A5100616013- Berberine and alkaloids research
- Regulation of Appetite and Obesity
- Adipokines, Inflammation, and Metabolic Diseases
- Natural Antidiabetic Agents Studies
- Cholesterol and Lipid Metabolism
- Adipose Tissue and Metabolism
- Diet, Metabolism, and Disease
- Advanced Photocatalysis Techniques
- Pancreatic function and diabetes
- Antioxidant Activity and Oxidative Stress
- Alzheimer's disease research and treatments
- Biochemical effects in animals
- Fatty Acid Research and Health
- Phytochemicals and Antioxidant Activities
- Algal biology and biofuel production
- Phytoestrogen effects and research
- Ginseng Biological Effects and Applications
- Smoking Behavior and Cessation
- Metabolism, Diabetes, and Cancer
- Drug Transport and Resistance Mechanisms
- Copper-based nanomaterials and applications
- Aquaculture Nutrition and Growth
- Chromatography in Natural Products
- Voice and Speech Disorders
- Peroxisome Proliferator-Activated Receptors
State Ethnic Affairs Commission
2024
Shanghai Jiao Tong University
2024
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2019-2023
Shanghai University of Traditional Chinese Medicine
2019-2023
National Research Council Canada
2012-2022
Zhejiang University
2020-2022
West China Medical Center of Sichuan University
2020-2022
Zhejiang Hospital
2015-2022
Peking University
2022
Chinese Center For Disease Control and Prevention
2022
Genistein, a flavonoid in legumes and some herbal medicines, has various biological actions. However, studies on whether genistein an effect pancreatic β-cell function are very limited. In the present study, we investigated of proliferation cellular signaling related to this further determined its antidiabetic potential insulin-deficient diabetic mice. Genistein induced both INS1 human islet after 24 h incubation, with 5 μm inducing maximal 27% increase. The was neither dependent estrogen...
Ursolic acid (UA) is a triterpenoid compound with multiple biological functions. This has recently been reported to possess an anti-obesity effect; however, the mechanisms are less understood.As adipogenesis plays critical role in obesity, present study was conducted investigate effect of UA on and action 3T3-L1 preadipocytes.The preadipocytes were induced differentiate presence or absence for 6 days. The cells determined proliferation, differentiation, fat accumulation as well protein...
Background Nuciferine is a major active aporphine alkaloid from the leaves of N. nucifera Gaertn that possesses anti-hyperlipidemia, anti-hypotensive, anti-arrhythmic, and insulin secretagogue activities. However, it currently unknown whether nuciferine can benefit hepatic lipid metabolism. Methodology/Principal Findings In current study, male golden hamsters were randomly divided into four groups fed normal diet, high-fat diet (HFD), or HFD supplemented with (10 15 mg/kg·BW/day). After 8...
Liuwei Dihuang (LWDH), a classic Chinese medicinal formula, has been used to improve or restore declined functions related aging and geriatric diseases, such as impaired mobility, vision, hearing, cognition memory. Here, we report on the effect possible mechanisms of LWDH mediated protection β-amyloid (Aβ) induced paralysis in Caenorhabditis elegans using ethanol extract (LWDH-EE) water (LWDH-WE). Chemical profiling quantitative analysis revealed presence different levels bioactive...
The present study was conducted to evaluate the protein quality of microalgae species Chlorella vulgaris (CV), sorokiniana (CS), and Acutodesmus obliquus (AO) assess impact mechanical cell wall disruption. Male Sprague-Dawley rats, around 156 g after adaptation, were placed in metabolic cages fed experimental diets that either protein-free or contained 10% solely from one undisrupted disrupted CV, CS, AO. After 3 days, feces collected for a period 5 days analyzed together with diet samples...
Antimony sulfide (Sb2S3) is a one-dimensional semiconductor stacking (Sb4S6)n ribbons with van der Waals force, which shows anisotropic features along different orientations. Controlling the grain orientation an efficient strategy to enhance PEC performance of Sb2S3 photocathodes. Here, we successfully fabricated photocathode employing as absorber material [hk1] orientation, suitable for sufficiently harvesting sunlight and solar energy conversion. After sequentially depositing n-type CdS...
The present study was carried out to determine the effect of berberine on glucose homeostasis and several biomarkers associated with insulin sensitivity in male Wistar rats intraperitoneal injection streptozotocin (STZ)-induced diabetes. Rats fasting blood 16.7 mmol/L after 2 weeks STZ were divided into two groups. One group used as diabetic control another treated by gavage feeding 100 mg/kg/d water containing 0.5% carboxymethyl cellulose. A without receiving normal control. After 7 weeks,...
Background. The endogenous cholesterol fractional synthesis rate (FSR) is related inversely to infant dietary at 4 months of age; however, it remains be established whether this effect permanent, possibly contributing later hypercholesterolemia. Objective. To determine levels in infancy induced changes FSR and plasma lipid that persisted 18 months. Methods. A prospective clinical trial was conducted with 47 infants, from their first week life until age, who received human milk (HM) weaned (n...
A polyol-mediated synthetic method has been developed to prepare ultrafine anatase TiO2 nanocrystals of about 2−5 nm in size, which, when connected, form a network with porous structure. The physiochemical properties these are tuned by doping Ni. High-resolution X-ray photoelectron spectroscopy analysis revealed that Ni incorporates into the framework Ti−O−Ni chain. Nitrogen adsorption measurements further showed can greatly enhance surface area from 143 266 m2/g. Using UV−vis diffuse...