- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Appendicitis Diagnosis and Management
- Genetic factors in colorectal cancer
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- Neuroendocrine Tumor Research Advances
- Intestinal Malrotation and Obstruction Disorders
- Gastrointestinal Bleeding Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Cancer Genomics and Diagnostics
- Dermatological and COVID-19 studies
- Cutaneous lymphoproliferative disorders research
- Uterine Myomas and Treatments
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Histiocytic Disorders and Treatments
- Endometriosis Research and Treatment
- Neuroblastoma Research and Treatments
- Diet and metabolism studies
- Ovarian cancer diagnosis and treatment
- Viral-associated cancers and disorders
Complejo Hospitalario Torrecárdenas
2021-2024
Hospital Universitario Araba
2019-2020
BioCruces Health research Institute
2020
Osakidetza
2020
Molecular lymph node (LN) staging in early colorectal cancer (CRC) has demonstrated to be more precise than conventional histopathology pN staging. Tumor budding (TB) and poorly differentiated clusters (PDCs) are associated with LN metastases, recurrences, lower survival CRC. We evaluated the correlation between total tumor load (TTL) LNs from CRC surgical specimens patient outcome, TB, PDC.In this retrospective multicentre study, 5,931 342 stage I-III were analyzed by both hematoxylin eosin...
The presence of lymph node (LN) metastasis is a critical prognostic factor in colorectal cancer (CRC) patients and also an indicator for adjuvant chemotherapy. gold standard (GS) technique LN diagnosis staging based on the analysis haematoxylin eosin (H&E)-stained slides, but its sensitivity low. As result, may not be properly diagnosed some have local recurrence or distant metastases after curative-intent surgery. Many these diagnostic treatment problems could avoided if one-step nucleic...
The use of epithelial cell adhesion molecule (EPCAM) immunohistochemistry (IHC) is not included in the colorectal cancer (CRC) screening algorithm to detect Lynch syndrome (LS) patients. aim present study was demonstrate that EPCAM IHC a useful tool guide LS germ-line analysis when loss MSH2 expression present. We retrospectively studied and large series 190 lesions composed malignant neoplasms (102), precursor gastrointestinal (71) extra-gastrointestinal origin (9), benign (8) from...
<title>Resumen</title> Introducción: Los tumores neuroendocrinos apendiculares (TNEa) tienen una incidencia de 0,97-1,4 casos por 100.000 habitantes año y el adenocarcinoma células caliciformes apendicular (ACCa) 0,01-0,05 año. A su vez, las neoplasias mixtas neuroendocrinas no (MiNEN) asientan en apéndice cecal (MiNENa) 52,9% los casos. Debido a infrecuencia, objetivo es analizar indicaciones quirúrgicas hemicolectomía derecha (HD) establecidas pronóstico dichas neoplasias. Material...
We present the third case described to date of large cell neuroendocrine carcinoma located at esophagogastric junction (LCNEC). Esophageal tumours account for 0.03-0.05% all malignant esophageal tumours. Within oesophageal NETs, LCNEC accounts 1% NETs. This tumour type is characterised by elevated levels certain markers: synaptophysin, chromogranin A and CD56. In fact, 100% patients will have or least one these three markers. turn, 78% lymphovascular invasion 26% perineural invasion. Only...
Although morphology is the key to histological diagnosis, gastric mesenchymal tumors can share very similar growth and cellularity patterns, sometimes being indistinguishable. Therefore, immunohistochemical techniques are going be crucial in definitive diagnosis. The objective of this work perform an differential diagnosis tumors.
<title>Resumen</title> La enfermedad por hígado graso no alcohólica supone un problema de salud creciente como consecuencia del aumento la obesidad y diabetes en población. Una causa poco común misma, pero que cada vez se diagnostica con más frecuencia, es secundaria a una duodenopancreatectomía cefálica. En estos casos los mecanismos fisiopatológicos son diferentes, aunque pueden acabar desarrollando igual manera progresiva. Por tanto, debe hacer seguimiento estrecho pacientes establecer...