A5091458962- Oral and Maxillofacial Pathology
- Head and Neck Surgical Oncology
- Bone Tumor Diagnosis and Treatments
- Ear and Head Tumors
- Cancer Diagnosis and Treatment
- Brain Metastases and Treatment
- Cancer Cells and Metastasis
- Management of metastatic bone disease
- Bone health and treatments
- dental development and anomalies
- Metastasis and carcinoma case studies
Universidade de São Paulo
2021-2025
Squamous cell carcinoma is the most common cancer of oral cavity. When tumor invades bone tissue, prognostic and survival rates decrease a lot, treatment becomes more aggressive, with several damages to patient health system. Many molecular mechanisms invasion process are not understood yet, but it already known that one central processes evolution - adjacent tissues metastasis large spectrum phenotypic changes in epithelial cells mesenchymal, named as epithelial-mesenchymal transition...
Bone invasion is an important prognostic factor in oral squamous cell carcinoma, leading to a lower survival rate and the use of aggressive treatment approaches. Epithelial-mesenchymal transition (EMT) possibly involved this process, because it often related mechanisms motility invasiveness. This study examined whether panel epithelial-mesenchymal markers are present cases carcinoma with bone these proteins have any relationship patients' clinical-pathological parameters factors....