- Schizophrenia research and treatment
- Functional Brain Connectivity Studies
- Treatment of Major Depression
- Bipolar Disorder and Treatment
- Electroconvulsive Therapy Studies
- Autism Spectrum Disorder Research
- Attention Deficit Hyperactivity Disorder
- Advanced Neuroimaging Techniques and Applications
- Tryptophan and brain disorders
- Obsessive-Compulsive Spectrum Disorders
- Dementia and Cognitive Impairment Research
- Mental Health and Psychiatry
- Mental Health Research Topics
- Diet and metabolism studies
- Digital Mental Health Interventions
- Health Systems, Economic Evaluations, Quality of Life
- Heart Rate Variability and Autonomic Control
- Neurogenesis and neuroplasticity mechanisms
- Child and Adolescent Psychosocial and Emotional Development
- Neuroinflammation and Neurodegeneration Mechanisms
- Transcranial Magnetic Stimulation Studies
- Kidney Stones and Urolithiasis Treatments
- COVID-19 and Mental Health
- Gut microbiota and health
- Neuroscience and Neuropharmacology Research
Nara Medical University
2016-2025
Keio University
2016-2025
Okayama Saiseikai General Hospital
2025
Zucker Hillside Hospital
2013-2024
Northwell Health
2013-2024
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell
2018-2024
RIKEN Center for Advanced Intelligence Project
2019-2024
Feinstein Institute for Medical Research
2013-2023
Keio University Hospital
2005-2023
New York University
2023
Although non-adherence is common across all branches of medicine, psychotic disorders pose additional challenges that increase its risk. Despite the importance non-adherence, clinicians generally spend too little time on assessing and addressing adherence attitudes behaviors. Importantly, how measured significantly impacts findings, most frequently employed methods asking patients or judging indirectly based efficacy tolerability information have poor validity. Novel technologies are being...
<b><i>Background/Aims:</i></b> Dysbiosis is associated with various systemic disorders including irritable bowel syndrome (IBS). Fecal microbiota transplantation (FMT) might restore intestinal microbial balance. The study aimed to determine the safety and efficacy of FMT in IBS patients, as well also positive predictors for FMT. <b><i>Methods:</i></b> This was a single-arm, open-label study. Eligible patients were diagnosed based on Rome III...
Tumor-associated macrophages (TAMs) and cancer-associated fibroblasts (CAFs) are reported to be associated with poor prognosis, depending on their pro-tumoral roles. Current knowledge of TAMs CAFs in the tumor microenvironment urothelial cancer bladder (UCB) is limited. Therefore, we investigated paracrine effect induced by human UCB. For this, first carried out immunohistochemical analysis for CXCL1, CD204 (TAM marker), αSMA (CAF E-cadherin, MMP2 using 155 UBC tissue samples. Next,...
Introduction: Electroconvulsive therapy (ECT) has antidepressant effects, but it also possible cognitive side effects. The effects of ECT on neuronal oscillatory pattern and phase synchronization, the relationship between clinical response or change electroencephalogram (EEG) measurements remain elusive. Methods: Individuals with unipolar depressive disorder receiving bilateral were recruited. Five minutes resting, eyes-closed, 19-lead EEG recordings obtained before after a course ECT....
Abstract Microglia and brain-derived neurotrophic factor (BDNF) are essential for the neuroplasticity that characterizes critical developmental periods. The experience-dependent development of social behaviors—associated with medial prefrontal cortex (mPFC)—has a period during juvenile in mice. However, whether microglia BDNF affect remains unclear. Herein, we aimed to elucidate effects microglia-derived on behaviors mPFC development. Mice underwent isolation p21–p35 had increased Bdnf...
To understand the mechanisms by which large increases in serum amyloid A (SAA) occur during acute phase response, human hepatoma cells were transfected with SAA2 gene reporter plasmids and stimulated combinations of cytokines. Although interleukin-1 (IL-1) interleukin-6 (IL-6) transcription from this promoter individually, addition both mediators produced a response between two nine times greater than expected additive response. This synergistic activation was dependent on integrity at least...
Research on the adverse effects of Internet use has gained importance recently. However, there is currently insufficient data Japanese young adults' use, so we conducted a survey targeting university students to research problematic (PIU). We also investigated relationship between PIU and multiple psychiatric symptoms.A paper-based was at five universities in Japan. Respondents were asked fill out self-report scales regarding their dependency using Addiction Test (IAT). Sleep quality,...