- Algal biology and biofuel production
- Microbial Metabolic Engineering and Bioproduction
- Biochemical and biochemical processes
- Enzyme Catalysis and Immobilization
- Plant Disease Resistance and Genetics
- Marine and coastal ecosystems
- Plant-Microbe Interactions and Immunity
- Metabolomics and Mass Spectrometry Studies
- Fungal Biology and Applications
- Plant biochemistry and biosynthesis
- Plant Gene Expression Analysis
- Microbial Community Ecology and Physiology
- Phytochemicals and Antioxidant Activities
- Plant Reproductive Biology
- Advanced Synthetic Organic Chemistry
- Marine Sponges and Natural Products
- Cannabis and Cannabinoid Research
- Mycorrhizal Fungi and Plant Interactions
- Plant tissue culture and regeneration
- Essential Oils and Antimicrobial Activity
- Biochemical Acid Research Studies
- Agronomic Practices and Intercropping Systems
- Lipid metabolism and biosynthesis
- Polyamine Metabolism and Applications
- Chemical synthesis and alkaloids
Université du Québec à Trois-Rivières
2019-2025
Université de Sherbrooke
2019
Marine water diatom Phaeodactylum tricornutum is a photosynthetic organism that known to respond the changing light environment and adapt different temperatures prevent photoinhibition maintain its metabolic functions. The objective of present study was test whether shift variations in growth phases impact lipid metabolism P. tricornutum. Thus, we investigated R exposure find most effective condition. results showed substituting white (W) by red (R) under autotrophic conditions, condition...
The increasing demand for novel natural compounds has prompted the exploration of innovative approaches in bioengineering. This study investigates bioengineering potential marine diatom Phaeodactylum tricornutum through introduction cannabis genes, specifically, tetraketide synthase (TKS), and olivetolic acid cyclase (OAC), production cannabinoid precursor, (OA). P. is a promising biotechnological platform due to its fast growth rate, amenability genetic manipulation, ability produce...
Pharmaceutical safety is an increasing global priority, particularly as the demand for therapeutic compounds rises alongside population growth. Phytocannabinoids, a class of bioactive polyketide molecules derived from plants, have garnered significant attention due to their interaction with human endocannabinoid system, offering potential benefits managing range symptoms and conditions. Traditional extraction cannabis plants poses regulatory, environmental, yield-related challenges....
Canada has made significant contributions to the field of plant biochemistry, with numerous researchers actively focusing on elucidating biosynthetic pathways specialized metabolites and producing these compounds in heterologous systems, such as bacteria, yeast, or other species. The review aims highlight strengths Canadian research this domain over last three decades. It will describe advances pathway elucidation, enzyme characterization, production enzymes particularly areas alkaloids,...
Abstract Background Thaxtomin A (TA) is a natural cellulose biosynthesis inhibitor (CBI) synthesized by the potato common scab-causing pathogen Streptomyces scabies . Inhibition of synthesis TA compromises cell wall organization and integrity, leading to induction an atypical program death (PCD). These processes may facilitate S. entry into plant tissues. To study mechanisms that regulate in response inhibition synthesis, we used Arabidopsis thaliana suspension cultures treated with two...
Light regulates important metabolic processes in microalgal cells, which can further impact the metabolism and accumulation of biomolecules such as lipids, carbohydrates, proteins. Different characteristics light have been studied on various strains model diatom Phaeodactylum tricornutum, but not transconjugant cells information wild-type is still limited. Therefore, we different spectral quality, intensity shift growth, composition lipids fatty acids P. tricornutum to provide a...
Chaga (Inonotus obliquus) is a medicinal fungus used in traditional medicine of Native American and North Eurasian cultures. Several studies have demonstrated the properties chaga's bioactive molecules. For example, several terpenoids (e.g., betulin, betulinic acid inotodiol) isolated from I. obliquus cells proven effectiveness treating different types tumor cells. However, molecular mechanisms regulation underlying biosynthesis chaga remain unknown. In this study, we report on optimization...
With a world growing in population and nutritional needs, diatoms are considered nowadays as microalgae of very important potential, thus they exploited several fields such ecology, aquaculture, molecular farming, pharma nutraceuticals. These coveted characterized by their diversity, high division rates, complex life cycle, likewise silicified cell walls named frustules. Thus, have been used for over century after proving an efficient production molecules including Triacylglycerols (TAGs),...
Thaxtomin A (TA) is a cellulose biosynthesis inhibitor synthesized by the soil actinobacterium Streptomyces scabies, which main causal agent of potato common scab. TA essential for induction scab lesions on tubers. When added to Arabidopsis thaliana cell cultures, induces an atypical programmed death (PCD). Although production reactive oxygen species (ROS) often correlates with PCD, we observed decrease in ROS levels following treatment. We show that this accumulation TA-treated cells not...
Armillaria sinapina, a fungal pathogen of primary timber species North American forests, causes white root rot disease that ultimately kills the trees. A more detailed understanding molecular mechanisms underlying this illness will support future developments on resistance and management, as well in decomposition cellulosic material for further use. In study, RNA-Seq technology was used to compare transcriptome profiles A. sinapina culture grown yeast malt broth medium supplemented or not...
Vanillin, an aromatic aldehyde, is one of the most popular flavors worldwide, extensively used in food, cosmetics, pharmaceutical, and agrochemical industries. Despite its widespread use, less than 1% total vanillin production natural, with majority being synthesized chemically. While chemical synthesis can help to meet growing demand for vanillin, a strong market trend has rapidly developed products created from natural ingredients, including vanillin. Given labor-intensive process...