A5025407896- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Pediatric Hepatobiliary Diseases and Treatments
- Renal Transplantation Outcomes and Treatments
- Intestinal Malrotation and Obstruction Disorders
- Childhood Cancer Survivors' Quality of Life
- Dialysis and Renal Disease Management
- Central Venous Catheters and Hemodialysis
- Gallbladder and Bile Duct Disorders
- Appendicitis Diagnosis and Management
- Clinical Nutrition and Gastroenterology
- Cytomegalovirus and herpesvirus research
- Esophageal and GI Pathology
- Pleural and Pulmonary Diseases
- Viral-associated cancers and disorders
- Intestinal and Peritoneal Adhesions
- Adolescent and Pediatric Healthcare
- Family and Disability Support Research
- Congenital Diaphragmatic Hernia Studies
- Muscle and Compartmental Disorders
- Transplantation: Methods and Outcomes
- Congenital Anomalies and Fetal Surgery
- Gastrointestinal disorders and treatments
- Abdominal Surgery and Complications
- Hepatocellular Carcinoma Treatment and Prognosis
University of Missouri–Kansas City
2000-2025
Children's Mercy Hospital
2011-2021
Mercy Hospital
2007-2018
Montreal Children's Hospital
2011
McGill University
2011
Saskatoon Medical Imaging
2011
Pediatric Oncology Group
2004
Children's Medical Center
1988-2003
Baylor University Medical Center
2001
The University of Texas Southwestern Medical Center
1991-2000
In Brief Background: Laparoscopic appendectomy through a single umbilical incision is an emerging approach supported by several case series. However, to date, prospective comparative data are lacking. Therefore, we conducted prospective, randomized trial comparing site laparoscopic 3-port appendectomy. Methods: After Internal Review Board approval, patients were via or standard access. The primary outcome variable was postoperative wound infection. Using power of 0.9 and alpha 0.05, 180...
Pyloric stenosis, the most common surgical condition of infants, is treated by longitudinal myotomy pylorus. Comparative studies to date between open and laparoscopic pyloromyotomy have been retrospective report conflicting results. To scientifically compare 2 techniques, we conducted first large prospective, randomized trial approaches.After obtaining IRB approval, subjects with ultrasound-proven pyloric stenosis were either or pyloromyotomy. Postoperative pain management, feeding schedule,...
Late graft loss (LGL) and late mortality (LM) following liver transplantation (LT) in children were analyzed from the studies of pediatric (SPLIT) database. Univariate multivariate associations between pre‐ postoperative factors LGL LM 872 patients alive with their primary allografts 1 year after LT reviewed. Thirty‐four subsequently died 35 underwent re‐LT (LGL). Patients who survive first posttransplant had 5‐year patient survival rates 94.2% 89.2%, respectively. Graft was caused by...
The efficacy of irrigating the peritoneal cavity during appendectomy for perforated appendicitis has been debated extensively. To date, prospective comparative data are lacking. Therefore, we conducted a prospective, randomized trial comparing irrigation to suction alone laparoscopic in children.Children younger than 18 years with were minimum 500 mL normal saline, or only appendectomy. Perforation was defined as hole appendix fecalith abdomen. primary outcome variable postoperative abscess....
The experience with laparoscopic cholecystectomy in children trails the adult numbers and remains underreported. Therefore, we reviewed our this approach.A retrospective review of most recent 6-year at Children's Mercy Hospital (Kansas City, MO) between September 5, 2000, June 1, 2006, was performed. Data points included patient demographics, indication for operation, operative time, complications, recovery.During study period, 224 patients underwent a cholecystectomy. mean age 12.9 years...
Though robust clinical data are available within transplantation, these not used for broad-based, multicentered quality improvement initiates. This article describes a targeted initiative the Studies of Pediatric Liver Transplantation (SPLIT) Registry. Using standard statistical techniques and expertise to adjust reliability, we identified pediatric liver transplant centers in North America with lowest hepatic artery thrombosis rate biliary complication rates. A survey was completed...
We assessed 41 children and adolescents who had received liver transplants at least 4 years ago, for social, behavioral, emotional adaptation; physical function; family stress. compared their level of adaptive functioning to published data from chronically ill medically well children. On many measures, transplant recipients equivalent levels function the comparison groups. However, 6- 11-year-old patients showed mild social scholastic deficits. Patients' parents report less negative impact...
The goal of this work was to examine the change in health‐related quality life (HRQOL) and cognitive functioning from early childhood adolescence pediatric liver transplantation (LT) recipients. Patients were recruited 8 North American centers through Studies Pediatric Liver Transplantation consortium. A total 79 participants, ages 11‐18 years, previously tested at age 5‐6 years Functional Outcomes Group study identified as surviving most recent LT by 2 stable medical follow‐up. Quality Life...
Fifty long-term (3-9 year) survivors of pediatric liver transplantation were assessed using IQ, achievement, and school history measures. Forty-seven these children had been evaluated before on intellectual measures, with mean scores for the group found to be in low average range. At follow-up evaluation, remained range all measures; performance academic tests was also within Thirteen (26%) classified as having learning problems based discrepancies between function, but only five them (38%)...
Purpose Gardner syndrome, a variant of familial adenomatous polyposis, is characterized by colonic polyps that undergo malignant change and benign extracolonic lesions. Tumors frequently associated with syndrome include carcinoma the ampulla Vater, papillary thyroid, and, in children, hepatoblastoma. The childhood malignancies often precede appearance other manifestations several years. Patients Methods Two patients are described. was diagnosed 15-year-old girl fibrolamellar hepatocellular...
The most common hepatic complications of cystic fibrosis (CF) are steatosis, fibrosis, biliary cirrhosis, atretic gallbladder, cholelithiasis, and sclerosing cholangitis. Cholestatic liver disease is a slow progressive disorder, but will stabilize for many patients. CF patients may suffer from the consequences their without transplantation, variceal hemorrhage, malnutrition, or end-stage can lead to death. Prospective data were collected reviewed on 311 transplants performed in 283 at...
Although children with end-stage liver disease (ESLD) have been found to cognitive delays, the relationship between patterns of function and diagnostic category, age onset, duration severity has not assessed before transplantation. Verbal performance IQ (VIQ, PIQ) scores on Bannatyne's factors for 43 ESLD were compared those 15 control cystic fibrosis (CF) existing normative data. Children biliary atresia had deficits in PIQ, spatial sequential scores. alpha-1 antitrypsin deficiency did...
Dystonia is a common, debilitating, and often treatment-refractory motor symptom of cerebral palsy (CP), affecting 70%-80% this population based on research assessments. However, routine clinical evaluation for dystonia in CP has failed to match these expected numbers. Addressing diagnostic gap medical imperative because the presence rules or out certain treatments symptoms CP. Therefore, our objective was optimize rates screening improve diagnosis. Using quality improvement (QI)...