Lexiang Zhang

ORCID: 0000-0003-0374-4382
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Biosensors and Analytical Detection
  • Microfluidic and Capillary Electrophoresis Applications
  • Advanced biosensing and bioanalysis techniques
  • Lipid Membrane Structure and Behavior
  • Proteins in Food Systems
  • CRISPR and Genetic Engineering
  • MicroRNA in disease regulation
  • Heat Transfer and Boiling Studies
  • Extracellular vesicles in disease
  • Advancements in Transdermal Drug Delivery
  • Curcumin's Biomedical Applications
  • Fluid Dynamics and Mixing
  • Viral Infections and Immunology Research
  • Nanoparticle-Based Drug Delivery
  • Advanced Nanomaterials in Catalysis
  • Wound Healing and Treatments
  • Pickering emulsions and particle stabilization
  • RNA Interference and Gene Delivery
  • Electrowetting and Microfluidic Technologies
  • Nanoplatforms for cancer theranostics
  • Bone Tissue Engineering Materials
  • Endometriosis Research and Treatment
  • Dendrimers and Hyperbranched Polymers
  • Orbital Angular Momentum in Optics

University of Chinese Academy of Sciences
2022-2025

Zhejiang Lab
2022-2025

Wenzhou Medical University
2022-2025

First Affiliated Hospital of Wenzhou Medical University
2022-2025

Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2024-2025

Wenzhou University
2024

Nanjing Drum Tower Hospital
2022

China University of Geosciences
2022

Harvard University
2019

Harvard University Press
2019

Platinum drugs have been coined as one of the great success representatives in cancer chemotherapy. With accidental discovery cisplatin, thousands platinum-based complexes synthesized, including clinically approved classical platinum(II) (Pt(II)) drugs, non-classical Pt(II) and platinum(IV) (Pt(IV)) drugs. Currently, these are widely utilized treatment various solid tumors clinic. Unfortunately, systemic toxicity innate or acquired drug resistance greatly restrict their applications. The...

10.1016/j.bmt.2022.11.011 article EN cc-by-nc-nd Biomedical Technology 2022-12-17

Abstract Exosomal microRNAs have been studied as a good source of noninvasive biomarkers due to their functions in genetic exchange between cells and already well documented many biological activities; however, inaccuracy remains key challenge for liver cancer surveillance. Herein, versatile duplex photothermal digital polymerase chain reaction (PCR) strategy combined with lipid nanoparticle‐based exosome capture approach is proposed profile expression through 3‐h easy‐to‐operate process....

10.1002/smll.202207672 article EN Small 2023-03-21

Abstract Exosomes are cell‐derived extracellular vesicles which enclose genetic substances from their origin cells, offering a good source of biomarkers. Many efforts have been made to develop non‐invasive exosome‐based clinical diagnosis, urgently needed for prostate cancer, as traditional methods criticized due the inaccuracy and discomfort. In this study, simple, universal process genotyping exosome‐derived microRNAs using nanoparticles capture exosomes novel photothermal droplet digital...

10.1002/adfm.202207879 article EN Advanced Functional Materials 2022-09-28

Abstract The unprecedented demand for variants diagnosis in response to the COVID‐19 epidemic has brought spotlight onto rapid and accurate detection assays single nucleotide polymorphisms (SNPs) at multiple locations. However, it is still challenging ensure simplicity, affordability, compatibility with multiplexing. Here, a novel technique presented that combines peptide nucleic acid (PNA) clamps near‐infrared (NIR)‐driven digital polymerase chain reaction (dPCR) identify Omicron Delta...

10.1002/advs.202306088 article EN cc-by Advanced Science 2024-01-19

Abstract The performance and safety of lithium (Li) metal batteries can be compromised owing to the formation Li dendrites. Here, use a polymer intrinsic microporosity (PIM) is reported as feasible robust interfacial layer that inhibits dendrite growth. PIM demonstrates excellent film‐forming ability, electrochemical stability, strong adhesion copper electrode, outstanding mechanical flexibility so it relieves stress structural changes produced by reversible lithiation. Importantly, porous...

10.1002/chem.201902124 article EN Chemistry - A European Journal 2019-07-03

Endometriosis is marked by the ectopic growth, spread, and invasion of endometrial tissue beyond uterus, resulting in recurrent bleeding, pain, reproductive challenges, formation nodules or masses. Despite advancements detection methods like ultrasound laparoscopy, these techniques remain limited low specificity invasiveness, underscoring need for a highly specific, noninvasive vitro diagnostic method. This study investigates potential using menstrual blood as sample endometriosis targeting...

10.34133/research.0652 article EN cc-by Research 2025-01-01

A chemiluminescence enzyme immunoassay based on microfluidic magnetic droplets for multiplex sepsis biomarker screening, which has great potential broader applications in biomolecule detection and early disease diagnosis, is reported.

10.1039/d4an01253d article EN The Analyst 2025-01-01

Abstract Homogeneous catalytic oxidations of cyclohexene by transition‐metal‐substituted phosphotungstates [PW 11 M(L)O 39 ] m− (PW M, M=Co II , Cu Fe III Ni Mn L=H 2 O or absence) with hydrogen peroxide in acetonitrile were experimentally studied. The activities allylic oxidation found to strongly depend on the transition metals, and PW Co showed highest activity. product distribution catalyst stability dominated mole ratio whereby low high ratios led stable structure M predominant...

10.1002/cctc.201700856 article EN ChemCatChem 2017-06-22
Coming Soon ...