A5078802095- Air Quality and Health Impacts
- Noise Effects and Management
- Climate Change and Health Impacts
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Asthma and respiratory diseases
- Urban Green Space and Health
- Allergic Rhinitis and Sensitization
- Indoor Air Quality and Microbial Exposure
- Physical Activity and Health
- Obesity, Physical Activity, Diet
- Urban Heat Island Mitigation
- Energy and Environment Impacts
- Dermatology and Skin Diseases
- Air Quality Monitoring and Forecasting
- Health, Environment, Cognitive Aging
- Antibiotic Use and Resistance
- Neonatal Respiratory Health Research
- Global Health Care Issues
- Birth, Development, and Health
- Respiratory and Cough-Related Research
- Health disparities and outcomes
- Land Use and Ecosystem Services
- Pediatric health and respiratory diseases
- Respiratory Support and Mechanisms
- Nutritional Studies and Diet
Imperial College London
2018-2025
MRC Centre for Environment and Health
2022-2025
Barcelona Institute for Global Health
2016-2020
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2016-2020
Universitat Pompeu Fabra
2016-2020
Lung Institute
2019-2020
Royal Brompton Hospital
2020
Finnish Institute of Occupational Health
2020
Helmholtz Zentrum München
2013-2018
Center for Research in Environmental Epidemiology
2016-2018
Few studies have investigated traffic-related air pollution as a risk factor for respiratory infections during early childhood.We aimed to investigate the association between and pneumonia, croup, otitis media in 10 European birth cohorts--BAMSE (Sweden), GASPII (Italy), GINIplus LISAplus (Germany), MAAS (United Kingdom), PIAMA (the Netherlands), four INMA cohorts (Spain)--and derive combined effect estimates using meta-analysis.Parent report of physician-diagnosed media, croup childhood...
Epidemiological studies have identified associations between air pollution and green space access with type 2 diabetes in adults. However, it remains unclear to what extent greenness are attributable exposure.We aimed investigate long-term exposure satellite-derived insulin resistance adolescents.A total of 837 participants two German birth cohorts (LISAplus GINIplus) were included the analysis. Generalized additive models used determine association individual defined by Normalized...
The aim of this study was to determine the effect six traffic-related air pollution metrics (nitrogen dioxide, nitrogen oxides, particulate matter with an aerodynamic diameter <10 μm (PM 10 ), PM 2.5 , coarse and absorbance) on childhood asthma wheeze prevalence in five European birth cohorts: MAAS (England, UK), BAMSE (Sweden), PIAMA (the Netherlands), GINI LISA (both Germany, divided into north south areas). Land-use regression models were developed for each area used estimate outdoor...
According to Ulrich's psychoevolutionary theory, contact with green environments mitigates stress by activating the parasympathetic system, (specifically, decreasing blood pressure (BP)). Experimental studies have confirmed this biological effect. However, greenness effects on BP not yet been explored using an observational study design. We assessed whether surrounding residential is associated in 10 year-old German children. Systolic and diastolic BPs were children residing Munich Wesel...
The prevalence of allergic rhinitis is high, but the role environmental factors remains unclear. We examined cohort-specific and combined associations residential greenness with aeroallergen sensitization based on individual data from Swedish (BAMSE), Australian (MACS), Dutch (PIAMA), Canadian (CAPPS SAGE), German (GINIplus LISAplus) birth cohorts (n = 13 016).Allergic (doctor diagnosis/symptoms) were assessed in children aged 6-8 years six 10-12 five cohorts. Residential was defined as mean...
We assessed the effect of three different indices urban built environment on allergic and respiratory conditions.This study involved 2472 children participating in ongoing INMA birth cohort located two bio-geographic regions (Euro-Siberian Mediterranean) Spain. Residential surrounding was characterised as 1) residential greenness based satellite-derived normalised difference vegetation index (NDVI), 2) proximity to green spaces 3) greyness land use patterns. Information wheezing, bronchitis,...
The evidence supporting an association between traffic-related air pollution exposure and incident childhood asthma is inconsistent may depend on genetic factors.To identify gene-environment interaction effects using genome-wide single-nucleotide polymorphism (SNP) data exposure. Identified loci were further analyzed at epigenetic transcriptomic levels.We used land use regression models to estimate individual (represented by outdoor NO2 levels) the birth address performed a study for...
Background Positive greenness effects on health are increasingly reported, although studies allergic outcomes remain limited and conflicting. We examined whether residential is associated with childhood doctor diagnosed rhinitis, eyes nose symptoms aeroallergen sensitisation using two combined birth cohorts (GINIplus LISAplus) followed from to 10 years in northern southern Germany (N total =5803). Methods Mean a 500 m buffer around the 10-year home addresses was defined Normalized Difference...
We assessed associations between physical activity and lung function, its decline, in the prospective population-based European Community Respiratory Health Survey cohort.FEV1 FVC were measured 3912 participants at 27-57 years 39-67 (mean time examinations=11.1 years). Physical frequency duration using questionnaires used to identify active individuals (physical ≥2 times ≥1 hour per week) each examination. Adjusted mixed linear regression models of regular with FEV1 FVC.Physical increased...
Genetics may partially explain observed heterogeneity in associations between traffic-related air pollution and incident asthma.Our aim was to investigate the impact of gene variants associated with oxidative stress inflammation on childhood asthma.Traffic-related pollution, asthma, wheeze, variant, potential confounder data were pooled across six birth cohorts. Parents reported physician-diagnosed asthma wheeze from 7-8 years age (confirmed by pediatric allergist two cohorts). Individual...
Background. There is a need to study whether the adverse effects of traffic-related air pollution (TRAP) on childhood asthma and allergic diseases documented during early-life persist into later childhood. This longitudinal examined TRAP associated with prevalence asthma, rhinitis aeroallergen sensitization in two German cohorts followed from birth 10 years. Materials. Questionnaire-derived annual reports doctor diagnosed rhinitis, as well eye nose symptoms, were collected 6,604 children....