Marius A. Kemler

ORCID: 0000-0003-0306-1565
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About
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Research Areas
  • Pain Management and Treatment
  • Musculoskeletal pain and rehabilitation
  • Pain Mechanisms and Treatments
  • Transcranial Magnetic Stimulation Studies
  • Myofascial pain diagnosis and treatment
  • Orthopedic Surgery and Rehabilitation
  • Laser Applications in Dentistry and Medicine
  • Peripheral Nerve Disorders
  • Dupuytren's Contracture and Treatments
  • Migraine and Headache Studies
  • Nail Diseases and Treatments
  • Botulinum Toxin and Related Neurological Disorders
  • Surgical Sutures and Adhesives
  • Orthopaedic implants and arthroplasty
  • Nerve Injury and Rehabilitation
  • Anesthesia and Pain Management
  • Exercise and Physiological Responses
  • Tendon Structure and Treatment
  • Neurosurgical Procedures and Complications
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Cerebrospinal fluid and hydrocephalus
  • Musculoskeletal synovial abnormalities and treatments
  • Genital Health and Disease
  • Cardiac and Coronary Surgery Techniques
  • Orthopedic Infections and Treatments

Martini Ziekenhuis
2006-2025

University Medical Center Groningen
2022

Thomas Jefferson University
2022

Rothman Institute
2022

Rothman Orthopaedics
2022

Maastricht University Medical Centre
1999-2013

Maastricht University
1998-2008

University of Amsterdam
2001-2007

Amsterdam UMC Location University of Amsterdam
2007

Medisch Centrum Leeuwarden
2003

Chronic reflex sympathetic dystrophy (also called the complex regional pain syndrome) is a painful, disabling disorder for which there no proven treatment. In observational studies, spinal cord stimulation has reduced associated with disorder.

10.1056/nejm200008313430904 article EN New England Journal of Medicine 2000-08-31

Object Chronic complex regional pain syndrome–Type I (CRPS-I) is a painful, disabling disorder for which no treatment with proven effect available. In the present randomized controlled trial, authors assessed effectiveness of spinal cord stimulation (SCS) in reducing due to CRPS-I at 5-year follow-up. Methods The performed trial 2:1 ratio 36 patients were allocated receive SCS and physical therapy (PT) 18 PT alone. Twenty-four who received SCS+PT also underwent placement permanent stimulator...

10.3171/jns/2008/108/2/0292 article EN Journal of neurosurgery 2008-02-01

Abstract Chronic reflex sympathetic dystrophy is a painful, disabling disorder for which no treatment with proven effect available. We performed randomized trial in 2 to 1 ratio of patients, 36 patients were treated spinal cord stimulation and physical therapy (SCS+PT), 18 received solely PT. Twenty‐four SCS+PT given permanent system after successful test stimulation; the remaining 12 system. assessed pain intensity, global perceived effect, functional status, health‐related quality life....

10.1002/ana.10996 article EN Annals of Neurology 2003-12-30

<b><i>Objective: </i></b> To evaluate the economic aspects of treatment chronic reflex sympathetic dystrophy (RSD) with spinal cord stimulation (SCS), using outcomes and costs care before after start treatment. <b><i>Methods: Fifty-four patients RSD were randomized to receive either SCS together physical therapy (SCS+PT; n = 36) or alone (PT; 18). Twenty-four SCS+PT responded positively trial underwent implantation. During 12 months follow-up, (routine costs, out-of-pocket costs) effects...

10.1212/01.wnl.0000028686.74056.e3 article EN Neurology 2002-10-22

Background A randomized trial was performed to assess the effect of spinal cord stimulation (SCS) on detection and pain thresholds for pressure, warmth, cold extent mechanical hyperalgesia in patients with chronic complex regional syndrome type I. Methods Fifty-four I were receive both SCS physical therapy (SCS+PT; n = 36), or only (PT; 18). Twenty-four SCS+PT responded positively underwent implantation. During a 12-month follow-up period, six quantitative sensory testing sessions performed....

10.1097/00000542-200107000-00016 article EN Anesthesiology 2001-07-01

Reflex sympathetic dystrophy (RSD) is a relatively common disabling disorder of unknown pathophysiology. From cohort 52 patients, carefully selected to fulfill the recently formulated diagnostic criteria for RSD, venous blood samples were taken typing class I and II major histocompatibility antigens. The frequency HLA-DQ1 was found be significantly increased compared with control frequencies. association provides an indication organic basis RSD.

10.1212/wnl.53.6.1350 article EN Neurology 1999-10-01

To study what happens in a family where one member suffers from chronic pain, we quantitatively assessed the effect of pain resulting complex regional syndrome type 1 (CRPS) on 1) employment status, 2) time allocation, 3) additional domestic help, and 4) out-of-pocket expenses Dutch patients (n = 50) their spouses 43). This is first to measure allocation by means diary assessment technique. The results were compared with normative values for population overall. In households containing male...

10.1016/s0885-3924(02)00386-x article EN publisher-specific-oa Journal of Pain and Symptom Management 2002-05-01

Background Spinal cord stimulation (SCS) is known to relieve pain in patients with complex regional syndrome (CRPS) and, general, cause vasodilation. The vasodilatory effect of SCS hypothesized be secondary inhibition sympathetically mediated vasoconstriction, or through antidromic impulses resulting release vasoactive substances. aim the present study was assess whether relief CRPS after is, fact, dependent on In addition, we tried determine which potential mechanisms may that generally...

10.1097/00000542-200006000-00024 article EN Anesthesiology 2000-06-01

Objective To investigate the degree of pain reduction in patients with complex regional syndrome type 1 (CRPS 1) that can be defined as "successful." Design All rated their on a visual analog scale (VAS; 0–10) before treatment and three occasions after treatment, at 6 months, year, 2 years. Patients also Global Perceived Effect (GPE) for relief same time periods. The GPE items were classified "successful" or "unsuccessful." mean absolute relative (using VAS) was calculated both...

10.1097/00002508-200309000-00001 article EN Clinical Journal of Pain 2003-08-21

Spinal cord stimulation (SCS) has proven to be an effective however invasive and relatively expensive treatment of chronic Complex Regional Pain Syndrome type 1(CRPS-1). Furthermore, in one third CRPS-1 patients, SCS fails give significant pain relief 32-38% treated patients experience complications. The aim the current study was develop prognostic factors for prediction successful outcome SCS.The population consisted 36 CRPS enrolled a randomized controlled trial efficacy. We analyzed...

10.1016/j.ejpain.2009.10.009 article EN European Journal of Pain 2009-11-28

Before surgery for Dupuytren's contracture, 54 patients with a proximal interphalangeal (PIP) joint flexion contractures of at least 30° were randomized to receive either 3-month splinting protocol together hand therapy under the direct supervision therapists, or same alone. Extension deficit PIP (primary outcome measure), global perceived effect, pain intensity, comfort and complications assessed baseline 1 year after surgery. In an intention-to-treat analysis, group assigned...

10.1177/1753193412437631 article EN Journal of Hand Surgery (European Volume) 2012-02-06

The aim of this study was to find out which aspects health-related quality life (HRQL), measured with generic instruments, are important patients reflex sympathetic dystrophy (RSD) affecting the arm or leg. Sickness Impact Profile 68 (SIP68), Nottingham Health (NHP), and EuroQol-5D (EQ-5D) were completed by 54 suffering from RSD (33 arm, 21 leg). scores three questionnaires for an affected leg presented. Aspects relevant include NHP1 dimensions pain (mean score: 63%), sleep (58%), energy...

10.1016/s0885-3924(00)00170-6 article EN publisher-specific-oa Journal of Pain and Symptom Management 2000-07-01

A male patient in his 50s presented with severe bilateral wrist pain caused by scapholunate advanced collapse (SLAC). He did not wish to undergo a salvage treatment, and consecutively both affected scaphoids were replaced 3D-modelled prostheses. 3 2 years postoperatively, the had significant reduction, good function grip strength. Final X-rays demonstrated no signs of dislocation implant or periprosthetic arthritis. Studies have shown that once SLAC occurs, treatment should consist either...

10.1136/bcr-2024-264761 article EN BMJ Case Reports 2025-03-01

Background To diagnose sensory abnormalities, patient values can be compared with of the general population (absolute approach) or to measured at contralateral homologous skin (relative approach). The current study gives normal for both approaches and compares advantages each method by applying technique patients complex regional pain syndrome type I (CRPS I). Methods In 50 healthy control subjects, thresholds were pressure, warmth, cold on wrists feet. 53 unilateral CRPS (33 hand, 20 foot),...

10.1097/00000542-200009000-00021 article EN Anesthesiology 2000-09-01

The aim of the study was to assess retrospectively clinical efficacy and possible adverse effects electrical spinal cord stimulation (SCS) for treatment patients with reflex sympathetic dystrophy (RSD).Twenty-three who suffered severe pain due RSD were included in study. SCS system implanted only after a positive 1-week test period. visual analog scale (VAS) score (1-10) obtained all prior treatment, 1 month postimplantation, at last follow up. At final follow-up examination, asked rate...

10.3171/spi.1999.90.1.0079 article EN Journal of Neurosurgery Spine 1999-01-01

This study was designed to investigate whether Complex Regional Pain Syndrome type I (CRPS I) could be linked any previous infection.Fifty-two patients with CRPS of one extremity were screened for the presence antibodies against mostly neurotropic microorganisms.Of these 52 patients, none had Treponema pallidum, Borrelia burgdorferi, or HTLV-1. Only four positive Campylobacter jejuni. For cytomegalovirus, Epstein-Barr virus, herpes simplex and Toxoplasma gondii, seroprevalences similar...

10.1097/00002508-200106000-00002 article EN Clinical Journal of Pain 2001-06-01
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