A5049752005- Force Microscopy Techniques and Applications
- Rheology and Fluid Dynamics Studies
- Mechanical and Optical Resonators
- Lipid Membrane Structure and Behavior
- Block Copolymer Self-Assembly
- Supramolecular Chemistry and Complexes
- Advanced Polymer Synthesis and Characterization
- Cellular Mechanics and Interactions
University of Manchester
2024-2025
Institute of Theoretical Physics
2006
Jilin University
2006
Force-controlled release of small molecules offers great promise for the delivery drugs and healing or reporting agents in a medical materials context
Mechanophores (mechanosensitive molecules) are usually activated by pulling them with covalently attached polymers. A rotaxane actuator offers a new geometry of activation as the macrocycle pushes against stoppering mechanophore. Here we compare both and pushing activations show that is more efficient selective than pulling. We found bulky furan/maleimide adduct occurs via two competing dissociation pathways: retrocycloaddition heterolytic cleavage (generating trityl cation in process),...
Bowser et al. have shown that substituents stabilising the diradical character of symmetry-forbidden disrotatory pathway accelerate mechanochemical ring-opening cis -cyclobutenes ( Chem Sci. , 2025, https://doi.org/10.1039/D5SC00253B).
The microphase separation of miktoarm block copolymers with different compositions and chain rigidities is studied using dissipative particle dynamics in two dimensions. pure coil, rod-coil, pure-rod models are considered, complex micelles, tubular lamellae networks morphologies obtained for these systems. influence the molecule flexibility shape on morphology emphasized special "Y"- "T"-shaped copolymers. From an application point view, results will be helpful designing new templates thin...