A5100693764- Cancer, Stress, Anesthesia, and Immune Response
- Cancer Cells and Metastasis
- Brain Metastases and Treatment
- MicroRNA in disease regulation
- Breast Cancer Treatment Studies
- Cancer Genomics and Diagnostics
- Alzheimer's disease research and treatments
- Axon Guidance and Neuronal Signaling
- Extracellular vesicles in disease
Shanxi Academy of Medical Sciences
2020-2022
Fujian Medical University
2022
Shanxi Medical University
2022
Abstract Active crosstalk between the nervous system and breast cancer cells has been experimentally demonstrated in vitro animal models. However, low frequencies of peripheral nerve presence human cancers reported previous studies (~30% cases) potentially negate a major role development progression. This study aimed to clarify incidence nerves within delineate associations with clinicopathological features. Immunohistochemical staining was conducted formalin‐fixed paraffin‐embedded tissue...
Dysregulation of microRNAs has been implicated in diverse diseases, including Alzheimer's disease (AD). MiR-191-5p plasma/serum identified as a novel and promising noninvasive diagnostic biomarker for AD. However, whether miR-191-5p is involved AD pathogenesis largely unknown, its levels human brains are undetermined. Herein, we demonstrated that downregulated tau phosphorylation at multiple AD-related sites promoted neurite outgrowth using immunoblotting, immunofluorescence, assays....
Pathological complete response (pCR) to neoadjuvant chemotherapy (NACT) is associated with favourable outcomes of patients triple-negative breast cancer (TNBC). However, a proportion TNBC the residual disease do not relapse and achieve long-term survival. The aim this study was identify biomarkers that predict clinical in these patients.
Abstract Background: Active crosstalk between the nervous system and breast cancer cells as well other cell types within tumour microenvironment has been experimentally demonstrated in vitro animal models. However, low frequencies of peripheral nerve presence human cancers reported previous studies (~30% cases) potentially negate a major role development progression. This study aimed to better define incidence nerves delineate associations with clinicopathological features. Methods :...