A5059683141- Cardiovascular Effects of Exercise
- Sports injuries and prevention
- Traumatic Brain Injury Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Health Systems, Economic Evaluations, Quality of Life
- Metabolism, Diabetes, and Cancer
- Artificial Intelligence in Healthcare
- Muscle metabolism and nutrition
- Cardiovascular and exercise physiology
- Meta-analysis and systematic reviews
- COVID-19 and healthcare impacts
- Diabetes Treatment and Management
- Atrial Fibrillation Management and Outcomes
- Cardiac Imaging and Diagnostics
- Potassium and Related Disorders
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
Karolinska Institutet
2022-2025
Football (soccer) players might be at increased risk of neurodegenerative disease, which has led to questions regarding the safety sport and recent measures introduced by football associations reduce heading ball. We aimed assess disease among male in Swedish top division Allsvenskan, compared with matched controls.In this cohort study, we identified all (amateurs professionals) who had played least one game Allsvenskan from Aug 1, 1924 Dec 31, 2019 excluded whose personal identity number...
The aim of the ARC-HBR (Academic Research Consortium for High Bleeding Risk) and PRECISE-DAPT (Predicting Complications in Patients Undergoing Stent Implantation Subsequent Dual Antiplatelet Therapy) score definitions high bleeding risk is to identify patients who would benefit from shorter or less intensive antiplatelet therapy after coronary stenting. this study was assess performance routine clinical practice. Using nationwide registers, all Stockholm, Sweden, were discharged stenting...
Abstract Aims To assess treatment eligibility for, and received with, sodium–glucose co-transporter 2 inhibitors (SGLT2) glucagon-like peptide-1 (GLP-1) receptor agonists according to the 2019 American Diabetes Association (ADA)/European for Study of (EASD) consensus report European Society Cardiology (ESC) guidelines in a nationwide sample patients with type diabetes. Methods results Both sets included indications heart failure, chronic kidney disease, atherosclerotic cardiovascular disease...
To assess whether male elite football players are at increased risk of alcohol related disorders compared with men from the general population, and such an would vary on basis calendar year first playing season in top tier competition, age, career length, goal scoring abilities.Nationwide cohort study.Sweden, 1924-2020.6007 who had played Swedish division, Allsvenskan, 1924 to 2019 56 168 population matched based age region residence.Primary outcome was (diagnoses recorded death...
Objective To assess whether male elite football players, during and after their active career, were at increased risk of depression anxiety-related disorders suicide, as compared with the general population. Methods We included players in Swedish top division 1924–2019 population (matched to based on age region residence) aged <65 years 1997. Using nationwide registers, we followed from first season (or date registered residency Sweden) or 1 January 1997, (captured through diagnoses...
Abstract Background The 2021 ESC Guidelines on Cardiovascular Disease (CVD) Prevention in Clinical Practice recommend using (lifetime) risk to guide preventive treatment intensification. Purpose Updating and systematically recalibrating the SMART-REACH lifetime prediction model for estimation of recurrent CVD patients with established atherosclerotic (ASCVD) various European international regions. Methods updated (i.e., SMART-REACH2) was derived data from 9,477 individuals between 40-90...
Abstract Background Guideline recommendations for the prevention of cardiovascular (CV) events in patients with coronary artery disease (CAD) are one-size-fits-all. Clinically identifiable phenotypes needing specific considerations might exist. Purpose To identify CAD based on clinical characteristics and their relationship risk new CV treatment benefits. Methods Unsupervised machine learning through latent class analysis (LCA) was performed included UCC-SMART cohort (n = 5,888) SWEDEHEART...
Background Early in the COVID-19 pandemic, numerous clinical trials were initiated. Although concerns raised regarding quality of trials, eventual research output yielded from remains unknown. The objective this study was to include all registered on ClinicalTrials.gov during first 6 months pandemic and assess if where their results had been reported, completion discontinuation rates, achieved enrolment changes made primary outcome after trial registration. Methods We included interventional...
Abstract Background Dual antiplatelet therapy (DAPT) after coronary stenting reduces the risk of recurrent ischemia but increases bleeding risk. The PRECISE-DAPT score was developed using data from clinical trials to identify individuals at high who may benefit shorter DAPT duration. Although use is recommended in guidelines, its applicability patients seen routine practice uncertain. Purpose To assess performance a population-based cohort undergoing stenting. Methods We calculated enrolled...