This paper reports an efficient heterogeneous catalyst system based on the immobilization of Pd nanoparticles a silica–starch substrate (PNP–SSS). The PNP–SSS is found as highly effective recyclable in Heck and copper-free Sonogashira reactions. (SSS) can stabilize effectively so that it provide platform prevent aggregation their separation from surface. It also provides suitable catalytic sites for reactions aqueous media. are performed presence small amount this water green solvent. be...

A green and efficient one-pot process to achieve 5-aryl-pyrimido[4,5-b]quinoline-dione derivatives, using a three-component reaction involving anilines, aldehydes barbituric acids was developed. This protocol accomplished efficiently L-proline as catalyst in an aqueous medium give the corresponding products high yield. Also, 2-amino-4-arylquinoline-3-carbonitrile derivatives were obtained by replacing acid with malononitrile designed protocol. The catalytic activity of these reactions tested...

An efficient ruthenium-catalyzed acceptorless dehydrogenative coupling reaction of primary alcohols with 2-aminophenol for one-pot synthesis benzoxazoles is introduced. The phosphine-functionalized magnetic nanoparticles (PFMNPs; Fe3O4@SiO2@PPh2) as a recyclable phosphorus ligand in the presence Ru2Cl4(CO)6 was found to be an heterogeneous catalytic system promotion designed protocol. carried out efficiently variety substrates give corresponding products moderate good yields.

Abstract magnified image Silica‐bonded S ‐sulfonic acid (SBSSA) has been found to be an efficient catalyst for the synthesis of 1,8‐dioxo‐decahydroacridines and 1,8‐dioxo‐octahydroxanthenes in excellent yields. The former have synthesized from aromatic aldehydes, amines, 5,5‐dimethyl‐1,3‐cyclohexanedione, whereas latter this mixture without amines. method is easy access functionalized acridine xanthene derivatives. can reused. J. Heterocyclic Chem., (2010).

A metal–organic framework [MIL-101(Cr)] was used as an efficient heterogeneous catalyst in the synthesis of benzoazoles (benzimidazole, benzothiazole, and benzoxazole), quantitative conversion products were obtained under optimized reaction conditions. The could be simply extracted from mixture, providing clean synthetic methodology for benzoazoles. MIL-101(Cr) reused without a remarkable decrease its catalytic efficiency.

This study offers an example of using a silica–cyclodextrin (SCD) substrate for the capture metal nanoparticles to prepare novel nanocatalyst catalytic organic reactions in water as green solvent. Also, simple and efficient method size control palladium (PdNPs) their immobilization on SCD was introduced. These new catalyst systems were fully characterized some different techniques such XRD, TEM, SEM, TGA, ICP, XPS, FT-IR. The average immobilized PdNPs silica α-, β-, γ-CD substrates obtained...

Magnetic nanoparticles were functionalized with <sc>l</sc>-cysteine using a new and efficient method introduced as novel magnetically separable organocatalyst.

A novel heterogeneous Pd–catalyst system (Pd-MNPSS) was developed using immobilization of Pd species (PdII and Pd0) on starch-functionalized magnetic nanoparticles. For the synthesis Pd-MNPSS catalyst, first, nanoparticles (MNPs) were prepared coated with a silica layer (Fe3O4@SiO2) to increase their stability functionalization capability. The Fe3O4@SiO2 particles reacted thionyl chloride (SOCl2) generate chlorosilyl groups surface MNPs. Reaction starch chloro-functionalized MNPs leads...

Pyridinedicarboxamide (PDCA) ligands have been widely integrated into different polymer chemistries and provided promising self-healing properties in bulk upon adding specific metal ions. However, their application the development of synthetic hydrogels is limited due to lack clear kinetics thermodynamic data. To fill this gap, we study dynamics formed by condensation linear poly(ethylene glycol) (PEG) precursors PDCA ligand, followed complexation with ions at various pH values. Rheological...

Abstract 2,4,6‐Trichloro‐1,3,5‐triazine (TCT) was used as an efficient and mild reagent for the direct nickel‐catalyzed amination of phenols. This can promote phenols via activation phenolic CO bond. In this simple protocol, in situ generated aryl electrophile (Ar‐O‐TCT) reacts with desired amine to produce corresponding arylamine presence a nickel catalyst. strategy is general variety substrates give related arylamines moderate good yields. method also applied synthesis primary aromatic...

A new method for C-O bond activation of phenolic compounds has been achieved using 2,4,6-trichloro-1,3,5-triazine to utilize in one-pot Ni-catalyzed deoxygenation and reductive homocoupling reactions. With this simple method, were converted their corresponding arenes or biaryl under mild conditions. The introduced methodology a broad scope demonstrates good functional group compatibility.

A novel Pd−NHC functionalized metal–organic framework (MOF) based on MIL‐101(Cr) was synthesized and used as an efficient heterogeneous catalyst in the C‐C bond formation reactions. Using this Pd system, Suzuki−Miyaura coupling reaction accomplished well water, products were obtained good to excellent yields short time. The Pd−NHC−MIL‐101(Cr) characterized using some different techniques, including Fourier transform‐infrared, X‐ray diffraction, scanning electron microscopy, energy‐dispersive...

ConspectusFinding efficient synthetic methods for the asymmetric synthesis of complex molecules has always been interest to organic chemists. Creating and controlling stereochemistry stereogenic centers bearing branched allylic moieties in using a catalytic process is an attractive successful method several natural products medicinally important compounds. Remarkable progress toward their achieved via transition-metal catalysis, especially case substitution C-H oxidation chemistry. However,...

A simple, clean, and highly efficient solvent-free procedure for the preparation of bis(1H-indol-3-yl)methanes is described from reaction carbonyl compounds (aldehydes ketones) with 1H-indole in presence trityl chloride as a catalyst. The proceeds rapidly high yields at room temperature neutral medium. proposed mechanism suggested based upon former reactions calculated results.

A highly efficient and easily recyclable magnetic nanoparticle supported palladium catalyst was developed applied in the Heck Sonogashira reactions order to show its catalytic applicability Pd-catalyzed C–C coupling protocols.

A new class of α-aminophosphonate derivatives incorporating benzimidazole, theophylline and adenine nucleobases were synthesized in a three-step process the anticancer activities selected ligands evaluated.

In this study, a multicomponent reaction involving carbohydrates, β-dicarbonyl compounds, and malononitrile was disclosed to synthesize new class of polyhydroxy compounds incorporating pyrano[2,3-d]pyrimidine, pyrido[2,3-d]pyrimidine chromene heterocycles under mild conditions. For the synthesis glucose, galactose, arabinose, maltose, lactose were used as aldehyde component in with barbituric acid produce pyrano[2,3-d]pyrimidine derivatives. By use 1,3-cyclohexanedione instead acid,...

The needs for diverse inhibitors of α-glucosidase (α-Gls) encouraged us to synthesize five different poly-hydroxy functionalized pyrimidine-fused heterocyclic (PHPFH) molecules, having either aliphatic or aromatic side chains (C1–C5) and their inhibitory activities were examined spectroscopically against yeast mouse intestinal α-Gls. results revealed that substitution the synthetic compounds has significant impact on properties. Moreover C3 with substituted moiety as...

This paper reports the preparation, characterization and catalytic application of a novel, magnetically separable catalyst consisting tungstic acid supported on silica coated magnetic nanoparticles.