Manoj K. Singh

ORCID: 0000-0003-0197-6876
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About
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Research Areas
  • Plant Reproductive Biology
  • Cellular transport and secretion
  • Plant Molecular Biology Research

University of Tübingen
2020

Membrane trafficking maintains the organization of eukaryotic cell and delivers cargo proteins to their subcellular destinations, such as sites action or degradation. The formation membrane vesicles requires activation ADP-ribosylation factor ARF GTPase by SEC7 domain guanine-nucleotide exchange factors (ARF-GEFs), resulting in recruitment coat GTP-bound ARFs. In vitro assays were done with monomeric proteins, although ARF-GEFs form dimers vivo. This feature is conserved across eukaryotes,...

10.1105/tpc.20.00240 article EN The Plant Cell 2020-06-02
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