A5002515669- Antibiotic Resistance in Bacteria
- Probiotics and Fermented Foods
- Antibiotics Pharmacokinetics and Efficacy
- Enterobacteriaceae and Cronobacter Research
- Bacterial biofilms and quorum sensing
- Antibiotic Use and Resistance
- Pharmaceutical and Antibiotic Environmental Impacts
- Bacterial Identification and Susceptibility Testing
- Urinary Tract Infections Management
- Food Quality and Safety Studies
- Vibrio bacteria research studies
- Escherichia coli research studies
- Gut microbiota and health
- Pharmacological Effects of Natural Compounds
- Infections and bacterial resistance
- Mycobacterium research and diagnosis
- Hemostasis and retained surgical items
- Medical Research and Treatments
- Transgenic Plants and Applications
- Biochemical effects in animals
- Traditional Chinese Medicine Studies
- Animal health and immunology
- Phytoestrogen effects and research
- Microbial Metabolism and Applications
- Microbial Metabolites in Food Biotechnology
Samsung Medical Center
2018
Sungkyunkwan University
2018
Fundación para el Desarrollo Integral del Pacífico
2013-2018
Sahmyook University
2010-2014
Abstract Background Recent studies have reported the preventive effects of probiotics on obesity. Among commensal bacteria, bifidobacteria is one most numerous in mammalian gut and are a type lactic acid bacteria. The aim this study was to assess antiobesity lipid-lowering Bifidobacterium spp. isolated from healthy Korean high fat diet-induced obese rats. Methods Thirty-six male Sprague-Dawley rats were divided into three groups as follows: (1) SD group, fed standard diet; (2) HFD (3)...
Although extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) has emerged as a significant community-acquired pathogen, there is little epidemiological information regarding community-onset bacteremia due to ESBL-EC. A retrospective observational study from 2006 through 2011 was performed evaluate the epidemiology of caused by In six-year period, proportion ESBL-EC responsible for causing had increased significantly, 3.6% in 14.3%, 2011. Of 97 clinically evaluable cases with...
Despite the remarkable emergence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli sequence type 131 (ST131), clinical features and outcomes infections caused by ST131 remain poorly described. From 2011 to 2012, we collected ESBL-producing E. isolates from patients with bloodstream in 13 hospitals Korea compared characteristics between non-ST131 clones. Of 110 isolates, most common ST was (30.9%). Multivariate analysis showed that recent operation only variable associated...
We evaluated the in vitro activity of various antimicrobials alone and combination against 291 extended-spectrum-β-lactamase-producing Escherichia coli (ESBL-EC) isolates causing bacteremia South Korean hospitals. Ceftazidime, cefepime, piperacillin-tazobactam with amikacin showed greater than found ciprofloxacin. In settings a high prevalence ESBL-producing pathogens, aminoglycoside antimicrobial therapy, especially amikacin, may be considered for empirical therapy suspected Gram-negative...
During recent decades, the rates of multidrug resistance, including resistance to carbapenems, have increased dramatically among Acinetobacter species. Tigecycline has activity against multidrug-resistant spp, carbapenem-resistant isolates. However, reports tigecycline-resistant spp are emerging from different parts world. The purpose this study was evaluate potential risk factors associated with tigecycline non-susceptible bacteremia.The medical records 152 patients bacteremia attending...
We investigated the antimicrobial susceptibility, genotypic distributions of extended-spectrum β-lactamase (ESBL) and AmpC genes, molecular epidemiology AmpC-producing Klebsiella pneumoniae (AmpC-KP) isolates causing bacteremia. Among 260 K. clinical included in this study, plasmid-mediated β-lactamases were found 20.7% (54/260), which DHA-1 (96.3%, 52/54), CMY-2 (3.7%, 2/54), CMY-10 (1.9%, 1/54). One isolate also produced along with CMY-2. Of 54 AmpC-KP isolates, 31 (57.4%) showed ESBL...
In the present study Lactobacillus plantarum CBT1209, Pediococcus pentosaceus CBT SL4, and Bifidobacterium longum SPM1205 showed curd formation in soy milk for 8 hours of incubation time a single-culture experiment. Among these strains, B. as new isolated strain, inhibited activity fecal harmful enzymes rat. Therefore, we investigated possibility using mixed culture containing SPM1205for obtaining curd-type soy-based yogurt with respect to formation, proximate composition sensory attributes....
Probiotics do not naturally have a high stability and shelf life because they are living microorganisms. In an effort to maximise their survival, we developed new dual coating LAB, trademarked as Duolac. This study aims compare the probiotic effects of coated LAB uncoated through in vivo vitro testing. Groups SD rats were orally administered saline (as control group), Duolac or meal 1x109 CFU per day for four weeks. We collected fecal samples investigate inhibition harmful enzyme activity....
While carbapenems are the drug of choice to treat extended-spectrum-β-lactamase (ESBL)-producing strains, some alternative carbapenem-sparing regimens suggested for antibiotic stewardship. We experienced a case ciprofloxacin treatment failure acute pyelonephritis caused by an apparently susceptible Escherichia coli. A 71-year-old woman presented emergency department with fever 7 days and bilateral flank pain 2 days. The laboratory results abdominopelvic computed tomography finding were...
We investigated the molecular epidemiology and microbiological characteristics of 51 Escherichia coli isolates causing hospital-acquired pneumonia (HAP) in eight Asian areas. Sequence type 131 (ST131) was most prevalent among E. HAP, especially South Korea, Thailand, Philippines. The current study showed that CTX-M-15-producing ST131 has emerged disseminated patients with HAP Asia. Our data suggest this pandemic clone poses an important public health threat even nosocomial infections.
ABSTRACTDiarrhea-producing enteropathogenic bacteria infections in calves continue to be a major world-wide problem. In particular, neonatal calf diarrhea remains an important cause of morbidity and mortality young calves. Traditionally, formulated antibiotics have been used as preventive treatment. However, consumer concern about antibiotic resistance has increased interest alternative supplements grown. The aim this study was test the efficacy Lactic acid (LAB) supplement, which includes...
The purpose of this study was to assess the microbiological quality unchlorinated drinking water in Korea, 2010. One hundred and eighty samples were collected from various sites Seoul Gyeonggi province.To investigate bacterial presence, pour plate method used with cultures grown on selective media for total bacteria, coliforms, Staphylococcus spp., respectively.In 180 bacteria investigation, 72 33 province an unacceptable (>10(2) CFU/mL). Of all tested, coliforms detected 28 (15.6%) spp. 12...
녹농균은 특히 면역이 저하된 환자에게서 심각한 감염을 일으키는 그람음성의 기회감염 균주이다. 또한 carbapenem 내성 metallo-<TEX>${\beta}$</TEX>-lactamases (MBL)를 가진 녹농균이 한국에서 증가되는 추세로 보고되고 있다. 따라서 본 실험에서는 2차 병원인 삼육 서울 병원에서 수집된 총 92종의 임상 녹농균의 다재내성 수준을 분석하였다. 항생제에 대한 감수성은 최소억제농도(MIC) 분석에 의해 결정되었고, inhibitor-potentiated disk diffusion(IPD) 분석은 MBL 검출을 위해 수행되었다. RAPD-PCR은 임상환자에서 분리한 녹농균 계통의 유전적 유형의 특징을 밝히기 사용되었다. 그 결과 임상에서 분리된 40.2%는 ceftazidime에 내성을, 58.7%는 meropenem에 56.5%는 gentamicin에 46.7%는 tobramycin에 62.0%는 ciprofloxacin에 내성을 그리고...