- Plant Stress Responses and Tolerance
- Psoriasis: Treatment and Pathogenesis
- Plant responses to elevated CO2
- Rheumatoid Arthritis Research and Therapies
- Autoimmune Bullous Skin Diseases
- Systemic Lupus Erythematosus Research
- Light effects on plants
- Plant responses to water stress
- Photosynthetic Processes and Mechanisms
- Spondyloarthritis Studies and Treatments
University of Lübeck
2020-2021
University Hospital Schleswig-Holstein
2020-2021
Cyprus University of Technology
2014-2020
Recent reports have uncovered the multifunctional role of melatonin in plant physiological responses under optimal and suboptimal environmental conditions. In this study, we explored whether pretreatment could provoke priming effects alfalfa (Medicago sativa L.) plants subsequently exposed to prolonged drought stress (7 days), by withholding watering. Results revealed that rhizospheric application (10 μmol L-1 ) remarkably enhanced tolerance plants, as evidenced observed tolerant phenotype,...
Land plants are continuously exposed to multiple abiotic stress factors like drought, heat, and salinity. Nitric oxide (NO) hydrogen sulfide (H2S) two well-examined signaling molecules that act as priming agents, regulating the response of stressful conditions. Several chemical donors exist provide with NO H2S separately. NOSH is a remarkable novel donor it can donate simultaneously plants, while NOSH-aspirin additionally provides pharmaceutical molecule acetylsalicylic acid. The current...
Drug-induced lupus erythematosus is a rare adverse event of biological treatment, mainly observed with tumor necrosis factor–α antagonists and also known as lupus-like syndrome. Recently, it was described interleukin (IL) 17 inhibition. Here, we report the case 39-year-old man onset cutaneous discoid during subcutaneous administration IL-17A inhibitor secukinumab, which initiated for treatment chronic plaque psoriasis.
To investigate the drug survival of secukinumab (SEC), ustekinumab (UST), and certolizumab pegol (CZP) in real-world conditions to identify predictors reasons for treatment discontinuation.We performed a 2-year retrospective single-center analysis 110 courses 98 patients with moderate severe plaque-type psoriasis and/or psoriatic arthritis (SEC n = 68; UST 29; CZP 13). Drug was examined using Kaplan-Meier influence demographic factors on Cox regression analysis.Drug rates at 12 18 months...