A5070284946- Acute Kidney Injury Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Respiratory Support and Mechanisms
- Anesthesia and Pain Management
- Hemodynamic Monitoring and Therapy
- Enhanced Recovery After Surgery
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Muscle and Compartmental Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Hip and Femur Fractures
- Health and Lifestyle Studies
- Digital Imaging in Medicine
- Ear Surgery and Otitis Media
- Pain Mechanisms and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pleural and Pulmonary Diseases
- Pediatric Pain Management Techniques
- Mast cells and histamine
Clinica Universidad de Navarra
2008-2017
Gobierno de Navarra
2015
Universidad de Navarra
2005-2011
<i>Background:</i> The optimal time to initiate renal replacement therapy (RRT) in cardiac surgery-associated acute kidney injury (CSA-AKI) is unknown. Evidence suggests that the early use of RRT critically ill patients associated with improved outcomes. We studied effects initiation on outcome CSA-AKI. <i>Methods:</i> This was a retrospective observational multicenter study (24 Spanish hospitals). analyzed data 203 who required after surgery 2007. cohort divided into...
Acute kidney injury is among the most serious complications after cardiac surgery and associated with an impaired outcome. Multiple factors may concur in development of this disease. Moreover, severe renal failure requiring replacement therapy (RRT) presents a high mortality rate. Consequently, we studied Spanish cohort patients to assess risk for RRT surgery-associated acute (CSA-AKI).A retrospective case-cohort study 24 hospitals. All cases 2007 were matched crude ratio 1:4 consecutive...
Abstract Background The aim of this study is to evaluate the association between acute serum creatinine changes in renal failure (ARF), before specialized treatment begins, and in-hospital mortality, recovery function, overall mortality at 6 months, on an equal degree ARF severity, using RIFLE criteria, comorbid illnesses. Methods Prospective cohort 1008 consecutive patients who had been diagnosed as having ARF, admitted university-affiliated hospital over 10 years. Demographic, clinical...
Purpose Cardiac surgery-associated acute kidney injury requiring renal replacement therapy (RRT) is independently associated with mortality. Several risk scores have been developed to predict the need for RRT after cardiac surgery. We compared and verified external validity of three main available prediction surgery: Thakar score, Mehta tool, Simplified Renal Index. Methods The were calculated in a cohort 1084 adult patients, 248 whom required RRT, who underwent open-heart surgery 24 Spanish...
Patients undergoing lung surgery are at risk of postoperative pulmonary complications (PPCs). Identifying those patients is important to optimise individual perioperative management. The Clinical Prediction Rule for Pulmonary Complications (CPRPCs) after thoracic surgery, developed by the Memorial Sloan-Kettering Cancer Center, might be an ideal predictor. hypothesis was that CPRPC performs well prediction PPCs.The aim our study provide external validation resection primary tumours, before...
The experts have argued about the use of risk, injury, failure, loss and end-stage renal failure (RIFLE) criteria as a prognosis scoring system. We examined association between in-hospital mortality RIFLE criteria, discussed its accuracy factor.In this prospective study, we analysed data gathered from cohort 956 patients admitted in Spanish tertiary hospital January 1998 April 2006. Hazard ratios for mortality, survival curves within 60 days were calculated. Discrimination calibration model...
Karnofsky Performance Scale Index (KPS) is a measure of functional status that allows patients to be classified according their impairment. We aim assess if the prior KPS may predict risk death among with acute renal failure (ARF).A cohort 668 consecutive who had been admitted in an university-affiliated hospital between June 2000 and 2006, diagnosed ARF, were studied. Three hundred eighty-six ARF matched at least one RIFLE (Risk, Injury, Failure, Loss End stage) criteria on increased serum...
To determine risk factors for anesthesiologist intervention during routine cataract surgery performed with topical and intracameral anesthesia establish a regression model to identify high-risk patients.Department of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain.Prospective case series.After at an ambulatory surgical center, personnel completed questionnaire adverse medical events related intervention. A Poisson was used calculate the interventional risks. Bootstrapping...
Ephedrine is a direct/indirect vasoactive drug. In addition, it also possesses intrinsic local anesthetic properties, mainly due to its sodium-channel blockage. We investigated whether ephedrine demonstrates synergistic effect with bupivacaine and lidocaine when injected via spinal catheter into the space of rats.Spinal catheters were surgically placed in 47 rats (n = 8 per group; 7 excluded.) Bupivacaine, lidocaine, various concentrations constant volumes (60 μL) determine equipotency each...
Fundamento: El Síndrome de Distres respiratorio Agudo (SDRA) presenta una alta morbimortalidad. En su desarrollo intervienen mecanismos pro- y antiinflamatorios, cuyo balance depende en gran medida el transcurso la enfermedad.
 
 Observacion clinica resultados: Paciente afecto hepatopatía crónica por virus C, sin afectación funcional grave. Es sometido a tratamiento con Interferon Alfa, del cual un cuadro SDRA. A pesar las medidas tomadas, fallece los 37 días ingreso.
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