A5035375081- Pesticide Exposure and Toxicity
- Poisoning and overdose treatments
- Advanced biosensing and bioanalysis techniques
- Electrochemical Analysis and Applications
- Heavy Metal Exposure and Toxicity
- Electrochemical sensors and biosensors
- Effects and risks of endocrine disrupting chemicals
- Advanced Nanomaterials in Catalysis
- Mercury impact and mitigation studies
- Adipose Tissue and Metabolism
- Vitamin C and Antioxidants Research
- Circadian rhythm and melatonin
- Carcinogens and Genotoxicity Assessment
- Cholinesterase and Neurodegenerative Diseases
- Genomics, phytochemicals, and oxidative stress
- Neuroscience and Neuropharmacology Research
- Aluminum toxicity and tolerance in plants and animals
- Toxic Organic Pollutants Impact
- Biochemical effects in animals
- Neuroinflammation and Neurodegeneration Mechanisms
- Aldose Reductase and Taurine
- Retinoids in leukemia and cellular processes
- Natural Antidiabetic Agents Studies
- Antioxidant Activity and Oxidative Stress
- Curcumin's Biomedical Applications
Tehran University of Medical Sciences
2016-2025
Pharmaceutical Sciences Research Center
2011-2022
Islamic Azad University Pharmaceutical Sciences Branch
2022
Institute for Health Metrics and Evaluation
2022
University of Washington
2022
Academic Center for Education, Culture and Research
2018
University of Tehran
2011-2017
Razi Hospital
2011
Ibb University
2011
Islamic Azad University, Tehran
2010
AIM:To study the combinative effects of nanocerium and selenium in a murine model diabetes. METHODS:Cerium oxide (CeO2) nanoparticles (60 mg/kg per day) sodium selenite (5 μmol/kg alone or combination, metal form CeO2 mg/kg) were administered for 2 wk by intraperitoneal injection to streptozotocin-induced diabetic rats.At end treatment blood was collected, liver tissue dissected then oxidative stress markers, extent energy depletion lipid profile evaluated. RESULTS:Antioxidant enzymes high...
In this study, nanocomposite active films were fabricated containing silver nanoparticles (SNPs) embedded within soy protein isolate (SPI)/Persian gum (PG) matrices. The physical, mechanical, and antibacterial properties of these composite then characterized. addition, scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) used to provide information about the microstructure, interactions, crystallinity films. Pure SPI had poor...
In this research, a simple, label-free, and ultra-sensitive fluorescent platform based on metal-organic framework (MOF) has been developed to detect melamine in milk powder. This fluorescence sensor was fabricated from sensitized terbium (Tb)@NH2-MIL-253 (Al) MOF using hydrothermal method that involved combining the green emission of Tb (λem = 545 nm) with blue NH2-MIL-253(Al) 430 under single excitation wavelength (λex 335 nm). The then used optimized conditions (pH 9.0; concentration 30...
Type I diabetes mellitus is a metabolic disease caused by the impairment of pancreatic β-cells mainly mediated through oxidative stress and related apoptosis. Islets transplantation seems promising treatment for these patients, but during islets transplant, various types stresses to isolation procedure compromise function viability islets. We recently hypothesized that combination cerium oxide (CeO 2 ) yttrium (Y O 3 nanoparticles with potential free radical scavenger behavior should be...
In the present survey, plasma level of diazinon after acute exposure was measured by HPLC method at a time-course manner. addition, impact on expression key genes responsible for hepatocellular antioxidative defense, including PON1, GPx and CAT were investigated. The increase in oxidative damages treated rats determined measuring LPO, protein carbonyl content total antioxidant power plasma. After administration 85 mg/kg ten groups male Wistar different time points between 0-24 hours,...
There are increasing concerns regarding the toxic effects of chlorpyrifos (CPF) on human health. Curcumin (CUR) is a yellow pigment isolated from turmeric ground rhizome Curcuma longa Linn., which has been identified as an antioxidant agent. This study was designed to examine protective effect CUR and vitamin E (Vit E) CPF-induced lung toxicity. Rats were divided into seven groups: control, CPF (13.5 mg/kg, orally), + (100 300 respectively, α-tocopherol E, 150 intraperitoneally),...
Insulin Dependent Diabetes Mellitus (IDDM) is a disease with high incidence no pure cure therapy yet. In most of cases, these patients need pancreatic islets transplantation that not completely successful because oxidative stress happening during isolation and procedures. the present study, effective factors in procedure such as viability, insulin secretion, production reactive oxygen molecules (ROM), mitochondrial energy ATP/ADP ratio were examined isolated exposed to sodium selenite...