A5036212822- Neurobiology and Insect Physiology Research
- Invertebrate Immune Response Mechanisms
- Insect symbiosis and bacterial influences
- Cognitive Science and Mapping
- Gene expression and cancer classification
- Animal Behavior and Reproduction
- Physiological and biochemical adaptations
- Developmental Biology and Gene Regulation
- Sleep and Wakefulness Research
- Insect and Arachnid Ecology and Behavior
- Genetic Mapping and Diversity in Plants and Animals
- Insect Utilization and Effects
- Multi-Criteria Decision Making
- Morphological variations and asymmetry
- Cognitive Abilities and Testing
- Genetics and Physical Performance
- Child and Animal Learning Development
- Technology Assessment and Management
- Biomedical Text Mining and Ontologies
- Entomopathogenic Microorganisms in Pest Control
- Mollusks and Parasites Studies
- Genetic Syndromes and Imprinting
- Memory and Neural Mechanisms
- Helminth infection and control
- Memory Processes and Influences
University of Göttingen
2019-2025
Max Planck Institute for Human Development
2022-2023
Abstract Background The compound eyes of insects exhibit extensive variation in ommatidia number and size, which affects how they see underlies adaptations their vision to different environments lifestyles. However, very little is known about the genetic developmental bases differences eye size. We previously showed that larger Drosophila mauritiana compared D. simulans are generally caused by size rather than number. Furthermore, we identified an X-linked chromosomal region results when...
Exocrine glands have evolved several times independently in Coleoptera to produce defensive chemical compounds with repellent, antimicrobial, or toxic effects. Research on such had focused morphological ecology methods. However, modern genetic approaches were missing better understand this biological process. With the rise of red flour beetle, Tribolium castaneum, as a model for studies development and pest biology, molecular tools are now available also study safe generation stink glands....
Revealing the mechanisms underlying breathtaking morphological diversity observed in nature is a major challenge Biology. It has been established that recurrent mutations hotspot genes cause repeated evolution of traits, such as body pigmentation or gain and loss structures. To date, however, it remains elusive whether contribute to natural variation size shape organs. As head morphology pervasive Drosophila, we studied molecular developmental basis differences compound eye two closely...
Abstract Background Pleuropodia are limb-derived glandular organs that transiently appear on the first abdominal segment in embryos of insects from majority “orders”. They missing genetic model Drosophila and little is known about them. Experiments carried out orthopteran 80 years ago indicated pleuropodia secrete a “hatching enzyme” digests serosal cuticle to enable larva hatch, but evidence by state-of-the-art molecular methods missing. Results We used high-throughput RNA-sequencing...
Memories enable the retrieval of specific events in past while building generalizable knowledge that guides inference new situations. According to a prominent conceptualization, serving both these adaptive functions requires pattern separation, completion, and generalization as distinct sets complementary component processes. It is not known whether three processes are separable early childhood or they originally represent single dimension memorability differentiates middle childhood. Based...
Abstract The compound eyes of insects exhibit extensive variation in ommatidia number and size, which affects how they see underlies adaptations their vision to different environments lifestyles. However, very little is known about the genetic developmental bases differences eye size. We previously showed that larger Drosophila mauritiana compared D. simulans generally caused by size rather than number. Furthermore, we identified an X-linked chromosomal region results when introgressed into...
Research in various fields of evolutionary biology has shown that divergence gene expression is a key driver for phenotypic variation. An exceptional contribution cis-regulatory evolution instance been found to contribute morphological diversification. In the light these findings, analysis genome-wide data become one central tools link genotype and phenotype information on more mechanistic level. However, many studies, especially if general conclusions are drawn from such data, feature...
Adaptive memories are formed in the face of a fundamental tension: extracting commonalities across experiences to generate novel inferences (i.e., generalization), while simultaneously forming separate representations similar events memory specificity). Theoretical models suggest that specific initially encoded as hippocampus-dependent episodic and slowly become amenable generalization through consolidation. Post-learning sleep facilitates such consolidation processes. However, can also...
ABSTRACT Pleuropodia are limb-derived vesicular organs that transiently appear on the first abdominal segment of embryos from majority insect “orders”. They missing in model Drosophila and little is known about them. Experiments carried out orthopteran insects eighty years ago indicated pleuropodia secrete a “hatching enzyme” at end embryogenesis digests serosal cuticle to enable larva hatch. This hypothesis contradicts view digested by enzymes produced tissue deposited it. We studied...
Abstract Revealing the mechanisms underlying breath-taking morphological diversity observed in nature is a major challenge Biology. It has been established that recurrent mutations hotspot genes cause repeated evolution of rather simple traits, such as body pigmentation or gain and loss structures. To date, however, it remains elusive whether contribute to natural variation complex size shape organs. Since head morphology pervasive Drosophila , we studied molecular developmental basis...
Pleuropodia are limb-derived glandular organs that transiently appear on the first abdominal segment in embryos of insects from majority “orders”. They missing genetic model Drosophila and little is known about them. Experiments carried out orthopteran 80 years ago indicated pleuropodia secrete a “hatching enzyme” digests serosal cuticle to enable larva hatch, but evidence by state-of-the-art molecular methods missing. We used high-throughput RNA-sequencing identify genes expressed locust...
Cumulative science hinges on consolidating empirical evidence. However, both narrative reviews and meta-analyses often restrict integration by using construct labels in searches, which vary greatly across traditions eras psychology. An alternative is the mapping review, more common other disciplines, focuses operational definitions experimental design. Here, we pioneered this approach psychology, applying it to memory development. We classified 506 publications last 5 decades 16 design...
Determining the compositional structure and dimensionality of psychological constructs lies at heart many research questions in developmental science. Structural equation modelling (SEM) provides a versatile framework for formalizing estimating relationships among multiple latent constructs. While flexibility SEM can accommodate complex assumptions on underlying constructs, it makes a-priori estimation statistical power required sample size challenging. This difficulty is magnified when...
Childhood cognitive control is an important predictor for positive development, yet interventions seeking to improve it have provided mixed results. This partly due lack of clarity surrounding mechanisms control, notably the role inhibition and context monitoring. Here we use a randomized controlled trial causally test contributions monitoring in childhood. Sixty children aged 6 9-years were assigned three groups training either inhibition, group or response speed using gamified, highly...