Lining Zhao

ORCID: 0000-0003-0311-7856
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About
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Research Areas
  • Protein Interaction Studies and Fluorescence Analysis
  • Selenium in Biological Systems
  • Quantum Dots Synthesis And Properties
  • Effects and risks of endocrine disrupting chemicals
  • Toxic Organic Pollutants Impact
  • Supercapacitor Materials and Fabrication
  • Conducting polymers and applications
  • Nanoparticles: synthesis and applications
  • Nanoparticle-Based Drug Delivery
  • Drug Transport and Resistance Mechanisms
  • Heavy Metal Exposure and Toxicity
  • Per- and polyfluoroalkyl substances research
  • Polymer Surface Interaction Studies
  • Microplastics and Plastic Pollution
  • Nanocluster Synthesis and Applications
  • Mechanical Engineering and Vibrations Research
  • Chalcogenide Semiconductor Thin Films
  • Advanced Sensor and Energy Harvesting Materials
  • Elasticity and Wave Propagation
  • Advancements in Battery Materials
  • Carcinogens and Genotoxicity Assessment
  • Surfactants and Colloidal Systems
  • Methemoglobinemia and Tumor Lysis Syndrome
  • Mercury impact and mitigation studies
  • Dye analysis and toxicity

Hebei University
2020-2025

Lanzhou University
2023-2025

Shandong University
2015-2020

China University of Petroleum, East China
2019-2020

In-Q-Tel
2018

Xi'an Polytechnic University
2006

Metal-doped carbon dots (CDs) exhibited promising application in fluorescence and magnetic resonance (MR) imaging, but developing manganese-doped CDs (Mn-CDs) with long wavelength emission enhanced MR performance is a challenge. Herein, using one-step solvothermal method, Mn-CDs redshifted orange longitudinal relaxation were synthesized for imaging. The results indicated that the prepared had uniform size distribution, average was 5 nm. Moreover, possessed stronger than Mn-free CDs,...

10.1021/acsabm.0c01597 article EN ACS Applied Bio Materials 2021-02-04

Despite being one of the most world's widely used and mass-produced compounds, bisphenol A (BPA) has a wide range toxic effects. Bisphenol P (BPP), an alternative to BPA, been detected in many foods. The effects BPP dietary exposure on gut microbiota intestinal barrier were unclear. We designed three batches animal experiments: first studied mice exposed (30 µg/kg BW/day) for nine weeks found that they gained weight developed dysbiosis microbiota. second, using typical human levels (L, 0.3...

10.1016/j.envint.2023.107949 article EN cc-by-nc-nd Environment International 2023-04-25

Human serum albumin (HSA) was used as a model protein to explore the effects of brominated flame retardant (BFR) binding and corona formation on polystyrene nanoplastics (PNs). Under physiological conditions, HSA helped disperse PNs but promoted aggregates in presence tetrabromobisphenol A (TBBPA, ΔDh = 135 nm) S (TBBPS, 256 at pH 7. At 4, these became larger with fewer electrostatic repulsion (ΔDh 920 691 nm for TBBPA TBBPS, respectively). However, such promotion well BFR are different due...

10.1021/acs.est.2c09090 article EN Environmental Science & Technology 2023-03-09

The toxic mechanism of cadmium-quantum dots (Cd-QDs) to organisms is still debating. In this paper, it was found that Cd-QDs could induce adverse effects kidney by entering into cells in a time and dose manner disturbing the redox balance vivo. As selenium containing protein, glutathione peroxidase3 (Gpx3) plays crucial role maintaining system. decrease Gpx3 activity might be related imbalance Similar animal results, demonstrated also inhibited vitro. To investigate underlying on...

10.1093/toxsci/kfy297 article EN Toxicological Sciences 2018-12-07

10.1016/j.jphotobiol.2016.08.011 article EN Journal of Photochemistry and Photobiology B Biology 2016-08-11

Gold nanoclusters (AuNCs) with an ultrasmall size showed potential application in photodynamic therapy (PDT), but short circulation and weak tumor retention restricted their PDT performance. Herein, bovine serum albumin (BSA) nanospheres good biocompatibility were used to encapsulate AuNCs, by which the stable biocompatible AuNCs@BSA nanoprobes synthesized boost The results that AuNCs a of 1.5 nm encapsulated BSA nanospheres, prepared nanoparticles average 120 have high colloid stability...

10.1021/acsanm.1c03209 article EN ACS Applied Nano Materials 2021-12-02

The electrochemical performance of the carbon cloth (CC)-based electrodes is determined by kind, content, morphology, and size modified pseudocapacitive materials, as well interaction with CC. Also, such structural parameters were mainly dependent on deposition condition. More uniform polyaniline (PANI) could be obtained polymerization in comparison to chemical oxidation polymerization. However, two steps electrodeposition usually needed for nucleation growth. Here, based comprehensive...

10.1021/acs.langmuir.3c01594 article EN Langmuir 2023-09-27

Alizarin red S is confirmed to be toxic catalase at molecular level attributing the structural and functional changes of catalase.

10.1039/c9ra02986a article EN cc-by RSC Advances 2019-01-01

ABSTRACT Polypropylene (PP) membranes show promising applications in electric and biomedical fields. However, the residue of Z–N catalyst system would decline their electrical properties, limiting practical applications. To explore transition migration propylene polymerization, as‐synthesized PP granules are extracted with polar solvent (ethanol) nonpolar ( n ‐hexane) respectively. The extracts quantitatively analyzed 1 H NMR technique. results demonstrate that donors low‐molecular‐weight...

10.1002/app.56878 article EN Journal of Applied Polymer Science 2025-02-20

To research the mechanism of dimercaptosuccinic acid coated-superparamagnetic iron oxide nanoparticles (SPION) with human serum albumin (HSA), methods spectroscopy, molecular modeling calculation, and calorimetry were used in this paper. The inner filter effect fluorescence intensity was corrected to obtain accurate results. Ultraviolet-visible absorption circular dichroism spectra reflect that SPION changed secondary structure a loss α-helix loosened protein skeleton HSA; activity also...

10.1002/jbt.21731 article EN Journal of Biochemical and Molecular Toxicology 2015-08-04

There is a severe lack of understanding the effects micro/nanoplastics on human proteins and cells, especially in presence organic pollutants. Herein, both vivo vitro assays are conducted to structurally evaluate blood protein complexed with perfluorooctanoic acid (PFOA) perfluorooctane sulfonate (PFOS) as well their coronas formed polystyrene nanoplastics (PNs). PFOS bound serum albumin (SA) about 4 times firmly PFOA, which not influenced by corona formation onto PN surfaces. However, small...

10.1002/smsc.202400255 article EN cc-by Small Science 2024-09-23

Abstract Maltol is a flavor additive that widely used in the daily diet of humans, and its biosafety attention concomitantly increasing. Catalase (CAT) an antioxidant enzyme to maintain homeostasis tissue's environment human body protect cells from oxidative damages. The adverse effects maltol CAT activity within mouse hepatocytes as well structural functional changes on molecular level were investigated by multiple spectroscopy techniques, experiments, docking. Results suggested when...

10.1002/jmr.2822 article EN Journal of Molecular Recognition 2019-11-06

Plant WRKY genes encode a complex and ancient class of zinc-finger transcription factors that are involved in multiple biological processes, especially regulating defense against abiotic stresses. Despite growing number studies on the genomic organization gene family various species, little information is available about this hemp (Cannabis sativa L.). In study, based genome sequence, 40 (CsWRKY) were classified into three main groups five subgroups according to their orthologs Arabidopsis....

10.1007/s10535-016-0621-7 article EN Biologia Plantarum 2016-04-14

Copper ions enter the central group of catalytic center CRL and bind with CRL, resulting in a conformational change lipase. This turn causes an increase enzyme activity.

10.1039/c8tx00158h article EN Toxicology Research 2018-01-01
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