Stephen Hwang
A5062078487- Genomics and Phylogenetic Studies
- Genomics and Chromatin Dynamics
- Mathematics Education and Teaching Techniques
- Data Management and Algorithms
- Chromosomal and Genetic Variations
- Semantic Web and Ontologies
- Education Pedagogy and Practices
- Epigenetics and DNA Methylation
- Education and Critical Thinking Development
- Gene expression and cancer classification
- Genetic diversity and population structure
- Identification and Quantification in Food
- Web Data Mining and Analysis
- Cognitive and developmental aspects of mathematical skills
Johns Hopkins University
2022-2025
The human Y chromosome has been notoriously difficult to sequence and assemble because of its complex repeat structure including long palindromes, tandem repeats, segmental duplications 1–3 . As a result, more than half the is missing from GRCh38 reference it remains last be finished 4, 5 Here, Telomere-to-Telomere (T2T) consortium presents complete 62,460,029 base pair HG002 genome (T2T-Y) that corrects multiple errors in GRCh38-Y adds over 30 million pairs reference, revealing ampliconic...
Advances in long-read sequencing technology has led to a rapid increase high-quality genome assemblies. These make it possible compare sequences across the Tree of Life, deepening our understanding evolutionary relationships. Average nucleotide identity (ANI) is distance measure that been applied species delineation, building guide trees, and searching large sequence databases. Since computing ANI computationally expensive, field increasingly turned sketch-based approaches use assumptions...
Abstract Pangenomes are growing in number and size, thanks to the prevalence of high-quality long-read assemblies. However, current methods for studying sequence composition conservation within pangenomes have limitations. Methods based on graph require a computationally expensive multiple-alignment step, which can leave out some variation. Indexes k -mers de Bruijn graphs limited answering questions at specific substring length . We present Maximal Exact Match Ordered (MEMO), pangenome...
Abstract Research has shown that teaching mathematics through problem posing, or problem-posing based learning (P-PBL), is a student-centered instructional approach can improve students’ cognitive and affective aspects of learning. However, since textbooks continue to include very few opportunities for researchers have been working support teachers integrate posing into classroom instruction, drawing on as resource. In this paper, we describe how in the P-PBL Project engaged change with from...
Pangenomes are growing in number and size, thanks to the prevalence of high-quality long-read assemblies. However, current methods for studying sequence composition conservation within pangenomes have limitations. Methods based on graph require a computationally expensive multiple-alignment step, which can leave out some variation. Indexes
<title>Abstract</title> Pangenomes are growing in number and size, thanks to the prevalence of high-quality long-read assemblies. However, current methods for studying sequence composition conservation within pangenomes have limitations. Methods based on graph require a computationally expensive multiple-alignment step, which can leave out some variation. Indexes k-mers de Bruijn graphs limited answering questions at specific substring length k. We present Maximal Exact Match Ordered (MEMO),...
Em 1994, Ed Silver publicou um artigo original intitulado “On Mathematical Problem Posing”. tanto ajudou a estabelecer as bases para pesquisa de proposição problemas como apontou direções-chave que poderia explorar. Este fornece uma breve revisão da literatura sobre nas últimas três décadas, mostrando houve avanços marcantes na problemas. Fornecemos não apenas dos problemas, mas também do impacto O termina com discussão áreas específicas matemáticos (uma dessas é Aprendizagem Baseada em...