A5074799405- Protein Structure and Dynamics
- Electrohydrodynamics and Fluid Dynamics
- Radioactive element chemistry and processing
- Mass Spectrometry Techniques and Applications
- Polyamine Metabolism and Applications
- Enzyme Structure and Function
- Gold and Silver Nanoparticles Synthesis and Applications
University of California, San Diego
2019-2021
Significance Acyl carrier proteins (ACPs) are involved in primary and secondary metabolic pathways, including the ubiquitous fatty acid biosynthesis, required for all domains of life. This single protein must deliver pathway intermediates to appropriate enzyme, distinguishing between a myriad possible intermediate-enzyme combinations. The intermediate is delivered active site enzymes through large conformational change termed “chain flipping.” Whether chain flipping stochastic or regulated...
Lipases, as well other enzymes, are present and active within the sea surface microlayer (SSML). Upon bubble bursting, lipases partition into spray aerosol (SSA) along with surface-active molecules such lipids. Lipases likely to be embedded in lipid monolayer at SSA thus have potential influence interfacial structure chemistry. Elucidating of interfaces how this is altered upon interaction a protein system like lipase interest, given importance aerosols interact sunlight, cloud formation,...