A5082620563- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Gastrointestinal disorders and treatments
- Epigenetics and DNA Methylation
- Pediatric Hepatobiliary Diseases and Treatments
- Biliary and Gastrointestinal Fistulas
- Esophageal and GI Pathology
- Organ Transplantation Techniques and Outcomes
- Congenital Anomalies and Fetal Surgery
- Cancer, Hypoxia, and Metabolism
- Anatomy and Medical Technology
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Vascular Malformations and Hemangiomas
- HIV-related health complications and treatments
- Hemostasis and retained surgical items
- Cancer, Lipids, and Metabolism
- IgG4-Related and Inflammatory Diseases
- Appendicitis Diagnosis and Management
- Vascular Anomalies and Treatments
- Medical Case Reports and Studies
- Renal cell carcinoma treatment
- Tuberous Sclerosis Complex Research
Apollo Hospitals
2023
Medical College and Hospital, Kolkata
2010-2020
Institute of Post Graduate Medical Education and Research
2010-2017
All India Institute of Medical Sciences Jodhpur
2017
College of Medicine & Sagore Dutta Hospital
2016
R. G. Kar Medical College and Hospital
2011-2014
Bose (United States)
2009
All India Institute of Medical Sciences
2006
Pancreatic cancer (PanCa) is one of the most lethal cancers (survival ~ 12%). As conventional therapeutic interventions are mostly futile, a deep understanding disease pathophysiology an urgent need. Ion channels, located on cell membrane, contribute significantly to hallmarks, through dysregulation various ion translocation; however, fundamental mechanisms remain uncertain. To identify these oncochannels in Indian cohort PanCa, we utilized 450 K data, published our previous study, and...
Abstract Background Pancreatic Ductal Adenocarcinoma (PDAC) is a cancer of the exocrine pancreas and 5-year survival rates remain constant at 7%. Along with PDAC, Periampullary (PAC) accounts for 0.5–2% all gastrointestinal malignancies. Genomic observations were well concluded PDAC PACs in western countries but no reports are available from India till now. Methods Targeted Next Generation Sequencing performed 8 (5 3 PAC) tumour normal pairs, using panel 412 related genes. Primary findings...
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is one of the leading cancers worldwide and has a poor survival, with 5-year survival rate only 8.5%. In this study we investigated altered DNA methylation associated PDAC severity prognosis. Methods Methylome data, generated using 450 K bead array, was compared between paired normal samples in TCGA cohort (n = 9) our Indian 7). The total Cohort 75) split into 1 7), 2 22), 3 26) 4 20).Validation differential (6 selected CpG loci)...
Nonosseous or soft tissue Ewing's sarcoma is a rare form of sarcoma/primitive neuroectodermal tumour that seldom affects the head and neck region.Involvement nose paranasal sinuses extremely uncommon, with only eight such patients being reported to date, mostly affecting adolescents young adults.To our knowledge, this study first comprehensive report primary involving in an elderly patient who successfully completed treatment.We herein discuss pathogenesis, management factors prognosis group...
There is paucity of evidence regarding the role drain in laparoscopic cholecystectomy (LC) acute calculous cholecystitis (ACC), and surgeons have placed drains based on their experiences, not evidence-based guidelines. This study aims to assess value LC for ACC a randomised controlled prospective study.All patients with mild moderate undergoing were assessed. Preoperatively, choledocholithiasis, Mirizzi syndrome biliary stent excluded. Intraoperatively or postoperatively, complications,...
A 53 year man presented with pain right upper quadrant for seven months. On evaluation he was found to have a large adrenal myelolipoma. Laparoscopically by transperitoneal flank approach this removed. Postoperative recovery uneventful. Operative specimen's histopathological examination confirmed the diagnosis of
Simultaneous occurrence of pancreatic and hepatic mucinous cystic neoplasms is very rarely reported in the literature. We present a case with extensive fatty component tumour arising from head pancreas attaining huge size before being treated by Whipple's pancreatoduodenectomy subsequently right hepatectomy for tumour.
Abstract Background The clinico-surgical implication and successful management of a rare case factor five (V) deficiency with portal hypertension hypersplenism due to idiopathic extra-hepatic venous obstruction is presented. Case presentation A 16-year old boy had gastro-esophageal variceal bleeding, splenomegaly hypersplenism. During preoperative workup prolonged prothrombin time activated partial thromboplastin were detected, which on further evaluation turned out be V deficiency. Proximal...
Background: Laparoscopic cholecystectomy is considered "gold standard" for the treatment of gallstone disease.In spite increasing number laparoscopic cholecystectomies being performed as day care surgery in West, surgeons developing countries are reluctant to adopt this trend probably due inadequate resources and infrastructure which they consider a hindrance safe discharge.Our study aims assess feasibility cholecystectomies.Materials methods: This prospective observational study.All...