- Polysaccharides and Plant Cell Walls
- Fungal Biology and Applications
- Seaweed-derived Bioactive Compounds
- Luminescence Properties of Advanced Materials
- Microbial Metabolites in Food Biotechnology
- Polysaccharides Composition and Applications
- Analytical chemistry methods development
- Ginger and Zingiberaceae research
- Glass properties and applications
- Solid State Laser Technologies
- Protein Hydrolysis and Bioactive Peptides
- Seed and Plant Biochemistry
- Mycotoxins in Agriculture and Food
- Heavy metals in environment
- Arsenic contamination and mitigation
- Phytochemicals and Antioxidant Activities
- Free Radicals and Antioxidants
- Selenium in Biological Systems
- Laser-induced spectroscopy and plasma
- Natural product bioactivities and synthesis
- Phytochemical compounds biological activities
- Proteins in Food Systems
- Enzyme Production and Characterization
- Food composition and properties
- Heavy Metals in Plants
China Pharmaceutical University
2016-2025
State Council of the People's Republic of China
2020
Nanjing Library
2020
Rutgers, The State University of New Jersey
2015
Chinese Academy of Sciences
2008-2011
Fujian Institute of Research on the Structure of Matter
2008-2011
Jilin University
2010
University of Chinese Academy of Sciences
2008
Zhengzhou University of Light Industry
2008
Chinese PLA General Hospital
2006
Quinoa is a nutrient-rich pseudocereal with lower glycemic index and load. However, its therapeutic potency underlying mechanism against insulin resistance (IR) have not been fully elucidated. In this work, network pharmacology was applied to screen IR targets their related pathways. The efficacy of black quinoa polyphenols (BQP) on improvement were evaluated uncovered based the model in vitro combined molecular docking. Ten phenolic constituents BQP detected, results show that PI3K/Akt...
Using the <italic>Flammulina velutipes</italic> polysaccharide (FVP) extracted from our previous study, herein, we investigated improvement of this β-type glycosidic in alleviating dextran sodium sulfate-induced ulcerative colitis (UC) mice.
In previous study, we got a purified ginger polysaccharide UGP1 and verified its significant antitumor activities on colon cancer HCT116 cells. this article, aimed to illustrate the underlying mechanism of exerted by using in vitro cell models vivo animal models. The results demonstrated that could induce S-phase cycle arrest, up-regulate expression Bax p53, down-regulate Bcl-2, activate downstream protein caspase-9 caspase-3, which was related intrinsic apoptosis pathway Moreover,...
Abstract Microwave-assisted extraction (MAE) was applied for the of astaxanthin from Haematococcus pluvialis and response surface methodology (RSM) used to optimize parameters content astaxanthin. Four independent variables such as microwave power (W), time (sec), solvent volume (mL), number were optimized in this paper. The optimal conditions determined tri-dimensional surfaces plotted mathematical models. F-test p-value indicated that power, time, extraction, their quadratic had a highly...
Four drying methods, viz hot air (HD), vacuum (VD), microwave-vacuum (MVD), and freeze-drying (FD), were used to dry white Hypsizygus marmoreus (WHM). The volatile taste components of the dried WHM comparatively analysed by electronic nose technology (E-nose) head-space solid-phase microextraction combined with gas chromatography-mass spectrometry (HS-SPME-GS-MS). Principal component analysis (PCA) showed that E-nose could distinguish fresh four products clearly. Dominant in found be...
Iron deficiency anemia (IDA) is a common nutritional problem, but traditional iron supplements cause many adverse reactions. Thus, the development of novel supplement might be significant for treatment IDA. This study aimed to transport mechanism Flammulina velutipes polysaccharide-iron complex (FVP1-Fe(III)) in Caco-2 cells and therapeutic effect on IDA rats, as well influence gut microbiota vivo. These results showed that vitro, uptake FVP1-Fe(III) was mediated by sodium-dependent glucose...
Abstract Peanut protein was hydrolysed with a commercial protease, Alcalase 2.4L, and the resulting hydrolysate investigated for its antioxidant activities, including ability to inhibit autoxidation of linoleic acid, scavenging effect on 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) free radical, reducing power inhibition liver lipid oxidation. As compared peanut protein, showed strong scavenge DPPH radical power. Moreover, also displayed noticeable oxidation induced by H 2 O or Fe 2+ in vitro . All...
Abstract The objective of this study was to create a healthier version commonly consumed baked food (cookies) by replacing some the wheat flour with nutraceutical‐rich mushroom flour. impact incorporating different levels powdered ( Pleurotus eryngii ) on rheological properties cookie dough and final cookies therefore determined. supplemented 0%–25% w / were analyzed using Mixolab instrument shear rheometer. Increasing ratio mushroom‐to‐wheat in doughs increased peak viscosities, but...
This study evaluated the effect of triterpenoids from edible mushroom Poria cocos on intestinal epithelium integrity and revealed transcriptional regulatory pathways that underpin restorative mechanisms in gut. Based computational docking studies, activation experiments glucocorticoid receptor (GR) protein immunofluorescence localization assays cultured cells, 16α-hydroxytrametenolic acid (HTA) was discovered as a novel GR agonist this study. HTA ameliorates TNF-α-induced Caco-2 monolayer...