Jianjun Mu

ORCID: 0000-0003-0348-1164
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About
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Research Areas
  • Curcumin's Biomedical Applications
  • RNA modifications and cancer
  • Cancer-related molecular mechanisms research
  • Cardiac Ischemia and Reperfusion
  • Ubiquitin and proteasome pathways
  • Redox biology and oxidative stress
  • Sulfur Compounds in Biology
  • Microbial metabolism and enzyme function
  • Ginger and Zingiberaceae research
  • Cancer Mechanisms and Therapy
  • Circular RNAs in diseases
  • Peptidase Inhibition and Analysis
  • Genomics, phytochemicals, and oxidative stress
  • Organ Transplantation Techniques and Outcomes
  • Hydrogen's biological and therapeutic effects
  • Bioactive Compounds and Antitumor Agents

Shanxi Medical University
2024

First Affiliated Hospital of Xi'an Jiaotong University
2020-2021

LncRNA CCDC26 is aberrantly expressed in myeloid leukemia (ML) and promotes progression, but the potential mechanism of regulating ML progression unclear. In this study, we observed that lncRNA was upregulated both chronic acute cell lines. promoted proliferation invasion K562 HL-60 cells, which determined by counting kit-8 test Transwell assay. Flow cytometry showed inhibited apoptosis. Bioinformatics expression correlation analyses revealed there a interaction between CUGBP Elav-like...

10.1177/0963689720986080 article EN cc-by-nc Cell Transplantation 2021-01-01

The present study explored the therapeutic potential of hydrogen sulfide (H 2 S) in restoring aging-induced loss cardioprotective effect remote ischemic preconditioning (RIPC) along with involvement signaling pathways.The left hind limb was subjected to four short cycles ischemia and reperfusion (IR) young aged male rats induce RIPC.The hearts were IR injury on Langendorff apparatus after 24 h measurement lactate dehydrogenase, creatine kinase cardiac troponin served assess myocardial...

10.4196/kjpp.2021.25.3.239 article EN Korean Journal of Physiology and Pharmacology 2021-04-16

Tripartite motif-containing protein 24 (TRIM24) has currently emerged as a crucial cancer-related gene present in wide range of human cancer types. However, the involvement TRIM24 acute myeloid leukemia (AML) not been well investigated. The study aims to investigate significance, cellular function, and potential regulatory mechanism AML. We found that expression was significantly upregulated AML compared with normal tissues. patients low had higher survival rates than those expressing at...

10.1177/0960327120938845 article EN Human & Experimental Toxicology 2020-07-16

Objective: An excess of dietary salt is the most common environmental factor that contributes to development hypertension leading renal pathologies. Renalase (RNLS), a novel secreted flavoprotein with oxidoreductase activity, functions as survival and promotes cell organ survival. Previous evidence showed recombinant renalase exerts powerful hypotensive effects ameliorates interstitial fibrosis in rodents. In this study, we evaluated potential protective role underlying mechanisms...

10.1097/01.hjh.0000744888.84028.af article EN Journal of Hypertension 2021-04-01
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