- Trauma and Emergency Care Studies
- Sepsis Diagnosis and Treatment
- Trauma Management and Diagnosis
- Immune Response and Inflammation
- Traumatic Brain Injury and Neurovascular Disturbances
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Abdominal Trauma and Injuries
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Pelvic and Acetabular Injuries
- Spinal Fractures and Fixation Techniques
- Neonatal Respiratory Health Research
- Emergency and Acute Care Studies
- Hip and Femur Fractures
- Palliative Care and End-of-Life Issues
- Injury Epidemiology and Prevention
- Abdominal Surgery and Complications
- Bone fractures and treatments
- Mesenchymal stem cell research
- Blood transfusion and management
- Hernia repair and management
- Hematological disorders and diagnostics
- Pleural and Pulmonary Diseases
- Traffic and Road Safety
Rutgers, The State University of New Jersey
2015-2024
Rutgers New Jersey Medical School
2015-2024
University of Maryland Medical Center
2023
University of Maryland, Baltimore
2015-2023
Memorial Hospital
2023
The University of Texas Southwestern Medical Center
2023
Cornell University
2023
ECI Biotech (United States)
2023
University Hospital, Newark
2008-2022
Creative Commons
2022
Geriatric trauma patients have a worse outcome than the young with comparable injuries. The contribution of traumatic brain injury (TBI) to this increased mortality is unknown and has been confounded by presence other purpose study was investigate role age in early from isolated TBI.This retrospective analysis all adult TBI (Abbreviated Injury Scale score > or = 3) admitted during 5-year period two Level I centers. Mortality, Glasgow Outcome at discharge, therapy, complications were compared...
Objective: Elderly patients (aged 60 years and older) have been demonstrated to an increased mortality after isolated traumatic brain injury (TBI); however, the prognosis of those surviving their hospitalization is unknown. We hypothesized that elderly would also decreased functional outcome, this study examined outcome with TBI at discharge 6 months posthospitalization. Methods: This was a multicenter prospective all moderate severe defined as Head Abbreviated Injury Scale score 3 in any...
Angiographic embolization (AE) is a safe and effective method for controlling hemorrhage in both blunt penetrating liver injuries. Improved survival after hepatic injuries has been documented using multimodality approach; however, patients still have significant long-term morbidity. This study examines further the role of AE outcomes its use.The medical records 37 consecutive admitted from 1995 to 2002 Level I trauma center who underwent angiography with intent embolize were reviewed....
Objectives Hospitalization for observation is the current standard of practice patients who have sustained blunt abdominal trauma and do not require emergent operation, despite having undergone diagnostic studies that exclude presence an intra-abdominal injury. The reasons this are multifactorial include perceived false-negative rate all tests, belief hospitalization will allow prompt diagnosis occult injuries, medicolegal considerations about risk early discharge. focus study was to...
Background: Ten percent to 20% of trauma patients admitted the intensive care unit (ICU) will die from their injuries. Providing appropriate end-of-life in this setting is difficult and often late patients' course. Patients are young, prognosis uncertain, conflict common around goals care. We hypothesized that early, structured communication ICU would improve practice. Methods: Prospective, observational, prepost study on consecutive before after a palliative intervention was integrated into...
Objective Concern for thoracolumbar spine (TLS) injuries after major trauma mandates immobilization pending radiographic evaluation. Current protocols use standard posteroanterior and lateral radiographs of the (XR/TLS), but many patients also undergo abdominal or thoracic computed tomographic (CT) scanning. We sought to evaluate whether helical truncal CT scanning performed visceral images as well dedicated XR/TLS. Methods prospectively studied 222 consecutive sustaining high-risk requiring...
• Monocyte HLA-DR antigen expression and mitogen-stimulated interferon gamma production were measured sequentially on days 1, 3, 7,14, 21 after admission in 20 multiply injured patients (mean Injury Severity Score, 33). Ten recovered uneventfully ten developed a major infection, three of whom died. Trauma resulted immediate profound depression both monocyte compared with controls. Interferon remained below control levels for all which it was patients. In uninfected patients, began to recover...
The number of rib fractures has been reported to correlate with mortality after blunt chest trauma. These reports, however, predate routine truncal helical computed tomographic (CT) scanning and their conclusions are based on data derived from plain radiographs (CXR). CT scan provides better anatomic definition injuries than CXR, we hypothesized evaluation fracture patterns would provide a prediction respiratory failure injury the initial CXR.The charts all patients 16 years or older one...
Background: Since the promulgation of emergency department (ED) thoracotomy >40 years ago, there has been an ongoing search to define when this heroic resuscitative effort is futile. In era health care reform, generation accurate data imperative for developing patient guidelines. The purpose prospective multicenter study was identify injury patterns and physiologic profiles at ED arrival that are compatible with survival. Methods: Eighteen institutions representing Western Trauma Association...
Trauma centers successfully save lives of severely injured patients who would have formerly died. However, survivors often multiple complications and morbidities associated with prolonged intensive care unit (ICU) stays. Because the reintegration into society to lead an active a productive life is ultimate goal trauma center care, we questioned whether our "success" may condemn these fate worse than death?Charts on all > or =18 years ICU stay =10 days, discharged alive between June 1, 2002,...
BACKGROUND Two decades ago, hypotensive trauma patients requiring emergent laparotomy had a 40% mortality. In the interim, multiple interventions to decrease hemorrhage-related mortality have been implemented but few any documented evidence of change in outcomes for laparotomy. The purpose this study was determine current rates undergoing METHODS A retrospective cohort all adult, laparotomies performed 2012 2013 at 12 Level I centers reviewed. Emergent defined as emergency department (ED)...
This is a recommended algorithm of the Western Trauma Association for acute management penetrating chest injury. Because paucity recent prospective randomized trials on evaluation and injury, current algorithms recommendations are based available published cohort, observational retrospective studies, expert opinion members. The two should be reviewed in following sequence: Figure 1 damage-control strategies unstable patient 2 definitive repair stable patient. will discuss techniques; focus...
Nicotinamide adenine dinucleotide (NAD) levels decline with aging and age-related in NAD has been postulated to contribute diseases.
Hematopoietic failure has been observed in experimental animals following shock and injury. In humans, bone marrow dysfunction the red cell component characterized by a persistent anemia, low reticulocyte counts, need for repeated transfusions despite adequate iron stores. While quantitative defect white blood count not noted, an alteration function manifesting as increased susceptibility to infection is well established. Since etiology of this anemia remains unknown rarely studied injury,...
Objective To determine the negative predictive value of cranial computed tomography (CT) scanning in a prospective series patients and whether hospital admission for observation is mandatory after diagnostic evaluation minimal head injury (MHI). Summary Background Data Hospital current standard practice who have sustained MHI, despite having undergone studies that exclude presence an intracranial injury. The reasons this are multifactorial include perceived false-negative rate all tests,...
Recent data have suggested that patients with both a normal cranial CT scan and neurologic examination following minimal head injury (MHI) no risk of deterioration. This study prospectively examined the safety discharging from emergency department (ED) after MHI whether or not there was responsible observer at home. defined as history loss consciousness (LOC), Glasgow Coma Scale (GCS) score 14 15, focal findings. In 4-month period 111 were evaluated. Fifteen (14%) had which revealed an...
Background: Age has been shown to be a primary determinant of survival following isolated traumatic brain injury (TBI). We have previously reported that patients ≥65 years who survived mild TBI decreased functional outcome at 6 months compared with younger patients. The purpose this study was further investigate the effect age on 1 year in all surviving TBI. Methods: Western Trauma Association multicenter prospective included sustaining defined as Abbreviated Injury Scale score for Head ≥ 3...
To test the hypothesis that comparably injured women, especially those in hormonally active age groups, would manifest a better preserved hemodynamic response and tissue perfusion after major trauma than do men.The notion premenopausal women are more resistant men to shock has been shown numerous preclinical models. However, human studies on effects of gender outcome shock-trauma less clear, none examined effect immediate postinjury trauma.Prospective series all patients at Level I center...
Patients with minimal head injury (MHI) and intracranial bleed (ICB) detected on cranial computed tomography (CT) scan routinely undergo a repeat CT within 24 hours after to assess for progression of injuries. While this is clearly beneficial in patients deteriorating neurologic status, it questionable value normal examination. The goal study was prospectively the MHI an ICB who have examination.A prospective analysis all adult admitted Level I trauma center blunt causing (defined as loss...
Perceptions of violence are too often driven by individual sensational events, yet "routine" gunshot wound (GSW) injuries largely underreported. Previous studies have mostly focused on fatal GSW. To illuminate this public health problem, we studied the care burden interpersonal GSW at a Level I trauma center.Retrospective analysis (excluding self and law enforcement) treated from January 2000 to December 2011. Data collected included body regions injured, number wounds per patient,...
This document provides guidance for trauma and acute care surgeons surrounding the placement, management removal of chest tubes during COVID-19 pandemic.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus rapidly and likely permanently changed the delivery of health care through hospitals across country. These changes were implemented out necessity during surge COVID-19 patients but have short- long-term unintended consequences to our trauma centers. Severe injury does not respect constraints placed on healthcare pandemic. Trauma was will continue be a major policy issue leading cause death disability. potential for...