A.F. Ribeiro

ORCID: 0000-0003-0373-9890
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About
Contact & Profiles
Research Areas
  • Cystic Fibrosis Research Advances
  • Inhalation and Respiratory Drug Delivery
  • Neonatal Respiratory Health Research
  • Tissue Engineering and Regenerative Medicine
  • Muscle Physiology and Disorders
  • Tracheal and airway disorders
  • Infant Development and Preterm Care
  • Electrospun Nanofibers in Biomedical Applications
  • Congenital Anomalies and Fetal Surgery
  • Asthma and respiratory diseases
  • Pneumonia and Respiratory Infections
  • Pediatric health and respiratory diseases
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Clinical Nutrition and Gastroenterology
  • Child Nutrition and Feeding Issues
  • Congenital heart defects research
  • Genetics, Aging, and Longevity in Model Organisms
  • Healthcare Regulation
  • Dental Trauma and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Silk-based biomaterials and applications
  • Folate and B Vitamins Research
  • Biological Research and Disease Studies
  • Intestinal Malrotation and Obstruction Disorders
  • Dental Health and Care Utilization

Universidade de São Paulo
2016-2025

Hospital Regional de Presidente Prudente
2024

Universidade Estadual de Campinas (UNICAMP)
2004-2023

Hospital de Clínicas da Unicamp
2008-2023

PluriCell (Brazil)
2021

Biotech (Brazil)
2021

Universidade Federal de Minas Gerais
2021

Stem Cell Institute
2016

Masaryk University
2008

Abstract Satellite cells (SCs) are the main muscle stem responsible for its regenerative capacity. In muscular dystrophies, however, a failure of process results in degeneration and weakness. To analyze effect different degrees SCs behavior, we studied adult dystrophic strains: DMD mdx , Large myd / with variable histopathological alterations. Similar were observed models, which maintained normal levels PAX7 expression, retained Pax7-positive pool, their proliferation Moreover, elevated...

10.1038/s41598-019-48156-7 article EN cc-by Scientific Reports 2019-08-14

Abstract Background Measurements of CFTR function in rectal biopsies ex vivo have been used for diagnosis and prognosis Cystic Fibrosis (CF) disease. Here, we aimed to evaluate this procedure regarding: i) viability the specimens obtained by biopsy forceps bioelectrical biochemical laboratory analyses; ii) overall assessment (comfort, invasiveness, pain, sedation requirement, etc.) from patients perspective assess its feasibility as an outcome measure clinical trials. Methods We compared...

10.1186/1471-230x-13-91 article EN cc-by BMC Gastroenterology 2013-05-20

Objective: To analyze the characteristics of cystic fibrosis (CF) care centers (CFCCs) in Brazil. Methods: A questionnaire was sent to coordinators all 51 registered CFCCs between May and September 2021. Results: The response rate 100%. Southeastern Brazil is region where most country are located (21 centers; 41%), followed by southern northeastern regions (11 each; 21.5%), central-western (6; 12%), northern (2; 4%). total 4,371 patients with CF were cared for during study period, ranging...

10.36416/1806-3756/e20220306 article EN cc-by-nc Jornal Brasileiro de Pneumologia 2023-01-10

The mdx mouse is a good genetic and molecular murine model for Duchenne Muscular Dystrophy (DMD), progressive devastating muscle disease. However, this inappropriate testing new therapies due to its mild phenotype. Here, we transferred the mutation 129/Sv strain with aim create more severe DMD. Unexpectedly, functional analysis of first three generations mdx129 showed amelioration phenotype, associated less connective tissue replacement, regeneration than original mdxC57BL. Transcriptome...

10.1371/journal.pone.0150748 article EN cc-by PLoS ONE 2016-03-08

The scant ability of cardiomyocytes to proliferate makes heart regeneration one the biggest challenges science. Current therapies do not contemplate re-muscularization. In this scenario, stem cell-based approaches have been proposed overcome lack regeneration. We hypothesize that early-stage hiPSC-derived (hiPSC-CMs) could enhance cardiac function rats after myocardial infarction (MI). Animals were subjected permanent occlusion left ventricle (LV) anterior descending coronary artery (LAD)....

10.3390/jpm11050374 article EN Journal of Personalized Medicine 2021-05-04

To determine whether abnormal continuous glucose monitoring (CGM) readings (hypoglycemia/hyperglycemia) can predict the onset of cystic fibrosis-related diabetes (CFRD) and/or clinical impairment (decline in BMI FEV1) pediatric patients with fibrosis (CF).This was a longitudinal prospective cohort study involving CF without at baseline. The mean follow-up period 3.1 years. underwent 3-day CGM, performed oral tolerance test (OGTT), and had FEV1 determined OGTT, FEV1, were reassessed end...

10.36416/1806-3756/e20210307 article EN cc-by-nc Jornal Brasileiro de Pneumologia 2022-04-30

Abstract The scant ability of cardiomyocytes to proliferate makes heart regeneration one the biggest challenges science. Current therapies do not contemplate re-muscularization. In this scenario, stem cell-based approaches have been proposed overcome lack regeneration. We hypothesize PluriCell hiPSC-derived (hiPSC-CMs) could enhance rat’s cardiac function after myocardial infarction (MI). Animals were subjected permanent occlusion Left-Ventricle (LV) anterior descending coronary artery...

10.1101/2021.03.09.434658 preprint EN cc-by-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-03-10
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