-surgery interval was extended beyond 53 days. Additionally, histology post-biopsy tumors shows prolonged retention metastasis-permissive wound stroma dominated M2-like macrophages capable promoting cell...
Abstract The 2‐amino‐2‐deoxy‐ α ‐ D ‐glucopyranosyl moiety (ring I) of paromomycin was replaced by a 2,4‐diamino‐2,4‐dideoxy‐ ‐glucopyranosyl, ‐galactopyranosyl, or 3,4,5‐trideoxy‐4‐aza‐ erythro ‐heptoseptanosyl to investigate the effect substituent at C(4′) on interaction with ribosomal RNA. triflate 6 prepared from key intermediate pentaazido 3′,6′‐dibenzyl ether 5 , and hexosulose 10 obtained oxidation Dess – Martin 's periodinane. Stereoselective reduction NaBH 4 gave alcohol 11 that...
Substantial evidence indicates that delay of first treatment after diagnosis is associated with poorer survival outcomes in breast cancer. Accordingly, the Commission on Cancer introduced a quality measure for receipt therapeutic surgery within 60 days diagnostic biopsy stage I-III cancer patients non-neoadjuvant setting. It unknown, however, what may contribute to mortality delay. Therefore, we investigated whether type moderates effect risk posed by delay.Retrospective analysis 31,306...