A5109840982- Breast Cancer Treatment Studies
- Cell death mechanisms and regulation
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
- Cutaneous Melanoma Detection and Management
- Cancer and Skin Lesions
- Cancer Diagnosis and Treatment
- Nonmelanoma Skin Cancer Studies
- Cancer Risks and Factors
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Cancer-related Molecular Pathways
- Reconstructive Surgery and Microvascular Techniques
- Acute Myeloid Leukemia Research
- Anorectal Disease Treatments and Outcomes
- Global Cancer Incidence and Screening
- Diverticular Disease and Complications
- RNA Interference and Gene Delivery
- NF-κB Signaling Pathways
- Multiple and Secondary Primary Cancers
- Protease and Inhibitor Mechanisms
- Oral and Maxillofacial Pathology
- Body Image and Dysmorphia Studies
- Colorectal Cancer Surgical Treatments
- Melanoma and MAPK Pathways
Polish Mother’s Memorial Hospital Research Institute
2020-2025
Copernicus Memorial Hospital
2010-2019
Medical University of Lodz
2005-2015
Society of Surgical Oncology
2008
To establish risk factors for onset and progression of endometrioid endometrial cancer still remains the aim scientists. The study was to determine disease-free survival (DFS) overall (OS) in women with cancer.A retrospective review 142 patients after surgery treated adjuvant radiotherapy and/or chemotherapy Regional Cancer Centre Lodz between 2002 2004 performed. Clinical pathological data were correlated clinical outcome survival.In 3 (2.1%) diagnosed during treatment. In 23 (16.7%)...
Background: Sentinel lymph node biopsy (SLNB) is the primary procedure for nodal assessment in breast cancer patients. Radioisotopes (RIs) are considered gold-standard tool. The ferromagnetic technique (superparamagnetic iron oxide—SPIO) a non-isotope alternative SLNB method. This study compares efficacy of SPIO and RI across two independent centres. Methods: A total 406 patients, who underwent between January 2021 December 2022, were analysed (SPIO—223 RI—183 patients). Statistical tests,...
Melanoma of unknown primary site (MUP) is not a completely understood entity with nodal metastases as the most common first clinical manifestation. The aim this multicentric study was to assess frequency and type oncogenic BRAF/NRAS/KIT mutations in MUP clinically detected relation clinicopathologic features outcome. We analyzed series 103 patients (period: 1992–2010) after therapeutic lymphadenectomy (LND): 40 axillary, 47 groin, 16 cervical, none treated BRAF inhibitors. performed...
Smac/DIABLO protein promotes caspase-dependent apoptosis by inhibition of inhibitor (IAP) family members. The role in breast cancer has not been yet established. Therefore, the aim study was to assess expression this tumor cells from patients. analyzed 62 patients flow cytometry. obtained results were compared with benign tissue, which served as control (11 fibroadenoma). Expression caspase-3 proteins also evaluated. correlated clinical and pathological data. Although found all examined...
Inhibitor of apoptosis (IAP) family proteins is involved in mechanisms resistance to various cancer cells. The aim this study was assess the expression selected IAP such as XIAP, cIAP-1, cIAP-2 and survivin breast patients evaluates their relationship with prognostic predictive factors impact overall survival (OS) progression free (PFS). conducted use tissue samples prospectively collected from 92 previously untreated female patients. control encompassed 10 fibroadenoma assessed using flow...
Analysis of the clinical course patients with postirradiation rectovaginal fistula after fecal diversion. The studied group included 17 women who underwent diversion as a sole mode treatment, between January 1987 and December 2002, in our department. All were subjected to radiotherapy due cancer uterine cervix, administered 5-107 months before appearance (mean, 22.9 months). In 3 (18%), spontaneous closure was observed 5, 6, 9 months, respectively, from Closure confirmed by endoscopy. Length...
Background and Objectives The goal of this study was to measure absorbed doses radiation the hands medical staff performing sentinel node biopsy (SNB) in skin melanoma patients. Methods conducted from January 2004 May 2004, during SNBs (lymphoscintigraphy—99mTc on albumin carrier, surgery after 24 hr; blue dye; intraoperative detection gamma radiation) 22 During lymphoscintigraphy surgical procedures, 57 highly sensitive thermoluminescent dosimeters (TLDs) were placed different parts staff....
Bax protein, the proapoptotic member of Bcl-2 protein family, plays key role in apoptosis pathway. THE AIM OF STUDY was to assess expression breast cancer cells.Sixty-two patients were included study. The control group encompassed 11 fibroadenoma patients. Single cells isolated from defrosted samples and prepared for flow cytometry measurement.Median study 7.9% (range: 0-49.4%) significantly lower than (median 15.8%; range 4.9-30.9%; p=0.034). Expression correlated with p53 caspase-3...
The inhibitor of apoptosis protein (IAP) family acts as an pathways. potential prognostic value the expression selected IAP members, XIAP, cIAP-1, cIAP-2 and survivin protein, was evaluated with regard to treatment response survival 56 newly diagnosed adult patients acute myeloid leukemia (AML). presence these members influenced achievement a complete (CR). In addition, overall (OS) by low in univariate multivariate analysis (p = 0.014 p 0.013, respectively). A strong correlation observed...
This text is based on the recommendations accepted by 4th Hungarian Consensus Conference Breast Cancer, modified basis of international consultation and conference within frames Central-Eastern European Academy Oncology. The cover non-operative, intraoperative postoperative diagnostics, determination prognostic predictive markers content cytology histology reports. Furthermore, they address some specific issues such as current status multigene molecular markers, role pathologists in clinical...
There are very few reports concerning the presence of malignant cystosarcoma phyllodes (CSP) in breasts pregnant women. In hereby described case, a 28-year-old woman presented our department with huge (18 x 11 8 cm) tumor left breast, 2 weeks after labor. The patient discovered 34th week pregnancy, 6 before Histopatholgic examination excised revealed CSP tumor. Simple mastectomy was proposed to as best treatment modality. However, refused. She underwent excision bed (2-cm tumor-free margin...
TRAIL protein may serve as an escape mechanism for cancer cells from the immune response. The aim of study was to assess whether presence correlates with unfavourable prognostic factors in breast carcinoma.The group composed patients treated surgically Department Surgical Oncology, Medical University Lodz, Poland, January December 2003. Inclusion criteria were fulfilled by 117 women. immunohistochemical expression performed 118 carcinomas diagnosed group. correlated other variables: tumour...
We present a unique case of carcinoma diagnosed in port-site, two years after uncomplicated laparoscopic cholecystectomy for benign cholecystitis. Analysis morphology and cytokeratin profile (CK19+ CK20+/-) resected port-site tumor allows us to establish the diagnosis tubular with probable cholangiogenic origin. The primary was not archival gallbladder tissue, despite repeated histological examination. No other identified during follow-up. Patient history histological/immunohistochemical...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Pluta P, Jesionek-Kupnicka D, Kubicka-Wołkowska J, et al. SMAC protein expression as a potent favorable prognostic factor in locally advanced breast cancer. Polish Journal of Pathology. 2018;69(1):33-41. doi:10.5114/pjp.2018.75334. APA Pluta, P., Jesionek-Kupnicka, D., Kubicka-Wołkowska, J., A., Brzozowski, K., & Potemski, P. (2018). Pathology, 69(1), 33-41. https://doi.org/10.5114/pjp.2018.75334 Chicago Piotr,...