- Plant Molecular Biology Research
- Plant nutrient uptake and metabolism
- Evolution and Genetic Dynamics
- Plant Reproductive Biology
- Genetic diversity and population structure
- Gene Regulatory Network Analysis
- Plant Physiology and Cultivation Studies
- Plant Virus Research Studies
- Genomics and Phylogenetic Studies
- Microbial Metabolic Engineering and Bioproduction
- Plant tissue culture and regeneration
- Microtubule and mitosis dynamics
Utrecht University
2017-2024
Wood constitutes the largest reservoir of terrestrial biomass. Composed xylem, it arises from one side vascular cambium, a bifacial stem cell niche that also produces phloem on opposing side. It is currently unknown which molecular factors endow cambium identity. Here we show TRACHEARY ELEMENT DIFFERENTIATION INHIBITORY FACTOR (TDIF) ligand-activated PHLOEM INTERCALATED WITH XYLEM (PXY) receptors promote expression CAMBIUM-EXPRESSED AINTEGUMENTA-LIKE (CAIL) transcription to define identity in
Changing environmental conditions pose a challenge for the survival of species. To meet this organisms adapt their phenotype by physiological regulation (phenotypic plasticity) or evolving. Regulatory mechanisms that ensure constant internal environment in face continuous external fluctuations (homeostasis) are ubiquitous and essential survival. However, more drastic enduring change, often requires lineages to mutating. In vitro evolutionary experiments with microbes show adaptive, large...
Abstract Background Mutators are common in bacterial populations, both natural isolates and the lab. The fate of these lineages, which mutation rate is increased up to 100 ×, has long been studied using population genetics models, showing that they can spread a following an environmental change. However stable conditions, suffer from mutational load, hence being overcome by non-mutators. However, results don’t take into account fact elevated impact genetic structure, changing sensitivity...
After germination, the meristem of embryonic plant root becomes activated, expands in size and subsequently stabilizes to support post-embryonic growth. The hormones auxin cytokinin, together with master transcription factors PLETHORA (PLT) family have been shown form a regulatory network that governs patterning this meristem. Still, which functional constraints contributed shaping dynamics architecture network, has largely remained unanswered. Using combination modeling approaches we reveal...