- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- SARS-CoV-2 detection and testing
- Hepatitis C virus research
- Platelet Disorders and Treatments
- Hematopoietic Stem Cell Transplantation
- SARS-CoV-2 and COVID-19 Research
- Trauma and Emergency Care Studies
- Appendicitis Diagnosis and Management
- Emergency and Acute Care Studies
- Intraperitoneal and Appendiceal Malignancies
- Venous Thromboembolism Diagnosis and Management
- Hepatitis B Virus Studies
- Parvovirus B19 Infection Studies
- Blood groups and transfusion
- Respiratory Support and Mechanisms
- Ovarian cancer diagnosis and treatment
- Cardiovascular Effects of Exercise
- Congenital Heart Disease Studies
- COVID-19 Clinical Research Studies
- Biosensors and Analytical Detection
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular and Diving-Related Complications
- Complement system in diseases
Beth Israel Deaconess Medical Center
2024
Tufts Medical Center
2020-2023
Monroe Carell Jr. Children's Hospital
2013-2021
Phoenix Children's Hospital
2021
Vanderbilt University
2014-2021
Extracorporeal cardiopulmonary resuscitation (eCPR) has been well described as a rescue therapy in refractory cardiac arrest among patients with congenital heart disease. The purpose of this retrospective analysis data from the Life Support Organization was to evaluate outcomes eCPR structurally normal hearts and identify risk factors that may contribute mortality. During study period, 1,431 met inclusion criteria. Median age 16 years. Overall survival hospital discharge 32%. Conditional...
Therapeutic plasma exchange (TPE) removes both pathologic and protective immunoglobulins (Ig). SARS-CoV-2 immunity is partially mediated by anti-SARS-CoV-2 spike antibodies (SAb), which impair viral host-cell invasion. Nonetheless, the systematic effect of TPE on SAb concentration unknown.Paired waste specimens from first (first-TPE) last (last-TPE) treatment were collected 9 patients between July 21, 2021 March 1, 2022. The effects Ig levels assessed quantitatively comparing SAb, total IgG,...
Critical Care Medicine: December 2014 - Volume 42 Issue 12 p A1632 doi: 10.1097/01.ccm.0000458627.69262.b3
Background: Mechanical support to aid in restoration of circulation during cardiopulmonary resuscitation (CPR) is increasingly common the pediatric cardiac intensive care unit (CICU). We sought both identify and quantify factors predicting implementation extracorporeal membrane oxygenation CPR (eCPR). Methods Results: Events associated with from July 2010 through December 2013 within our CICU were retrospectively reviewed. Of 135 arrests among 88 patients, 84% postsurgical patients 98%...
Background: Econometric evidence suggests exponential declines in the ability to provide critical care services as variable demands exceed a relatively fixed supply of available resources. We hypothesized that increasing upon resources within pediatric cardiac intensive unit (CICU) is also associated with increases incidence and rate cardiopulmonary resuscitation. Methods Results: Records from each twelve-hour nursing shift an eighteen-bed CICU 1 July 2010 through 30 April 2014 were...
Introduction: Extracorporeal cardiopulmonary resuscitation (eCPR) has demonstrated success as a rescue therapy in refractory cardiac arrest among patients with congenital heart disease. Outcome predictors eCPR-supported structurally normal hearts are less well defined. Methods: Life Support Organization (ELSO) registry data was retrospectively reviewed from January 1998 through December 2011. Patients an ICD-9 diagnosis code consistent structural disease were excluded. The remaining subjects...