- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural and Behavioral Psychology Studies
- Heart Rate Variability and Autonomic Control
- Mindfulness and Compassion Interventions
- Attention Deficit Hyperactivity Disorder
- EEG and Brain-Computer Interfaces
- Optical Imaging and Spectroscopy Techniques
- Functional Brain Connectivity Studies
- Olfactory and Sensory Function Studies
- Opioid Use Disorder Treatment
- Hallucinations in medical conditions
- Pain Mechanisms and Treatments
- Psychosomatic Disorders and Their Treatments
- Acupuncture Treatment Research Studies
- Currency Recognition and Detection
- Musculoskeletal pain and rehabilitation
- Medical Research and Treatments
- Cardiovascular and exercise physiology
- Vagus Nerve Stimulation Research
- Child and Adolescent Psychosocial and Emotional Development
- Pain Management and Placebo Effect
- Biochemical Analysis and Sensing Techniques
- Non-Invasive Vital Sign Monitoring
- Neural dynamics and brain function
- Eating Disorders and Behaviors
University of Utah
2020-2025
University of Tübingen
2016-2022
University Children's Hospital Tübingen
2018-2019
Universitätsklinikum Tübingen
2019
Children with attention-deficit/hyperactivity disorder (ADHD) suffer from attention deficits, motor hyperactivity, and impulsive behaviour. These impairments are experienced at home, school, friends. Functional imaging studies show that ADHD behaviour in executive functions (EFs) mirrored by aberrant neurophysiological functioning. Moreover, several behaviour, EFs, a lack of self-control contribute to poor school performance. Non-pharmacological interventions such as neurofeedback training...
Applying electrical stimulation over the prefrontal cortex can help nicotine dependents reduce cigarette craving. However, underlying mechanism remains ambiguous. This study investigates this issue with functional magnetic resonance imaging. Thirty-two male chronic smokers received real and sham dorsal lateral (DLPFC) separated by 1 week. The neuroimaging data of resting state, smoking cue-reactivity task emotion after were collected. craving across was diminished during as compared...
Based on neurofeedback (NF) training as a neurocognitive treatment in attention-deficit/hyperactivity disorder (ADHD), we designed randomized, controlled functional near-infrared spectroscopy (fNIRS) NF intervention embedded an immersive virtual reality classroom which participants learned to control overhead lighting with their dorsolateral prefrontal brain activation. We tested the efficacy of healthy adults displaying high impulsivity sub-clinical population sharing common features ADHD....
The current opioid crisis was fueled by escalation of dosing among patients with chronic pain. Yet, there are few evidence-based psychological interventions for dose reduction pain treated long-term analgesics. Mindfulness-Oriented Recovery Enhancement (MORE), which designed to target mechanisms underpinning and misuse, has shown promising results in 2 randomized clinical trials (RCTs) could facilitate sparing tapering bolstering self-regulation. Here we tested this hypothesis secondary...
Abstract Background Neuropsychopharmacologic effects of long-term opioid therapy (LTOT) in the context chronic pain may result subjective anhedonia coupled with decreased attention to natural rewards. Yet, there are no known efficacious treatments for and reward deficits associated use. Mindfulness-Oriented Recovery Enhancement (MORE), a novel behavioral intervention combining training mindfulness savoring rewards, hold promise treating LTOT. Methods Veterans receiving LTOT ( N = 63) were...
Self-regulation is instantiated by theta oscillations (4 to 8 Hz) in neurons of frontal midline brain regions. Frontal (FMΘ) inversely associated with default mode network (DMN) activation, which subserves self-referential processing. Addiction involves impaired self-regulation and DMN dysfunction. Mindfulness an efficacious self-regulatory practice for treating addiction, but little known about the mechanisms mindfulness reduces addictive behavior. In this mechanistic study long-term opioid...
Abstract Over the past decades, functional near‐infrared spectroscopy (fNIRS) has become a valuable tool in online assessment of brain function psychological and neuropsychiatric research. Recently, fNIRS also been employed context neurofeedback (NF), with pilot studies indicating that hemodynamic responses can be deliberately regulated neuroplastic changes occur over course several training sessions. This review article provides comprehensive overview recent implementation development as an...
Veterans experience chronic pain at greater rates than the rest of society and are more likely to receive long-term opioid therapy (LTOT), which, high doses, is theorized induce maladaptive neuroplastic changes that attenuate self-regulatory capacity exacerbate dose escalation. Mindfulness meditation has been shown modulate frontal midline theta (FMT) alpha oscillations linked with marked alterations in self-referential processing. These adaptive neural oscillatory may promote reduced use...
Ye, X, Hale, C, Brown, E, Clausi, Hudak, J, Marino, A, and Mezanko, T. Effects of percussion massage therapy on neuromuscular recovery from eccentric exercise-induced muscle damage. J Strength Cond Res XX(X): 000-000, 2025-The aim this study was to examine the effects intervention function performance Twenty healthy physically active volunteers underwent an elbow flexion exercise protocol (6 sets 10 repetitions with 80% concentric one-repetition maximum) their nondominant arms. The indirect...
Importance It remains unknown whether difficulties in positive emotion regulation (ER) drive opioid use disorder (OUD) and these may be remediated. Objective To test OUD is associated with attenuated ER such dysregulation treated by mindfulness-based intervention. Design, Setting, Participants In this mechanistic substudy of a randomized clinical trial, patients chronic pain who did not meet criteria for (OUD+ OUD-, respectively) were recruited from primary care clinics Utah January 2016 to...
Abstract Specific phobia is associated with aberrant brain activation in confrontation paradigms phobic stimuli. In previous EEG research enhanced event-related potentials (ERPs) the late-positive potential (LPP) window have been observed. Further, studies functional near-infrared spectroscopy (fNIRS) and fMRI suggest that spider within cortical subcortical areas. current study we investigated neuronal correlates of a combined fNIRS–EEG study. To this end, 37 patients (PP) 32 healthy...
In the current study, we investigate neuronal correlates of Attention Training Technique (ATT), a psychotherapeutic intervention used in metacognitive therapy to enhance flexible cognitive control and ameliorate rumination. We adapted ATT neuroscientific attention paradigm order effects its components: selective attention, switching divided comparison task. Functional near-infrared spectroscopy was measure changes blood oxygenation fronto-lateral parietal cortical areas. Furthermore,...
Depressive rumination is considered a prominent risk factor for the occurrence, severity, and duration of depressive episodes. A variety treatment options have been developed to treat which mindfulness based programs are especially promising. In current study, we investigated neural underpinnings short intervention mindful emotion regulation in high low trait ruminators an ecologically valid environment using functional near-infrared spectroscopy (fNIRS). Participants were randomly assigned...
Neurofeedback (NF) is a form of behavioral therapy used to treat e.g. attention-deficit/hyperactivity disorder (ADHD). Briefly, subjects are fed-back putatively dysfunctional parameter their brain activity in real time and must learn control it suggested direction. NF protocols for ADHD have been practice decades, though no clear standards on design implemented. Furthermore, studies often present only data from the general outcome treatment do not look at how exactly paradigm affects...
Exposure therapy is a well-studied and highly efficacious treatment for phobic disorders. Although the neurobiological model of fear well underpinned by various studies, mechanisms exposure are still under discussion. Partly, this due to fact that most neurophysiological methods like fMRI not able be used in natural therapeutic settings. The current study situ measurements cortical blood oxygenation (O2Hb) during means functional near-infrared spectroscopy. 37 subjects (N = 30 completers)...
Cue reactivity is an automatic reaction to alcohol-related cues, contributing the maintenance of drinking behavior and relapse in alcohol dependency. The identification valid cue-reactivity features a prerequisite for its clinical application. We were interested effects visual cues (e.g., color) on cue reactivity. Assuming development at pre-pathological stage, we analyzed heavy social drinkers, with light drinkers as controls. investigated whether was independent attentional (P100)...
Abstract. Children with attention deficit/hyperactivity disorder (ADHD) show deficient reading skills, which, like ADHD symptoms, are associated limitations in neurocognitive abilities. Neurofeedback (NF) aims to improve the latter, alleviate and promote school performances. Whether frontal lobe-NF based on functional near-infrared spectroscopy (fNIRS) electromyogram (EMG)-biofeedback (BF), however, abilities of children whether these changes abilities, has not yet been clarified. It was...