A5020735860- Head and Neck Cancer Studies
- Tracheal and airway disorders
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Reconstructive Surgery and Microvascular Techniques
- Cancer Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Sinusitis and nasal conditions
- Reconstructive Facial Surgery Techniques
- Brain Metastases and Treatment
- Oral and Maxillofacial Pathology
- Phonetics and Phonology Research
- Cleft Lip and Palate Research
- Cancer and Skin Lesions
- Facial Trauma and Fracture Management
- Esophageal and GI Pathology
- Airway Management and Intubation Techniques
- Infectious Diseases and Mycology
- Pituitary Gland Disorders and Treatments
- Speech Recognition and Synthesis
- Facial Nerve Paralysis Treatment and Research
- Nasal Surgery and Airway Studies
- Vascular Tumors and Angiosarcomas
University of Turin
2016-2025
Ospedale San Giovanni Bosco
2022-2025
Ospedale Civile di Vittorio Veneto
2024
Ospedale San Luigi Gonzaga
2014-2022
Candiolo Cancer Institute
2009-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2022
University of Insubria
2022
Polytechnic University of Turin
2022
Humanitas University
2021
Gonzaga University
2014
To develop a European White Paper document on oropharyngeal dysphagia (OD) in head and neck cancer (HNC). There are wide variations the management of OD associated with HNC across Europe.
Objectives The aim of the present study was to investigate oncological and functional prognostic implication perioperative risk factors in elderly patient who underwent open partial horizontal laryngectomy (OPHL). Study Design A single institution, retrospective case–cohort study. Methods retrospectively reviewed clinical charts a cohort 100 laryngeal squamous cell carcinoma (LSCC) patients OPHL at our institution. Oncological results were evaluated through univariate analysis. Results...
BACKGROUND Some previous studies have shown that vinorelbine (VNB) is active in recurrent salivary gland tumors. METHODS Between April 1993 and 1997, 36 patients a Phase II randomized trial received either cisplatin, 80 mg/m2, on Day 1 plus VNB, 25 Days 8 (every 3 weeks) (for minimum of cycles (Arm A [16 patients]), or 30 mg/m2/week, 9 wks) B [20 patients]). There were 23 males 13 females with median age 59 years (range, 20–74 years) Eastern Cooperative Oncology Group performance status...
Abstract Background The purpose of this retrospective study was to identify subcategories in cT3 cT4a supraglottic/glottic cancers, describing their different spreading patterns, and local locoregional recurrence modes. Methods Four hundred eighty‐nine patients who underwent open partial horizontal laryngectomies (OPHLs) were retrospectively classified as: subcategory I (anterior pT3 with normal arytenoid mobility); II (posterior impaired/absent III pT4 IV mobility). Results Five‐year...
ABSTRACT Background Cancer of the larynx in intermediate/advanced stage still presents a major challenge terms controlling disease and preserving organ. Among therapeutic options, open partial horizontal laryngectomy is proposed as function‐sparing surgical technique. Methods We analyzed clinical outcomes 555 patients with laryngeal cancer staged pT3 to pT4a who underwent laryngectomy. Results Five‐year overall survival (OS), disease‐free (DFS), locoregional control, local laryngectomy‐free...
Laryngeal squamous cell carcinoma (SCC) accounts for 1.9% of cancers worldwide. Most these are diagnosed in the early stages (T1-T2, and N0). For these, a larynx preserving/conserving option is preferable. Beyond transoral laser microsurgery (TLM), open partial horizontal laryngectomy function-sparing surgical technique used to treat laryngeal SCC.We retrospectively analyzed clinical outcomes 216 patients who underwent glottic cT2 cancer.Five-year overall survival (OS), disease-specific...
Abstract Objective: The objective of this study was to describe a new subtotal laryngectomy technique that foresees two variations: 1) tracheohyoidopexy (THIP + A or A‐A)—subtotal removal the larynx maintaining one cricoarytenoid units and subsequent tracheohyoidopexy; 2) tracheohyoidoepiglottopexy (THIEP A‐A)—resection guarantees preservation suprahyoid epiglottis further suspension tracheal stump at hyoid bone. Methods: is described, step by step, extending laryngeal resection beyond...
Over the past three decades, incidence of oropharyngeal squamous cell carcinoma has increased, primarily related to spread human papillomavirus. Treatment always been preferentially unimodal (surgery or radiotherapy) for early stage disease and multimodal with adjuvant therapy concomitant chemoradiotherapy) advanced stages. Recently, surgical approach gained renewed interest due morbidity non-surgical treatments also technical innovations. We have coined term 3Des (3D exoscope surgery)...
Laryngeal cancer management should pursue function-sparing therapeutic options. Even though demolitive surgery provides better control of disease at intermediate to advanced stages when compared chemoradiotherapy, it does not preserve laryngeal function. Supratracheal partial laryngectomy has been described as a surgical technique for with subglottic extension.In this retrospective study, we analyzed the clinical outcomes 115 patients who underwent supratracheal laryngectomy.At 5 years,...
This study aimed to examine the relationship between sphenoid sinus (SS) and surrounding vital structures such as internal carotid artery (ICA) optic nerve canal (ONC) well types of attachment sphenoidal septa onto these structures.In total, 230 computed tomography (CT) scans were reviewed type pneumatization (SSP), protrusion dehiscence ICA ONC, pterygoid recess (PRP).The most common SSP was sellar (58.7%). The rates 26.3 0.4%, for they 13 1.5%, respectively. ONC protruded dehiscent in more...
Open partial horizontal laryngectomies (OPHLs) represent a valuable therapeutic option for tumors of the intermediate T-category and, in selected cases, locally advanced with low-volume extra-laryngeal extension. The eligibility patients treated this type surgery has increased introduction modular approach to OPHL planning. This strategy follows classification proposed by European Laryngological Society, based on extent resection. Optimization selection is result meticulous work-up process...
Background: Virtual surgical planning has become a well-established practice in head and neck surgery. In oncological surgery, it permits the achievement of safe margins resections ensures functional reconstructions optimal esthetic outcomes. This study aimed to evaluate long-term outcomes after virtually planned mandibular microvascular reconstruction, focusing on results, as well health-related quality life. Methods: A retrospective evaluation 17 patients with oral cavity malignancy who...
Recurrent or metastatic salivary gland malignancies (RMSGM) are not suitable for conventional treatment. We report the clinical outcomes of 60 patients affected by RMSGM who were treated with DDP+VNB as a first-line second-line scheme.Sixty between 2001 and 2008, enrolled in this cohort prospective study; they received following chemotherapy (CT), maximum 6 cycles: DDP at 80 mg/m on day 1+VNB 25 1 8, 3-week intervals.Seventy percent CT 30% them it CT. After 5 cycles (median) DDP+VNB, 7%...