A5104187899- HIV Research and Treatment
- Nuclear Structure and Function
- HIV/AIDS drug development and treatment
- RNA Research and Splicing
- COVID-19 epidemiological studies
- Cytomegalovirus and herpesvirus research
- COVID-19 Clinical Research Studies
- COVID-19 and Mental Health
The University of Texas at El Paso
2024
Vanderbilt University Medical Center
2023-2024
HIV-1 infection requires passage of the viral core through nuclear pore cell, a process that depends on functions capsid. Recent studies have shown cores enter nucleus prior to capsid disassembly. Interactions with complex are necessary but not sufficient for entry, and mechanism by which traverses comparably sized is unknown. Here we show highly elastic this property linked entry infectivity. Using atomic force microscopy-based approaches, found purified wild type rapidly returned their...
HIV-1 infection requires passage of the viral core through nuclear pore cell, a process that depends on functions capsid 1,2 . Recent studies have shown HIV- 1 cores enter nucleus prior to disassembly 3–5 Interactions with complex are necessary but not sufficient for entry, and mechanism by which traverses comparably sized is unknown. Here we show highly elastic this property linked entry infectivity. Using atomic force microscopy-based approaches, found purified wild type rapidly returned...
In response to the SARS-CoV-2 pandemic, United States declared a state of emergency and implemented large-scale shutdowns public health initiatives prevent overwhelming resources. The success these prevention methods remains unresolved as restrictions implementation varied from national, state, local levels. Despite national regulations, individual adherence preventative guidelines presented an additional layer variability. Cases COVID-19 continued rise fall over two-year period on level,...