A5002429861- Heparin-Induced Thrombocytopenia and Thrombosis
- Platelet Disorders and Treatments
- SARS-CoV-2 and COVID-19 Research
- Blood groups and transfusion
- Complement system in diseases
Sapienza University of Rome
2022-2023
A rapid immune response is critical to ensure effective protection against COVID-19. Platelets are first-line sentinels of the vascular system able rapidly alert and stimulate system. However, their role in vaccines not known.To identify features platelet-immune crosstalk that would provide an early readout vaccine efficacy adults who received mRNA-based COVID-19 (BNT162b2).We prospectively enrolled 11 young healthy volunteers (54% females, median age: 28 years) two doses BNT162b2, 21 days...
BackgroundGenetic-based COVID-19 vaccines have proved to be highly effective in reducing the risk of hospitalization and death. Because they were first distributed a large-scale population, adenoviral-based linked very rare thrombosis with thrombocytopenia syndrome, interplay between platelets vaccinations increasingly gained attention.ObjectivesThe objective this article was study crosstalk vaccine-induced immune response.MethodsWe prospectively enrolled young healthy volunteers who...