A5020426023- Essential Oils and Antimicrobial Activity
- Insect Pest Control Strategies
- Mosquito-borne diseases and control
- Psidium guajava Extracts and Applications
- vaccines and immunoinformatics approaches
- Insect and Pesticide Research
- HIV Research and Treatment
- Insect Utilization and Effects
- Computational Drug Discovery Methods
- Research on Leishmaniasis Studies
- Plant chemical constituents analysis
- Synthesis and Biological Evaluation
- Natural product bioactivities and synthesis
- Endodontics and Root Canal Treatments
- Bioactive Compounds and Antitumor Agents
- Medicinal Plant Research
- Phytochemistry and Biological Activities
- Nanocomposite Films for Food Packaging
- Oral microbiology and periodontitis research
- Traffic and Road Safety
- Monoclonal and Polyclonal Antibodies Research
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Reactions of Organic Compounds
- Latin American Urban Studies
Universidad del Valle de México
2023
Instituto Politécnico Nacional
2016-2023
Autonomous University of Chihuahua
2013-2023
Essential oils and their constituents are commonly known for antibacterial, antifungal antiparasitic activity, there also reports on the antimycobacterial properties, but more experimental data needed description of mechanism action or structural (and molecular) properties related to antimicrobial activity. Twenty-five essential were evaluated against Mycobacterium tuberculosis H37Rv bovis AN5 by Alamar Blue technique. Twenty compounds modeled using in silico techniques descriptor generation...
The biological activity of essential oils and their major components is well documented. Essential such as oregano cinnamon are known for effect against bacteria, fungi, even viruses. mechanism action proposed to be related membrane external cell structures, including walls. This study aimed evaluate the seven eight Gram-negative Gram-positive filamentous protozoans. antimicrobial was evaluated by determination Minimal Inhibitory Concentration Bacillus cereus, Staphylococcus aureus, Listeria...
The larvicidal activity of essential oils cinnamon (Cinnamomumverum J. Presl), Mexican lime (Citrusaurantifolia Swingle) cumin (Cuminumcyminum Linnaeus), clove (Syzygiumaromaticum (L.) Merr. & L.M.Perry), laurel (Laurusnobilis oregano (Lippiaberlandieri Schauer) and anise (Pimpinellaanisum Linnaeus)) their major components are tested against larvae pupae Culexquinquefasciatus Say. Third instar used for determination lethality mortality. Essential with more than 90% mortality after a...
Aedes aegypti is a vector for the arbovirus responsible yellow fever, Zika and Chikungunya virus. Essential oils their constituents are known larvicidal properties strong candidates mosquito control. This work aimed to develop quantitative structure-activity study molecular screening search design of new agents. Twenty-five monoterpenes with previously evaluated activity were built optimized using computational tools. QSAR models constructed through genetic algorithms from calculation...
In order to develop new larvicidal agents derived from phytochemicals, the activity of fifty molecules that are constituent essential oils was evaluated against Culex quinquefasciatus Say. Terpenes, terpenoids and phenylpropanoids were included in vitro evaluation, QSAR models using genetic algorithms built identify molecular structural properties biological interest. Further, obtain details on possible mechanism action, selected compounds submitted docking studies sterol carrier protein-2...
Origanum comprises several species, being the most common vulgare, a plant endemic of Europe, and Lippia graveolens or berlandieri found in North America. Aside from its potential economic benefits, essential oil oregano, regardless has wide range effects on bacteria, some them resistant to antibiotics general use, fungi, parasites. In Mexico there are more than 4,000 species medicinal plants, just northern state Chihuahua have been reports over 300 currently one Mexican oregano Schauer....
In this study Essential oils were used with cumin, cloves, cinnamon, laurel and anis to determine Minimum Inhibitory Concentration (MIC) against Mycobacterium tuberculosis strains. The MICs determined on M. H37Rv sensitive all five firstline antituberculosis drugs (streptomycin, isoniazid, rifampicin, ethambutol pirazinamide), two H37-Rv (CH-8 CH-15) isoniazid-resistant, (CH-07 CH-09) rifampicin-resistant, (CH-03 CH-06) streptomycin-resistant, (CH-09 CH-10) ethambutol-resistant using the...
Human immunodeficiency virus type-1 (HIV-1) has infected more than 40 million people around the world. HIV-1 treatment still several side effects, and development of a vaccine, which is another potential option for decreasing human infections, faced challenges. This work presents computational study that includes quantitative structure activity relationship(QSAR) using density functional theory(DFT) reported peptides to identify principal quantum mechanics descriptors related peptide...
Quinoxalines have shown a wide variety of biological activities including as antitumor agents. The aims this study were to evaluate the activity quinoxaline 1,4-di-N-oxide derivatives on K562 cells, establishment mechanism induced cell death, and construction predictive QSAR models.Sixteen esters quinoxaline-7-carboxylate evaluated for chronic myelogenous leukemia cells their IC50 values determined. death by most active molecule was assessed flow cytometry an in silico conducted optimize...
S. Andrade Ochoa*, K.F. Chacon Vargas*, J. Correa Basurto, L.M. Rodriguez Valdez, G.V. Nevarez Moorillon and L. E. Sanchez Torres** 1 ENCB-IPN. Prolongacion de Carpio y Plan Ayala s/n, Col. Casco Santo Tomas, Delegacion Miguel Hidalgo, C.P. 11340, Mexico, D.F. Mexico 2 ESM-IPN. San Luis Diaz Miron 3 FCQ-UACH. Campus Universitario #2 Circuito Universitario. 31125, Chihuahua, Chihuahua. * Both authors contributed equally to this work ** Corresponding author: email: luviasanchez@hotmail.com
The Human Immunodeficiency Virus (HIV-1) causes Acquired Syndrome (AIDS) and a high percentage of deaths. Therefore, it is necessary to design vaccines against HIV-1 for the prevention AIDS. Bioinformatic tools theoretical algorisms allow us understand structural proteins viruses develop based on immunogenic peptides (epitopes). In this work, we identified epitopes: P1, P2, P10, P27 P30 from gp120 protein HIV-1. These were administered intranasally alone or with cholera toxin (CT) BALB/c...
El presente trabajo tiene como objetivo evaluar la actividad antimicrobiana y las propiedades de inhibición formación biopelículas del sulfato cobre (Cu2SO4) en asociación con compuestos terpénicos sobre cepas L. acidophilus S. mutans. Para tal efecto, se determinó concentración mínima inhibitoria (CMI) utilizando resazurina indicador metabolismo celular. Los efectos determinaron por medio técnica tablero ajedrez biopelícula disminución conteo microbiano. resultados demuestran que el Cu2SO4...
El presente documento examina la relación entre los puentes peatonales de ciudad Chihuahua, México, y el número peatones atropellados en sus inmediaciones. análisis inició con evaluación caminabilidad entornos donde se ubican peatonales; posteriormente utilizaron sistemas información geográfica para geolocalización casos atropellamientos periodo 2015-2020 realizó un multivariante utilizando algoritmos genéticos. Los resultados obtenidos evidenciaron que 34,7% Chihuahua ocurre a 300 metros...
Fungal genera Alternaria and Fusarium include human plant pathogenic species. Several antifungals have been used for their control, but excessive use has contributed to resistance development in pathogens. An alternative searching developing new antifungal agents is using essential oils main components, which biological activities of interest medicine food production.To evaluate vitro silico the terpenoids against alternata oxysporum.The minimum inhibitory concentration fungicidal values 27...