A5020343529- Migraine and Headache Studies
- Trigeminal Neuralgia and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Sympathectomy and Hyperhidrosis Treatments
- Neuropeptides and Animal Physiology
- Genetic Neurodegenerative Diseases
- Neurological Disorders and Treatments
- Heart Rate Variability and Autonomic Control
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Syncope and Autonomic Disorders
- Social and Educational Sciences
- Mitochondrial Function and Pathology
- Infectious Encephalopathies and Encephalitis
- Alcoholism and Thiamine Deficiency
- Neuroendocrine regulation and behavior
- Listeria monocytogenes in Food Safety
- Cardiovascular Health and Disease Prevention
- Microtubule and mitosis dynamics
- Infectious Diseases and Tuberculosis
- Ophthalmology and Eye Disorders
- Nitric Oxide and Endothelin Effects
- Acute Ischemic Stroke Management
- Bacterial Infections and Vaccines
Copenhagen University Hospital
2017-2025
Rigshospitalet
2016-2025
University of Copenhagen
2015-2025
Glostrup Hospital
2022-2023
Zealand University Hospital
2020
Herlev Hospital
2016-2018
Gentofte Hospital
2016-2018
Abstract Background Pituitary adenylate cyclase-activating polypeptide (PACAP), structurally related to vasoactive intestinal peptide (VIP), is one of the important mediators in pathogenesis migraine and known dilate cranial arteries induce headache migraine. Our objective was determine whether Lu AG09222—an investigational humanized monoclonal antibody directed against PACAP ligand—would inhibit PACAP-signaling cascade by abolishing its vasodilatory headache-inducing abilities. Methods In a...
Erenumab has demonstrated effectiveness for prevention of migraine attacks, but the treatment is costly, and a considerable proportion patients do not respond to it. The Registry Migraine study (REFORM) was initiated discover biomarkers that can predict response erenumab in with migraine. specific objective investigate differences efficacy based on clinical information, blood-based biomarkers, structural functional magnetic resonance imaging (MRI), intravenous infusion calcitonin...
Abstract Erenumab has proven effective for migraine prevention; however, a substantial proportion of people with do not benefit from treatment, and among those who do, there is considerable variability in response. This study aimed to identify clinical predictors therapeutic response erenumab evaluate their predictive value large cohort migraine. We conducted single-center, prospective, longitudinal adults migraine, experiencing ≥4 monthly days. All participants received 140 mg 24 weeks...
Background: Decreased endothelial function (EF) may be a prognostic marker for stroke. Measuring pharmacological effects on EF of interest in the development personalized medicine stroke prevention. In this study, we assessed reliability repeated measurements using pulse amplitude tonometry (PAT) technology acute patients. Similar, was tested healthy subjects devoid vascular disease to estimate reactivity and younger non-stroke population. Material Methods: EndoPAT2000 20 volunteers (men...
Abstract Soluble urokinase plasminogen activator receptor (suPAR) has garnered attention as a potential blood-based biomarker for low-grade chronic inflammation. However, its specific association with migraine, including subtypes, remains to be elucidated. We sought examine the of plasma suPAR levels migraine and subtypes. In this single-centre, cross-sectional study, was collected at single time point in adults sex-matched healthy controls from October 2020 June 2022. The quantification...
Encephalopathy and convulsive seizures are rare manifestations of metronidazole toxicity. The incidence is unknown, but the condition has most frequently been reported in patients their fifth to sixth decades. Usually, this regarded as reversible, permanent deficits even death have reported.A 66-year-old female patient undergoing treatment for pleural empyema was admitted our institution after her second episode seizure. Over course 1 week admittance, developed several along with progressive...
A 36-year-old nullipara at 35 weeks of gestation woke up with slurred speech and dysphagia. The next day, she developed abruption the placenta, underwent an acute cesarean, was diagnosed severe preeclampsia. Neurologic examination revealed flaccid dysarthria, bilateral soft palate palsy, reduced taste left posterior tongue, left-sided tongue deviation, paralysis sternocleidomastoid trapezius muscles. MRI edema compatible hypoglossal nerve denervation electromyography glossal muscles showed...