A5072432214- Chronic Obstructive Pulmonary Disease (COPD) Research
- COVID-19 Clinical Research Studies
- Heart Rate Variability and Autonomic Control
- Pediatric health and respiratory diseases
- Cardiovascular Syncope and Autonomic Disorders
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Respiratory viral infections research
- Neonatal Respiratory Health Research
- SARS-CoV-2 and COVID-19 Research
- Intensive Care Unit Cognitive Disorders
- Non-Invasive Vital Sign Monitoring
- Oral microbiology and periodontitis research
- Oral Health Pathology and Treatment
- Tracheal and airway disorders
- Peripheral Nerve Disorders
- Functional Brain Connectivity Studies
- Pleural and Pulmonary Diseases
- Orthopedic Surgery and Rehabilitation
- Obstructive Sleep Apnea Research
- Neurological disorders and treatments
- Pain Mechanisms and Treatments
- Sepsis Diagnosis and Treatment
- Genetic Neurodegenerative Diseases
- Intraoperative Neuromonitoring and Anesthetic Effects
Queen's University Belfast
2019-2025
Belfast Health and Social Care Trust
2020-2024
Mater Hospital
2023-2024
Queen's Hospital
2024
Canadian Respiratory Research Network
2023
Ulster Hospital
2014
University of Dundee
2013
Alfried Krupp Hospital
1995-2011
Essen University Hospital
2007
Massachusetts Institute of Technology
1999
Introduction Liberal administration of supplemental oxygen (O 2 ) is ubiquitous across numerous healthcare settings. However, appropriate O titration targets remain controversial and despite large-scale randomised trials, there an ongoing lack consensus regarding optimal oxygenation strategies the absence high-quality mechanistic data pertaining to potential proinflammatory effects hyperoxia. Methods analysis We hypothesise that (1) short-term exposure hyperoxia will induce mild pulmonary...
Lesions of the central sympathetic pathways are likely to be clinical relevance. In patients with acute stroke, in particular, they may responsible for partially deleterious cardiac arrhythmia. There is little knowledge organization above brainstem level both cardio-efferent and sudomotor fibers. We studied skin response (SSR) 29 stroke or infarction territory middle cerebral artery (MCA) order evaluate mediating emotional sweating. 24 (82.8%) SSR was pathological. These abnormalities were...
Transcranial magnetic stimulation (TMS) is a non-invasive diagnostic method particularly suited to investigation of the long motor tracts. The clinical value this in many cortical and subcortical diseases has been well established, but comparable studies for most spinal cord have still be made. Forty patients whom disease was established by examination, cerebrospinal fluid resonance imaging (MRI) were studied means somatosensory evoked potentials (SEP, median tibial nerve stimulation) (MEP,...
Epstein-Barr virus (EBV) frequently is measured at high levels in COPD using sputum quantitative polymerase chain reaction, whereas airway immunohistochemistry analysis has shown EBV detection to be common severe disease.
Abstract Aim To investigate whether there is an association between subgingival microbial diversity and reduced respiratory function. Materials Methods A group of dentate 58–72‐year‐old men in Northern Ireland had a comprehensive periodontal examination including plaque sampling. DNA was extracted from samples the V1–V3 regions 16S rRNA gene were analysed by high‐throughput sequencing index (MDI) derived. Spirometry measurements made using wedge bellows spirometer. The primary outcome...
Objective: Interstitial lung disease (ILD) is relatively common in patients with cancer an incidence of 7.5%. Historically pre-existing ILD was a contraindication to radical radiotherapy owing increased radiation pneumonitis rates, worsened fibrosis and poorer survival compared non-ILD cohorts. Herein, the clinical radiological toxicity outcomes contemporaneous cohort are described. Methods: Patients treated for at regional centre were collected prospectively. Radiotherapy planning, tumour...
Respiratory viral infections are closely associated with COPD exacerbations, hospitalisations, and significant morbidity mortality. The consequences of the persisting inflammation differentiation status in virus severe disease is not fully understood. aim this study was to evaluate barrier function, cellular architecture, inflammatory response bronchial epithelium human rhinovirus (HRV) induced pathological changes innate immune responses.Well-differentiated primary epithelial cells...