A5086076096- Insect Resistance and Genetics
- Insect and Pesticide Research
- Insect Pest Control Strategies
- Insect-Plant Interactions and Control
- Environmental Toxicology and Ecotoxicology
- Neurobiology and Insect Physiology Research
- Pesticide and Herbicide Environmental Studies
- Pharmacogenetics and Drug Metabolism
- Insect Utilization and Effects
- African Botany and Ecology Studies
- Pesticide Exposure and Toxicity
- Entomopathogenic Microorganisms in Pest Control
- Drug Transport and Resistance Mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Viral Infectious Diseases and Gene Expression in Insects
- Insect and Arachnid Ecology and Behavior
- CRISPR and Genetic Engineering
- Bioeconomy and Sustainability Development
- Agriculture and Rural Development Research
- Beetle Biology and Toxicology Studies
- Plant Reproductive Biology
- Effects and risks of endocrine disrupting chemicals
- Allelopathy and phytotoxic interactions
- Renin-Angiotensin System Studies
- Biological Control of Invasive Species
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
1995-2025
Université Côte d'Azur
2005-2025
Centre National de la Recherche Scientifique
2013-2025
Institut Sophia Agrobiotech
2013-2024
Institut National de la Recherche Agronomique
1997-2013
Laboratoire de Biologie Intégrative des Modèles Marins
1990-2009
Laboratoire des Interactions Plantes Micro-Organismes
1997-2003
CNR de la Résistance aux Antibiotiques
1998-2001
Inserm
1995
Three point mutations R335S, L336V and V476L, distinguish the sequence of a cytochrome P450 CYP6A2 variant assumed to be responsible for 1,1,1-trichloro-2,2-bis-(4'-chlorophenyl)ethane (DDT) resistance in RDDT(R) strain Drosophila melanogaster. To determine impact each mutation on function CYP6A2, wild-type enzyme (CYP6A2wt) Cyp6a2 was expressed Escherichia coli as well three variants carrying single mutation, double mutant CYP6A2vSV triple CYP6A2vSVL. All were less stable than CYP6A2wt...
The cytochrome P450 gene Cyp6a2 from Drosophila melanogaster is located on the right arm of chromosome 2 at position 43A1-2 and comprises two exons separated by a 69-bp intron. Phenobarbital treatment flies leads to rapid increase in level CYP6A2 mRNA an increased production protein. DNA promoter region was functional when linked luciferase reporter transfected into D. Schneider cells. Moreover, dose-dependent induction activity phenobarbital indicated that elements necessary for are within...
Abstract The Eyguières 42 strain of Drosophila simulans, obtained by laboratory selection, displayed ∼ 20 000‐fold resistance to the insecticide fipronil. Molecular cloning cDNA encoding RDL GABA receptor subunit this revealed presence two mutations: Rdl mutation (A301G) and an additional in third transmembrane domain (T350M). In order assess individual combined roles mutations fipronil resistance, functional properties wild‐type, A301G, T350M A301G/T350M homomultimeric receptors were...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPyrethroid receptor in the insect sodium channel: alteration of its properties pyrethroid-resistant fliesDavid Pauron, Jacques Barhanin, Marcel Amichot, Madeleine Pralavorio, Jean Baptiste Berge, and Michel LazdunskiCite this: Biochemistry 1989, 28, 4, 1673–1677Publication Date (Print):February 21, 1989Publication History Published online1 May 2002Published inissue 21 February 1989https://doi.org/10.1021/bi00430a037RIGHTS & PERMISSIONSArticle...
Using pathogens or high levels of opportunistic bacteria to damage the gut, studies in Drosophila have identified many signaling pathways involved gut regeneration. Dying cells emit molecules that accelerate intestinal stem cell proliferation and progenitor differentiation replace dying quickly. This process has been named ‘regenerative death’. Here, mimicking environmental conditions, we show ingestion low was sufficient launch an accelerated cellular renewal program despite brief passage...
ou non, émanant des établissements d'enseignement et de recherche français étrangers, laboratoires publics privés.
Aphids respond to specific environmental cues by producing alternative morphs, a phenomenon called polyphenism, but also modulating their individual behavior even within the same morph. This complex plasticity allows rapid adaptation of individuals fluctuating conditions, underlying genetic and molecular mechanisms remain largely unknown. The foraging gene is known be associated with in various species has been shown mediate behavioral shift induced changes some insects. In this study, we...