- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Urinary and Genital Oncology Studies
- Renal and related cancers
- Prostate Cancer Diagnosis and Treatment
- Urological Disorders and Treatments
- Prostate Cancer Treatment and Research
- Health Systems, Economic Evaluations, Quality of Life
- Urinary Bladder and Prostate Research
- Multiple and Secondary Primary Cancers
- Economic and Financial Impacts of Cancer
- Cancer Genomics and Diagnostics
- Cancer Diagnosis and Treatment
- Genital Health and Disease
- Tuberous Sclerosis Complex Research
- Sexual function and dysfunction studies
- Hormonal and reproductive studies
- Urinary Tract Infections Management
- Hernia repair and management
- Pelvic floor disorders treatments
- Ethics in Clinical Research
- Opioid Use Disorder Treatment
- Acute Kidney Injury Research
- Global Cancer Incidence and Screening
- Infectious Aortic and Vascular Conditions
Main Line Health
2020-2023
Lankenau Institute for Medical Research
2023
Fox Chase Cancer Center
2016-2019
Philadelphia University
2016-2018
Einstein Healthcare Network
2014-2017
Hahnemann University Hospital
2016
Philadelphia College of Osteopathic Medicine
2014
Einstein Medical Center Philadelphia
2014
The current study was performed to examine temporal trends and compare overall survival (OS) in patients undergoing radical cystectomy (RC) or bladder-preservation therapy (BPT) for muscle-invasive urothelial carcinoma of the bladder.The authors reviewed National Cancer Data Base identify with AJCC stage II III bladder from 2004 through 2013. Patients receiving BPT were stratified as having received any external-beam radiotherapy (any XRT), definitive XRT (50-80 grays), chemotherapy (CRT)....
Pathology consistent with that observed in Alzheimer's disease (AD) has previously been documented following intranasal infection of normal wild-type mice Chlamydia pneumoniae (Cpn) isolated from an AD brain (96-41). In the current study, BALB/c were intranasally infected a laboratory strain Cpn, AR-39, and olfactory bulbs obtained at 1-4 months post-infection (pi). Immunohistochemistry for amyloid beta or Cpn antigens was performed on sections brains mock-infected mice. Chlamydia-specific...
The Optilume BPH Catheter System is a novel drug/device combination minimally invasive surgical therapy for the treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia. PINNACLE study prospective, randomized, double-blind, sham-controlled clinical trial evaluating safety and efficacy against sham procedure.
Partial nephrectomy (PN) is recommended for localized T1a (≤4 cm) renal masses and preferred over radical (RN) amenable T1b/T2 (>4 tumors. The objective of the current study was to assess overall survival (OS) differences between PN RN in patients with T1 T2 cell carcinoma (RCC).The National Cancer Data Base queried RCC who underwent or from 2004 2014. Trends surgery were evaluated using Cochran-Armitage tests. Differences OS assessed adjusted Kaplan-Meier methods. effects procedure on...
Identification of pathogenic germline variants in patients with prostate cancer can help inform treatment selection, screening for secondary malignancies, and cascade testing. Limited real-world data are available on clinician recommendations following genetic testing cancer.
To evaluate a multicentre series of robot-assisted partial nephrectomy (RAPN) performed for the treatment large angiomyolipomas (AMLs).Between 2005 and 2016, 40 patients with or symptomatic AMLs underwent RAPN at five academic centres in USA. Patient demographics, AML characteristics, operative postoperative clinical outcomes were recorded analysed. Surgical compared between who selective arterial embolisation (SAE) before did not undergo pre-RAPN SAE.The median (interquartile range [IQR])...
To perform a retrospective analysis evaluating factors that may predict which men with elevated post-void residuals (PVRs) were at increased risk to develop acute urinary retention (AUR).We retrospectively analyzed the records of 44 male patients who had 2 consecutive PVRs greater than 100 ml over 6-month period. Using regression analysis, we evaluated patient's age, PVR volume, prostate specific antigen (PSA) and transrectal ultrasound volume respect development AUR 24 months.Of patients, 4...
Acute urinary retention • Obstructive uropathy Prolapse Renal injury insufficiencyPelvic organ prolapse can affect tract function by reducing flow rates and increasing post void residual urine volumes secondary to outlet obstruction.If the diagnosis is missed or left untreated, pelvic lead acute renal injury, chronic failure even end stage disease.Herein, we present a case of patient who presented Albert Einstein Medical Center in Philadelphia, PA with kidney complete uterine prolapse, also...
Priapism is defined as an erection lasting for more than 4 hours and can be grouped into 3 distinct subtypes: ischemic (low-flow), stuttering non-ischemic (high-flow). Herein, we present interesting case of conversion from a low-flow to high-flow priapism after distal shunting procedure. This rare phenomenon that has paucity documented cases. Diagnosis requires prompt clinical suspicion confirmatory testing including penile cavernosal blood gases Doppler ultrasound.
564 Background: While active surveillance has gained traction as a primary treatment strategy for small renal masses in patients with significant competing risks, population level trends of non-surgical management (NSM) remain poorly characterized. Using large national cancer registry, our objective was to assess temporal utilization NSM stage I cell carcinoma (RCC). Methods: The National Cancer Database (NCDB) queried all RCC from 2003-2012. Patients were categorized surgical intervention...
387 Background: To compare overall survival (OS) in patients undergoing radical cystectomy (RC) and bladder preservation therapy (BPT) for muscle invasive urothelial carcinoma of the bladder. Methods: We conducted a retrospective, observational cohort study which we reviewed National Cancer Database (NCDB) to identify with analytic stage II-III (N0M0) from 2003-2011. BPT were stratified as any external beam radiotherapy (EBRT), definitive (RT) [50-80Gy], RT + chemotherapy. Treatment trends...
Non-Hodgkin's lymphoma (NHL) represents 4% of newly diagnosed cancer in 2013 with a 59-82% 5-year survival depending on the tumor location. Primary presentation consists lymphadenopathy or swelling lymph nodes and non-specific systemic symptoms such as fevers, night sweats, weight loss. Less commonly, NHL arises from non-lymphoid tissue. We report unique case arising ureteral wall which was visualized via non-contrast CT direct vision through ureteroscopy.
You have accessJournal of UrologyBladder Cancer: Invasive V1 Apr 2017MP58-12 CLINICAL DESTINY OF INDETERMINATE PULMONARY NODULES IN PATIENTS UNDERGOING RADICAL CYSTECTOMY FOR UROTHELIAL CARCINOMA THE BLADDER David Cahn, Brian McGreen, Albert Lee, Karen Ruth, Elizabeth Plimack, Daniel Geynisman, Matthew Zibelman, Benjamin Ristau, Marc Smaldone, Richard Greenberg, Rosalia Viterbo, Chen, Robert Uzzo, and Alexander Kutikov CahnDavid Cahn More articles by this author , McGreenBrian McGreen...
You have accessJournal of UrologyProstate Cancer: Markers II (PD42)1 May 2024PD42-12 CLINICAL IMPACT OF AN INTEGRATED ExoDx PROSTATE BIOMARKER AND mpMRI FOR HGPCA RISK ASSESSMENT: PRACTICE PATTERNS, PERFORMANCE IN THE CLINIC Sonia Kumar, Christian Ray, Jason Alter, Yiyuan Yao, Vinita Verma, Johan Skog, Brian Haynes, Emily Ayre, Ronald F. Tutrone, and David Cahn KumarSonia Kumar , RayChristian Ray AlterJason Alter YaoYiyuan Yao VermaVinita Verma SkogJohan Skog HaynesBrian Haynes AyreEmily...