This study aims to investigate the effectiveness of UIO-66-NH2, a metal-organic framework (MOF), as carrier for imipenem/cilastatin (Imp/Cil) in overcoming resistance clinical isolates imipenem-resistant Pseudomonas aeruginosa. The UIO-66-NH2-Imp/Cil formulations were synthesized and characterized using dynamic light scattering (DLS), scanning electron microscopy (SEM) transmission (TEM). Drug entrapment efficiency UIO-66-NH2-Imp/Cil, Imp/Cil release rates determined. stability was assessed...

Conventional antibacterial compounds can inhibit the growth of microorganisms, but their adverse effects and development drug limit widespread use. The current study aimed to synthesize PEG-coated UIO-66-NH

The focus of this study is on a rapid and cost-effective approach for the synthesis silver nanoparticles (AgNPs) using Artemisia quttensis Podlech aerial parts extract assessment their antioxidant, antibacterial anticancer activities. prepared AgNPs were determined by ultraviolet-visible spectroscopy, X-ray diffraction, Fourier transform infra-red transmission electron microscopy, scanning energy-dispersive dynamic light scattering zeta-potential analysis. A. evaluated antiradical scavenging...

The present study was to investigate the gas chromatography/mass spectrometry (GC/MS), in vitro antioxidant, antibacterial and anticancer activity of ethanolic extract from aerial parts Artemisia marschalliana Sprengel against human gastric carcinoma (AGS) L929 cell lines. Phytochemical analysis A. showed 22 major components most dominant compounds were trans-phytol (29.22%), α-Linolenic acid (13.47%) n-Hexadecanoic (9.28%). In addition, antioxidant evaluated using...

Silver nanoparticles (AgNPs) are at the forefront of swiftly developing scope nanotechnology. In current study, we investigated green synthesis AgNPs using Artemisia scoporia as a reducing and capping agent. The biosynthesized were characterized ultraviolet-visible spectroscopy, X-ray diffraction, Fourier-Transform infrared dispersive absorption scanning electron microscopy, transmission microscopy. efficacy nanoparticle was assessed by comparing antibiofilm activity with commercial AgNPs....

Background:Klebsiella pneumoniae is currently considered as an immediate threat to human health due its various multidrug efflux pumps. Microbially synthesized silver nanoparticles (AgNPs) are attractive and eco-friendly approach prevent antibiotic resistance in bacteria. In the present study, we compared inhibitory effect of both commercial green AgNPs by Bifidobacterium bifidum on OxqAB pump genes ciprofloxacin-resistant strains K. pneumoniae. Materials Methods: were characterized...

Abstract Background There is an increasing disease trend for SARS-COV-2, so need a quick and affordable diagnostic method. It should be highly accurate save costs compared to other methods. The purpose of this research achieve these goals. Methods This study analyzed 342 samples using TaqMan One-Step RT-qPCR fast RT-LAMP (Reverse Transcriptase Loop-Mediated Isothermal Amplification). LAMP assay was conducted assess the sensitivity specificity. Results reported positive two different In...

The effect of very low salt addition in the recommended liquid−liquid extraction chemical system toluene−acetone−water was investigated with circulating single drops and both mass transfer directions. By adding sodium chloride, potassium iodide, within concentration range 10−6−10−4 mol/L, into continuous phase under constant pH, rate finds enhancements to about 425%. A high trend variation observed for concentrations until only 10−5 mol/L. This phenomenon can be attributed hydration ions...

The present study aimed to design and characterize the L. casei-loaded niosomal formulation evaluate antitumor apoptotic efficacy of probiotic-loaded niosome against MCF7 cell line. Niosomal was synthesized using thin-layer hydration method, optimal synthesis confirmed dynamic light scattering (DLS), scanning electron microscopy (SEM), transmission (TEM). stability niosomes assessed for 30 days in two different storage environments. cytotoxicity experiment conducted on cancer line normal HFF...

Shallot from Liliacea are the oldest plants that used for treatment of different disease such as bacterial, parasitic, fungal infections and also viruses. In addition, Pseudomonas aeroginosa is most important human pathogen with invasive nature causes especially in cases abnormal defence. It resistant to many antibiotics, makes some problems treatment. This study was done evaluate effect shallot on pseudomonas aeroginosa. The undergoround bulbs this plant were percolated distilled water 7...

The present study aim to investigate the phytochemical composition, antibacterial, antioxidant and anticancer activities of ethanolic extract from aerial parts Artemisia quettensis Podlech. part A. Podlech was used for Gas chromatography-mass spectrometry (GC-MS) analysis, antioxidant, antibacterial activities. GC/MS analysis this plant showed 23 major components most dominant were acetic acid, [4-(1-hydroxy-1-methylethyl) cyclohex-1-enyl] methyl ester (13.88%), trans-Phytol (10.06%)...

Alternatives to conventional antibiotics are critical in light of the increasing prevalence antibiotic-resistant bacteria, posing a serious threat humanity and imposing financial burden on community. The current study aimed develop Vancomycin (Van) Gingerol (Gin) co-encapsulated niosomal (Nio-Gin/Van) formulation assess optimized as potent antibacterial agent against carbapenem-resistantKlebsiella pneumoniae(CRKP) strains. prepared Nio-Gin/Van was characterized via scanning electron...

Abstract Nanotechnology covers many disciplines, including the biological sciences. In this study, selenium nanoparticles (Se‐NPs) were synthesized using Artemisia annua extract and investigated against clinical strains of klebsiella pneumoniae ( K. ) for their anti‐biofilm effects. experimental from May 1998 to September 1998, 50 samples blood, urine, sputum collected, isolated microbiological methods. Subsequently, antibacterial effects Se‐NPs at concentrations 12‐25‐50‐100/5‐6/3‐25/125...

Uropathogenic Escherichia coli (UPEC) is one of the most common bacteria that can cause urinary tract infections (UTIs). Unfortunately, no human vaccine against UTIs has been developed. Therefore, it necessary to develop an efficient and safe able induce mucosal systemic immune responses. The use lactic acid as a delivery system promising method system.The aim this study was establish Lactobacillus reuteri harboring E. PapG antigen on its surface.In study, gene encoding fused AcmA (which...

In this study we have investigated removal of Zn and Ag Ions from aqueous solutions. Industrial pollutions by heavy metals ions as is a universal environmental problem, because their toxicity. Thus, studied these NH₂-MCM-41 nano porous adsorbent at room temperature. This has high surface area, adsorption ability, factor porosity wide porous. the batch experiment taken 150 cm^-3 considered metallic ion solution. After pH adjustment, absorbent was added it agitated rotary...